Serum Glycated Albumin to Guide the Diagnosis of Diabetes Mellitus.
In the diagnosis of diabetes mellitus, hemoglobin A1c (HbA1c) is sometimes measured to determine the need of an oral glucose tolerance test (OGTT). However, HbA1c does not accurately reflect glycemic status in certain conditions. This study was performed
Wan-Chen Wu +9 more
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Effect of Papaverine on Human Serum Albumin Glycation
Background: Glycation is a non enzymatic reaction initiated by the primary addition of sugar to the amino groups of proteins.In the early stage of glyction, the synthesis of intermediates leading to formation of Amadori compounds occurs.
A Ahmadzadeh, M Feizie, R Ghafarzadegan
doaj +1 more source
A biophysical comparison of human serum albumin to be glycated in vivo and in vitro [PDF]
The glycation process includes the arrangement of proteins with chemically reversible early glycation products, Schiff bases and Amadori adducts. These early products endure slow and complex rearrangements to create advanced glycation end-products (AGEs)
Sattarahmady Naghmeh +2 more
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Tuning Human Serum Albumin (HSA) Hydrogels through Albumin Glycation
AbstractThe changes of technological properties of albumin‐based hydrogels induced by increasing degrees of post‐translational modification of the protein are reported. Maillard‐type modification of amino acids arginine and lysine of albumin is achieved through glyoxal as an α‐dicarbonyl compound.
Jonas Volmer +4 more
openaire +4 more sources
An immobilization-free electrochemical sensor coupled with a graphene oxide (GO)-based aptasensor was developed for glycated human serum albumin (GHSA) detection.
Wassa Waiwinya +5 more
doaj +1 more source
Binding of tolbutamide to glycated human serum albumin [PDF]
The presence of elevated levels of glucose in blood during diabetes can lead to the non-enzymatic glycation of serum proteins such as human serum albumin (HSA). This study examined the changes that occur in binding of the sulfonylurea drug tolbutamide to HSA as the level of glycation for this protein was increased.
Joseph, K.S. +2 more
openaire +2 more sources
Elevated hemoglobin glycation index identify non-diabetic individuals at increased risk of kidney dysfunction [PDF]
Hemoglobin glycation index (HGI), calculated as the difference between the observed value of HbA1 and the predicted HbA1c based on plasma glucose concentration, is a measure of the individual tendency toward non-enzymatic hemoglobin glycation which has ...
Andreozzi, F +6 more
core +3 more sources
Ischaemia-modified Albumin Estimation and Usefulness of Different Albumin Adjustment as a Marker to Predict Kidney Damage in Diabetes Mellitus [PDF]
Introduction: Urine Albumin Creatinine Ratio (UACR) has been the standard for detecting albuminuria in diabetes mellitus, but the presence of “non albuminuric renal impairment” has encouraged the search for novel markers.
Afzal Ahmad +3 more
doaj +1 more source
Serum glycated albumin as a new glycemic marker in pediatric diabetes [PDF]
PurposeSerum glycated albumin (GA) has been recently used as another glycemic marker that reflects shorter term glycemic control than glycated hemoglobin (HbA1c).
Ji Woo Lee +6 more
doaj +1 more source
Glycated Albumin as an Outcome Predictor in Pregnant Women with Diabetes Mellitus
Objective: To determine the correlation between Glycated Albumin concentrations with the outcome of pregnant women with Type 2 Diabetes Mellitus in Zainoel Abidin Hospital, Banda Aceh.
Cut M. Yeni +3 more
doaj +1 more source

