Results 61 to 70 of about 158,760 (393)

Selective disappearance of individuals with high levels of glycated haemoglobin in a free-living bird [PDF]

open access: yes, 2016
This work was supported by the ANR (ANR-06-JCJC0082 to B.D.), the CNRS (PEPS INEE and PICS France–Switzerland to B.D.), the French Ministe`re de l’Enseignement Supe´rieur et de la Recherche (PhD fellowship to C.R.), the Re´gion Rhoˆne-Alpes (Explora’doc ...
Bize, Pierre   +4 more
core   +2 more sources

Advanced Glycation End Products and Diabetic Complications

open access: yesKorean Journal of Physiology and Pharmacology, 2014
During long standing hyperglycaemic state in diabetes mellitus, glucose forms covalent adducts with the plasma proteins through a non-enzymatic process known as glycation.
Varun Singh   +3 more
semanticscholar   +1 more source

In Vitro Investigations of Acetohexamide Binding to Glycated Serum Albumin in the Presence of Fatty Acid

open access: yesMolecules, 2020
The interaction of drugs with human serum albumin (HSA) is an important element of therapy. Albumin affects the distribution of the drug substance in the body, as well as its pharmacokinetic and pharmacodynamic properties.
Agnieszka Szkudlarek   +2 more
doaj   +1 more source

Effect of transferrin glycation induced by high glucose on HK-2 cells in vitro

open access: yesFrontiers in Endocrinology, 2023
Background and objectiveGlycation is a common post-transcriptional modification of proteins. Previous studies have shown that advanced glycation end modified transferrin (AGE-Tf) levels in diabetic rat kidney tissues were increased; however, its role in ...
Yanqi Ma   +7 more
doaj   +1 more source

Evaluation of Glycated Albumin (GA) and GA/Hba1c Ratio for Diagnosis of Diabetes and Glycemic Control: A Comprehensive Review [PDF]

open access: yes, 2017
Diabetes Mellitus (DM) is a group of metabolic diseases characterized by chronic high blood glucose concentrations (hyperglycemia). When it is left untreated or improperly managed, it can lead to acute complications including diabetic ketoacidosis and ...
Abdolrahim, Mojgan   +6 more
core   +3 more sources

The AGE-RAGE Axis: Implications for Age-Associated Arterial Diseases

open access: yesFrontiers in Genetics, 2017
The process of advanced glycation leads to the generation and accumulation of an heterogeneous class of molecules called advanced glycation endproducts, or AGEs.
Laura M. Senatus, Ann Marie Schmidt
doaj   +1 more source

Definition of the upper reference limit of glycated albumin in blood donors from Italy [PDF]

open access: yes, 2017
Glycated Albumin (GA) has been proposed as a short-term indicator of glycemic homeostasis. The aim of this study is to describe the distribution of GA in a large sample of blood donors from Italy to evaluate whether demographic features, namely age and ...
Agnello, Luisa   +7 more
core   +1 more source

Failure of Common Glycation Assays to Detect Glycation by Fructose

open access: yesClinical Chemistry, 1992
Abstract Serum albumin was modified by in vitro glycation with either fructose or glucose, to see whether the common clinical assays for glycation were able to detect both fructose- and glucose-induced changes in protein structure in diabetes.
Nessar Ahmed, Anna J. Furth
openaire   +3 more sources

Advanced Glycation End Products and Oxidative Stress in Type 2 Diabetes Mellitus

open access: yesBiomolecules, 2015
Type 2 diabetes mellitus (T2DM) is a very complex and multifactorial metabolic disease characterized by insulin resistance and β cell failure leading to elevated blood glucose levels.
K. Nowotny   +4 more
semanticscholar   +1 more source

Role of galectin-3 in bone cell differentiation, bone pathophysiology and vascular osteogenesis [PDF]

open access: yes, 2017
Galectin-3 is expressed in various tissues, including the bone, where it is considered a marker of chondrogenic and osteogenic cell lineages. Galectin-3 protein was found to be increased in the differentiated chondrocytes of the metaphyseal plate ...
Fantauzzi, Claudia Blasetti   +3 more
core   +5 more sources

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