Results 141 to 150 of about 44,199 (236)

Blockade of cannabinoid CB1 receptors potentiates the anti‐fibrotic effects mediated by SGLT2 inhibition in a mouse model of diabetic nephropathy

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 21, Page 5355-5377, November 2025.
Background and purpose Diabetic nephropathy (DN) is a common complication of diabetes. Current treatments include renin‐angiotensin‐aldosterone system (RAAS) blockers and sodium‐glucose co‐transporter 2 (SGLT2) inhibitors. The cannabinoid CB1 receptor is a potential therapeutic target.
Océane Pointeau   +20 more
wiley   +1 more source

Exploring the Interplay Between Glycated Albumin, AGEs, and Inflammation in Old Patients with CKD. [PDF]

open access: yesMetabolites
Vettoretti S   +7 more
europepmc   +1 more source

The Role of Micronutrients in Atherosclerosis: Mechanisms and Clinical Application

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.
ABSTRACT Micronutrients, though required in relatively small quantities by the human body, are essential for maintaining normal physiological functions and play a crucial role in the prevention and management of various diseases. Atherosclerosis (AS) is a common chronic inflammatory condition that often presents without obvious symptoms in its early ...
Yuxin Ouyang   +5 more
wiley   +1 more source

Exploring the Causal Relationship Between Blood Metabolites and Chronic Periodontitis: Insights From Genetic Causal Analysis

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.
ABSTRACT To investigate the potential bidirectional causal relationship between specific blood metabolites and chronic periodontitis using Mendelian randomisation (MR). A two‐sample bidirectional MR analysis was conducted. Data on 1400 blood metabolites were obtained from a genome‐wide association study involving 8299 participants.
Weilun Cai   +8 more
wiley   +1 more source

Histidine‐Containing Dipeptides in Obesity and Cardiometabolic Health: A Systematic Scoping Review

open access: yesObesity Reviews, Volume 26, Issue 11, November 2025.
ABSTRACT Background Histidine‐containing dipeptides (HCDs) have been reported to have anti‐inflammatory and antidiabetic properties. Yet, no previous reviews have examined the impact of HCDs on Type 2 diabetes (T2D) risk factors (e.g., obesity) and progression (e.g., microvascular and macrovascular complications).
Saeede Saadati   +10 more
wiley   +1 more source

Relationship Between Advanced Glycation End-Products and Cardiovascular Disease [PDF]

open access: yesAvicenna Journal of Medical Biochemistry, 2018
Jamshid Karimi
doaj   +1 more source

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