Results 41 to 50 of about 44,199 (236)
Cells, 2021 Systemic lupus erythematosus (SLE) is characterized by abnormal action of the immune system and a state of chronic inflammation. The disease can cause life-threatening complications.
Agnieszka Nowak +5 more
doaj +1 more source
Advanced Science, EarlyView.1) 14, 15‐EET levels were decreased in ovarian granulosa cells, follicular fluid, peritoneal fluid from endometriosis patients. 2) EETs reduction in endometriosis follicular fluid aggravated granulosa cell senescence. 3) ROS reduced 14, 15‐EET levels by upregulating EPHX2 through a mechanism involving histone methylation modification.
Xiang Lin +11 more
wiley +1 more source
Advanced Glycation End Products As Biomarkers in Systemic Diseases: Premises and Perspectives of Salivary Advanced Glycation End Products [PDF]
Biomarkers in Medicine, 2019 Advanced glycation end products (AGEs) are glycated proteins associated with high dry temperature food processing, coloring and flavor modification of food products. Previous studies on diet-related disease support the role of the glycation products as biomarkers in local and general proinflammatory response.
Babtan A. M. +8 more
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Advanced Science, EarlyView.tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan +10 more
wiley +1 more source
Research Progress on Natural Products Inhibiting Advanced Glycation End Products [PDF]
Shipin KexueGlycation is the non-enzymatic reaction between sugars (glucose and fructose) and proteins or lipids, giving rise to the formation of advanced glycation end products (AGEs).
QI Yawei, LIU Haochi, LIU Jifeng
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Inhibition of advanced glycated end-products
Postgraduate Medical Journal, 1999 Sir, Szalecksy and colleagues raise an interesting series of points on the enzymatic antioxidant defence system and its role in the pathogenesis of diabetic complications when its function of free-radical clearance is impaired.1 It is conceivable that one of the ways in which the scavenging function of the antioxidant enzymes may be reduced is by ...
A. Somogyi +4 more
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Advanced Science, EarlyView.This study establishes a bio‐electroceutical interface by synergizing engineered exosome‐derived biological signals with electroconductive microneedle‐delivered electrical cues, achieving dual‐pathway reprogramming of the diabetic neurovascular niches and accelerating wound healing. Abstract Diabetic wound healing remains a major clinical challenge due
Di Liu +5 more
wiley +1 more source
Advanced glycation end products and human diseases
Journal of Biological ResearchProteins, lipids, and nucleic acids can undergo non-enzymatic glycation and oxidation, leading to the formation of Advanced Glycation End products (AGEs).
Hamad Abu Zahra
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Journal of the Formosan Medical Association, 2015 Blockade of advanced glycation end-products (AGE) is able to reduce diabetic complications and control periodontitis. This study aimed to determine whether the application of aminoguanidine (AG), an AGE inhibitor, or N-phenacylthiazolium bromide (PTB ...
Sheng-Chueh Tsai +6 more
doaj +1 more source
Zinc against advanced glycation end products [PDF]
Clinical and Experimental Pharmacology and Physiology, 2018 SummaryAdvanced glycation end products (AGEs) are destructive compounds with pathogenic importance in age‐related chronic diseases. Zinc has antioxidant, anti‐inflammatory and anti‐apoptotic potential. This study aimed to summarize effects of zinc onAGEformation andAGE‐induced damaging agents.
Sorayya Kheirouri +2 more
openaire +3 more sources