Results 51 to 60 of about 87,030 (164)

Oxidative stress, protein glycation and nutrition – interactions relevant to health and disease throughout the lifecycle [PDF]

open access: yes, 2014
Protein glycation has been studied for over a century now and plays an important role in disease pathogenesis throughout the lifecycle. Strongly related to diabetic complications, glycation of Hb has become the gold standard method for diabetes diagnosis
American Diabetes   +17 more
core   +3 more sources

Receptor for advanced glycation end products and its involvement in inflammatory diseases [PDF]

open access: yes, 2013
The receptor for advanced glycation end products (RAGE) is a transmembrane receptor of the immunoglobulin superfamily, capable of binding a broad repertoire of ligands. RAGE-ligands interaction induces a series of signal transduction cascades and lead to
Basir, Rusliza   +4 more
core   +3 more sources

Advanced glycation end-products: Mechanics of aged collagen from molecule to tissue [PDF]

open access: yes, 2017
Concurrent with a progressive loss of regenerative capacity, connective tissue aging is characterized by a progressive accumulation of Advanced Glycation End-products (AGEs).
Andreassen   +59 more
core   +1 more source

Advanced glycation end products and human diseases

open access: yesJournal of Biological Research
Proteins, lipids, and nucleic acids can undergo non-enzymatic glycation and oxidation, leading to the formation of Advanced Glycation End products (AGEs).
Hamad Abu Zahra
doaj   +1 more source

Research Progress on Natural Products Inhibiting Advanced Glycation End Products [PDF]

open access: yesShipin Kexue
Glycation is the non-enzymatic reaction between sugars (glucose and fructose) and proteins or lipids, giving rise to the formation of advanced glycation end products (AGEs).
QI Yawei, LIU Haochi, LIU Jifeng
doaj   +1 more source

Opposing effects of bisphosphonates and advanced glycation end-products on osteoblastic cells [PDF]

open access: yes, 2008
Patients with long-standing Diabetes mellitus can develop osteopenia and osteoporosis. We have previously shown that advanced glycation endproducts reduce the bone-forming activity of osteoblasts.
Arnol, Verónica   +4 more
core   +2 more sources

Osseous wound repair under inhibition of the axis of advanced glycation end-products and the advanced glycation end-products receptor

open access: yesJournal of the Formosan Medical Association, 2015
Blockade of advanced glycation end-products (AGE) is able to reduce diabetic complications and control periodontitis. This study aimed to determine whether the application of aminoguanidine (AG), an AGE inhibitor, or N-phenacylthiazolium bromide (PTB ...
Sheng-Chueh Tsai   +6 more
doaj   +1 more source

Advanced Glycation End-Products (AGEs) and Their Soluble Receptor (sRAGE) in Women Suffering from Systemic Lupus Erythematosus (SLE)

open access: yesCells, 2021
Systemic lupus erythematosus (SLE) is characterized by abnormal action of the immune system and a state of chronic inflammation. The disease can cause life-threatening complications.
Agnieszka Nowak   +5 more
doaj   +1 more source

RAGE Signaling in Skeletal Biology [PDF]

open access: yes, 2019
PURPOSE OF REVIEW: The receptor for advanced glycation end products (RAGE) and several of its ligands have been implicated in the onset and progression of pathologies associated with aging, chronic inflammation, and cellular stress. In particular, the
Davis, Hannah M.   +2 more
core   +2 more sources

Research Progress on Advanced Glycation End Products in Aging-related Diseases

open access: yesGuoji laonian yixue zazhi
Aging is an inherent physiological phenomenon that occurs throughout human life. Numerous theories have been proposed to elucidate the distinctive features of aging, encompassing oxidative stress, imbalances in protein homeostasis, deterioration of gene ...
Yanling Shen   +3 more
doaj   +1 more source

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