Results 71 to 80 of about 8,152,704 (249)

Research Progress on Advanced Glycation End Products in Aging-related Diseases

open access: yesGuoji laonian yixue zazhi
Aging is an inherent physiological phenomenon that occurs throughout human life. Numerous theories have been proposed to elucidate the distinctive features of aging, encompassing oxidative stress, imbalances in protein homeostasis, deterioration of gene ...
Yanling Shen   +3 more
doaj   +1 more source

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

open access: yesAdvanced Science, EarlyView.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao   +10 more
wiley   +1 more source

Prevention of Arterial Stiffening by Pyridoxamine in Diabetes Is Associated with Inhibition of the Pathogenic Glycation on Aortic Collagen

open access: yes, 2010
Background and purpose: Our team previously demonstrated that diabetes induces a deterioration in vascular dynamics, in parallel with the enhanced formation of advanced glycation end products.
張國柱;梁金銅;蔡佩珊;吳明修;許寬立   +1 more
core   +1 more source

Advanced glycation end-products in liver diseases: Meta analysis

open access: yes, 2021
A meta-analysis examining serum levels of advanced glycation end-products in non-alcoholic fatty-liver disease (NAFLD) and alcoholic liver disease (ALD).
Kamil Litwinowicz
core   +1 more source

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

Vascular Effects of Dietary Advanced Glycation End Products

open access: yesInternational Journal of Endocrinology, 2015
Evidence has accumulated lately demonstrating that advanced glycation end products (AGEs) play an important role in the development of diabetic and cardiovascular complications as well as the development of other chronic diseases.
Alin Stirban, Diethelm Tschöpe
doaj   +1 more source

Advanced glycation end-products induce skeletal muscle atrophy and dysfunction in diabetic mice via a RAGE-mediated, AMPK-down-regulated, Akt pathway

open access: yes, 2017
Diabetic myopathy, a less studied complication of diabetes, exhibits the clinical observations characterized by a less muscle mass, muscle weakness and a reduced physical functional capacity.
蔡克嵩;楊庭華;詹鼎正;劉興華;姜至剛;楊榮森   +1 more
core   +1 more source

Toxicity of advanced glycation end products (Review)

open access: yesBiomedical Reports, 2021
Advanced glycation end-products (AGEs) are proteins or lipids glycated nonenzymatically by glucose, or other reducing sugars and their derivatives, such as glyceraldehyde, glycolaldehyde, methyloglyoxal and acetaldehyde. There are three different means of AGE formation: i) Maillard reactions, the polyol pathway and lipid peroxidation.
openaire   +4 more sources

Arthroscopic Images Predict Tendon Integrity After Arthroscopic Rotator Cuff Repair Using a Deep Learning Model

open access: yesArthroscopy, EarlyView.
Purpose To assess the feasibility of a deep learning model for predicting early structural integrity after arthroscopic rotator cuff repair (ARCR) using intraoperative arthroscopic images obtained after the double‐row bridging repair technique. Methods This retrospective study included patients who underwent ARCR between January 2016 and June 2024 ...
Kuan‐Ting Wu   +5 more
wiley   +1 more source

Advanced glycation end products, dementia, and diabetes [PDF]

open access: yesProceedings of the National Academy of Sciences, 2014
It is becoming abundantly clear that the insight into the pathological process of Alzheimer’s disease (AD) provided through autosomal dominant variants of the condition is only a partial one. The formation and aggregation of Aβ and the phosphorylation and aggregation of tau are clearly part of the core pathogenesis.
Simon, Lovestone, Ulf, Smith
openaire   +2 more sources

Home - About - Disclaimer - Privacy