Results 91 to 100 of about 87,030 (164)

The Anti-AGEing and RAGEing Potential of Isothiocyanates

Molecules
Isothiocyanates (ITCs), found in edible plants such as cruciferous vegetables, are a group of reactive organo-sulfur phytochemicals produced by the hydrolysis of precursors known as glucosinolates.
Bradley A. Krisanits, Bhoomika Kaur, Jed W. Fahey, David P. Turner   +3 more
doaj   +1 more source

Targeting the AGEs-RAGE axis: pathogenic mechanisms and therapeutic interventions in diabetic wound healing

Frontiers in Medicine
Diabetes is a global health problem, with diabetic wounds constituting one of its most severe complications. Advanced glycation end products (AGEs) and their receptor, the receptor for advanced glycation end products (RAGE), play a key role in the ...
Haohui Lin, Yi Yang, Xia Wang, Manhon Chung, Li Zhang, Sa Cai, Xiaohua Pan, Yu Pan   +7 more
doaj   +1 more source

Assessment of Oral Glycine and Lysine Therapy on Receptor for Advanced Glycation End Products and Transforming Growth Factor Beta Expression in the Kidney of Streptozotocin-Induced Diabetic Rats in Comparison with Normal Rats [PDF]

Journal of Kerman University of Medical Sciences, 2014
Background & Aims: Today, diabetic nephropathy is considered to be one of the most common causes of end stage renal disease. Uncontrolled hyperglycemia, and consequently, production of advanced glycation end products activate pathways which play key ...
Somayeh Sadat Heidary, Sayedeh Zahra Bathaie, Fereshteh Bahmani, Gholamreza Moshtaghi Kashanian   +3 more
doaj  

Sex-specific differences of advanced glycation end products in diabetes

Nutrition & Diabetes
Advanced glycation end products (AGEs) are formed through non-enzymatic glycation reactions and accumulate in tissues, particularly under pathological conditions such as diabetes mellitus.
Michael Hellwig, Julia Decker, Leticia Prates Roma, Stefan Schunk, Emmanuel Ampofo, Sandra Rother   +5 more
doaj   +1 more source

Serum markers of bone fragility in type-2 diabetes mellitus [PDF]

, 2019
Patients with type-2 diabetes mellitus (T2DM) have normal or increased bone mineral density (BMD) but despite that, they are characterized by an increased hip and vertebral fracture risk that involves the alteration of bone quality and not the reduction ...
Dănciulescu Miulescu, Rucsandra, Guja, Loreta, Ochiana, Lavinia Claudia, Ungurianu, Anca, Șeremet, Oana Cristina, Ștefănescu, Emil   +5 more
core   +1 more source

Transcriptional regulation of endothelin-1 expression by advanced glycation end-products in human aortic endothelium is mediated via NF-kappaΒ and AP-1 [PDF]

, 2012
Advanced Glycation End-products (AGEs) are produced by the non-enzymatic glycation of proteins, lipids and nucleic acids, resulting in an overload of highly reactive molecules of endogenous or exogenous (dietary) origin.
Adamopoulos, Christos, Dalagiorgou, Georgia, Diamanti-Kandarakis, Evanthia, Gargalionis, Antonios N., Kandaraki, Eleni A., Papavassiliou, Athanasios G., Piperi, Christina   +6 more
core  

Altered Cell-surface Receptor Levels Result from Fructose Advanced Glycation End Product-Induced Inflammation [PDF]

, 2014
Objective: As a result of the heightened reactivity fructose demonstrates compared to glucose and our current knowledge of glucose advanced glycation end-products, the aim of this research was to further elucidate the proinflammatory pathways involved in
Blackley, Regina, Lull, Melinda E., Stryker, Matthew   +2 more
core   +1 more source

Protein glycoxidation in neuropsychiatric disorders-from basic research to clinical practice. [PDF]

Redox Biol
Orlof W, Maciejczyk M.
europepmc   +1 more source

Prediction and Characterization of Glycated Peptides and Proteins using Hydrophilic Interaction Liquid Chromatography coupled with Mass Spectrometry (HILIC-MS). [PDF]

J Biomol Tech
Priya S, Kowalski EL, Popov M, Orlando R.   +3 more
europepmc   +1 more source

Regenerative Therapies for Cosmetic Dermatology for Patients with Diabetes Mellitus: Skin Aging, Aesthetic Concerns, and Evidence-Based Best Practices. [PDF]

Int J Mol Sci
Odeh TT, Patel DA, Pradeep PM, Patel JA, Mittal R, Hirani K.   +5 more
europepmc   +1 more source