Results 91 to 100 of about 8,152,704 (249)

Effects of atorvastatin on serum soluble receptors for advanced glycation end-products in type 2 diabetes

, 2010
Objective: The receptor for advanced glycation end-products (RAGE) plays an important role in the pathogenesis of diabetic complications and atherosclerosis.
Wong, Y, Betteridge, DJ, Tan, KCB, Tam, HL, Shiu, SWM, Chow, WS   +5 more
core   +1 more source

AKTIVITAS ANTIFOTOOKSIDASI DAN PENGHAMBAT PEMBENTUKAN AGES (ADVANCED GLYCATION END-PRODUCTS) DARI FRAKSI ALGA Padina australis [PDF]

, 2018
AKTIVITAS ANTIFOTOOKSIDASI DAN PENGHAMBAT PEMBENTUKAN AGES (ADVANCED GLYCATION END-PRODUCTS) DARI FRAKSI ALGA Padina australisSyutria Trifosa Kondoj1), Edi Suryanto2), Max Runtuwene2)1)Program Studi Farmasi FMIPA Unsrat Manado, 951152)Jurusan Kimia FMIPA
Kondoj, Syutria T.
core   +1 more source

Modulation of soluble receptor for advanced glycation end products isoforms and advanced glycation end products in long-living individuals

, 2021
Background: Circulating levels of soluble receptor for advanced glycation end products (sRAGE) and advanced glycation end products (AGEs) correlate with aging/cardiovascular risk, which is delayed in long-living individuals (LLIs).
Scavello F., Raucci A., Castiglione S., MacIag A., Spinetti G., Tedesco C. C., Veglia F., Puca A. A., Sangalli E.   +8 more
core   +1 more source

The Impact of Glycation on Protein Digestibility

ChemFoodChem, EarlyView.
Schematic overview of how protein glycation affects digestibility and downstream nutritional consequences. Glycation‐derived structural modifications reduce protease accessibility, leading to limited hydrolysis and altered peptide generation. These changes decrease amino acid bioavailability and may subsequently contribute to microbiome alterations ...
Lea Hönemann, Simone Lipinski, Jana Raupbach   +2 more
wiley   +1 more source

Association of accumulated advanced glycation end‐products with a high prevalence of sarcopenia and dynapenia in patients with type 2 diabetes

Journal of Diabetes Investigation, 2019
Aims/Introduction Advanced glycation end‐products (AGEs), which are a major cause of diabetic vascular complications, accumulate in various tissues under chronic hyperglycemic conditions, as well as with aging in patients with diabetes.
Hiroyasu Mori, Akio Kuroda, Masashi Ishizu, Mami Ohishi, Yuichi Takashi, Yinhua Otsuka, Satoshi Taniguchi, Motoyuki Tamaki, Kiyoe Kurahashi, Sumiko Yoshida, Itsuro Endo, Ken‐ichi Aihara, Makoto Funaki, Yuko Akehi, Munehide Matsuhisa   +14 more
doaj   +1 more source

Pathological Role of Receptor for Advanced Glycation End Products in Calcified Aortic Valve Stenosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Aortic stenosis (AS) is highly prevalent in patients with atherosclerotic cardiovascular disease. Advanced glycation end products (AGEs) and the receptor for AGEs (RAGE) play a pivotal role for vascular calcification in atherosclerosis.
Kosuke Saku, Nobuhiro Tahara, Tohru Takaseya, Hiroyuki Otsuka, Kazuyoshi Takagi, Takahiro Shojima, Yusuke Shintani, Yasuyuki Zaima, Satoshi Kikusaki, Tomofumi Fukuda, Atsunobu Oryoji, Yuri Nishino, Takanori Matsui, Tatsuyuki Kakuma, Jun Akiba, Yoshihiro Fukumoto, Sho‐ichi Yamagishi, Hiroyuki Tanaka   +17 more
doaj   +1 more source

Advanced glycation end-products in diabetic nephropathy [PDF]

Nephrology Dialysis Transplantation, 1999
Throughout the industrialized (well-fed) world, diabetes mellitus is the most prevalent cause of end-stage renal disease (ESRD). Diabetic nephropathy is as likely to develop in long-duration non-insulin-dependent diabetes (type 2) as in insulin-dependent diabetes mellitus (type 1).
openaire   +2 more sources

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Effects of advanced glycation end-products on the proliferation and differentiation of osteoblast-like cells [PDF]

, 1997
Two different lines of osteoblast-like cells were used to investigate the effect of advanced glycation end-products of bovine serum albumin on cell proliferation and differentiation. These parameters were found to be both dose- and time-dependent.
McCarthy, Antonio Desmond, Cortizo, Ana María, Bruzzone, Liliana, Etcheverry, Susana B.   +3 more
core   +1 more source