Results 111 to 120 of about 8,152,704 (249)
Interaction of receptor for advanced glycation end products with advanced oxidation protein products induces podocyte injury [PDF]
, 2012 Chronic kidney disease (CKD) is characterized by progressive decline in renal function. Podocyte dropouts contribute to the pathogenesis of diabetic and nondiabetic CKD.
Yamamoto, Yasuhiko, Yamamoto, Hiroshi
core +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.Type 2 diabetes mellitus (T2DM) is associated with chronic low‐grade systemic inflammation. This study evaluated the neutrophil‐to‐lymphocyte ratio (NLR) as a practical inflammatory biomarker in T2DM. A cross‐sectional study was conducted in Hodeidah City among 82 participants: 42 T2DM patients and 40 healthy controls.
Yousef A. D. Alkhadem +6 more
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 Background Chronic deposits of advanced glycation end products produced by enzymatic glycation have been suggested as predictors of atherosclerotic‐related disorders.
Ivan Cavero‐Redondo +7 more
doaj +1 more source
Advanced glycation end-products and bone fractures [PDF]
IBMS BoneKEy, 2009 Bone does not turn over uniformly, and becomes susceptible to post-translational modification by non-enzymatic glycation (NEG). NEG of bone causes the formation of advanced glycation end-products (AGEs) and this process is accelerated with aging, diabetes and antiresorptive postmenopausal osteoporosis therapy.
openaire +2 more sources
Effect of protein glycation by methylglyoxal on pancreatic beta cell function [PDF]
Methylglyoxal is a physiological dicarbonyl metabolite and potent argininedirected glycating agent. It often modifies proteins at functional sites producing loss of positive charge, structural distortion and inactivation.
Tym, Amy
core
A Chemoproteomic Approach to Study Advanced Glycation End-Products [PDF]
Protein glycation is a non-enzymatic process in which an arginine or lysine residue of a protein reacts irreversibly with a carbohydrate or a dicarbonyl compound.
Sokoliova, Saskia
core +1 more source
Inhibition of protein glycation and advanced glycation end products by ascorbic acid [PDF]
, 2016 Advanced glycation end products (AGEs) formation is increased in diabetes mellitus, leading to microvascular and macrovascular complications. Recently, much attention has been focused on natural and synthetic inhibitors to delay the onset or progression ...
Zafar, Hira +3 more
core +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.This graphical abstract illustrates the dynamic bidirectional crosstalk between microRNA biogenesis and autophagy, which serves as a critical regulatory axis in cardiovascular homeostasis. We highlight how specific miRNAs modulate autophagic flux to mitigate vascular inflammation and plaque instability, while concurrently, the autophagic machinery ...
Sepehr Ebrahimi‐Dehkordi +11 more
wiley +1 more source
AKTIVITAS ANTIFOTOOKSIDASI DAN PENGHAMBATAN PEMBENTUKKAN AGEs (ADVANCED GLYCATION END PRODUCTS) EKSTRAK KULIT BUAH PISANG GOROHO (Musa acuminate) [PDF]
, 2018 AKTIVITAS ANTIFOTOOKSIDASI DAN PENGHAMBATAN PEMBENTUKKAN AGEs (ADVANCED GLYCATION END PRODUCTS) EKSTRAK KULIT BUAH PISANG GOROHO (Musa acuminate)Jane Beatrix Rety Kowaas1), Edi Suryanto2), Defny Silvia Wewengkang3)1)Program studi Farmasi FMIPA Unsrat ...
Kowaas, Jane B.R.
core +1 more source
JSFA reports, EarlyView.Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed +5 more
wiley +1 more source