Results 61 to 70 of about 10,069 (220)

The Role of Lipids in Parkinson’s Disease

Cells, 2019
Parkinson’s disease (PD) is a neurodegenerative disease characterized by a progressive loss of dopaminergic neurons from the nigrostriatal pathway, formation of Lewy bodies, and microgliosis.
Helena Xicoy, Bé Wieringa, Gerard J. M. Martens   +2 more
doaj   +1 more source

HSPE1 deficiency underlies the crosstalk between metabolic dysfunction‐associated steatotic liver disease and age‐related macular degeneration

VIEW, EarlyView.
Rare‐earth ions act as multifunctional modifiers in perovskite solar cells by improving charge transport, suppressing oxygen vacancies, passivating defects, promoting grain growth, and enabling redox‐mediated stabilization. In addition, RE‐doped layers can expand spectral utilization through upconversion and downconversion, thereby enhancing light ...
Jiaqi Meng, Alimire Maihemuti, Yuan Yuan, Chao Chen, Mengchao Zhu, Hao Wang, Furong Zhu, Zhaodi Che, Jia Xiao, Xiangjia Zhu   +9 more
wiley   +1 more source

Biophysical properties of glycerolipids and their impact on membrane architecture and biology

, 2022
International audienceCellular membranes have a remarkable variety of lipids, and different organelles have different lipid compositions. Changes in lipid composition can alter the surface charge, thickness, and fluidity of a membrane characteristics ...
Juliette, Jouhet, Demé Bruno, Bolik Stéphanie, Jouhet Juliette, Stéphanie, Bolik, Bruno, Demé   +5 more
core   +1 more source

Phleum pratense pollen-derived di-galactosyldiacylglycerols promote pro-allergic responses in mice

Frontiers in Immunology
IntroductionGrass pollen triggers nearly 30% of bronchial allergic asthma cases. While most Q8 research focuses on pollen allergens, pollen lipids may also influence allergic reactions.
Nestor González Roldán, Lars P. Lunding, Yukari Fujimoto, Sylvia Düpow, Dominik Schwudke, Dominik Schwudke, Michael Wegmann, Katarzyna A. Duda   +7 more
doaj   +1 more source

Ether glycerolipids: novel substrates for studying specificity of enzymes involved in glycerolipid biosynthesis in higher plants [PDF]

European Journal of Biochemistry, 1985
Ether glycerolipids, predominantly alkylacylglycerols and alkylacylglycerophosphocholines, are synthesized in photomixotrophic rape (Brassica napus) suspension cells from various exogenous monoalkylglycerols. The stereospecific distribution of acyl moieties was studied in these ether glycerolipids with regard to chain‐length and degree of unsaturation ...
N, Weber, H, Benning
openaire   +2 more sources

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

Integrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang, Yonggang Niu, Shengkang Men, Yanghuilin Zhang, Xiaolong Tang, Kenneth B. Storey, Qiang Chen   +6 more
wiley   +1 more source

Stearoyl-CoA desaturase-1 is vital for milk lipid synthesis: Deletion impairs mammary gland and neonatal development

Journal of Lipid Research
The mammary gland synthesizes and secretes nutrient-rich milk containing lactose, protein, and lipids, with the complex assortment of lipids providing more than half of the energy and bioactive factors that impact the growth and development of neonates ...
Mugagga Kalyesubula, Jysiane Cardot, Hailey Huff, Daniel Bergman, Kaitlyn O'Donoghue, Veronica Pegkou Christofi, Kaela Groppel, Lucas M. O'Neill, Lucas Lefers, Jacqueline Rose Miller, Ethan Anderson, Madelaine M. Becker, Dylan Cootway, Joshua Walter, Leriana Garcia Reis, Linda Beckett, Christina R. Ferreira, Catherine Mounier, Isabelle Plante, Theresa M. Casey, James M. Ntambi   +20 more
doaj   +1 more source

Association Characteristics and Potential Mechanisms of Aging, Gut Microbiota, and Hearing Loss

Integrative Zoology, EarlyView.
The study found that aging leads to unchanged gut microbiota alpha diversity but an increase in Bacteroidetes and a decrease in Firmicutes at the phylum level, with specific genera, species, and functional pathways co‐associated with aging and hearing loss. Through constructing a microbe‐metabolite network, it revealed the mechanism by which protective
Cheng Cheng, Lu Wang, Runhan Li, Wenkai Lai, Chongkui Sun, Jianguo Cui, Bicheng Zhu, Jiang Zhang   +7 more
wiley   +1 more source

Mass spectrometric study of the dissociation of Group XI metal complexes with fatty acids and glycerolipids : Ag2H+ and Cu2H+ ion formation in the presence of a double bond

, 2011
Results of mass spectrometric studies are reported for the collisional dissociation of Group XI (Cu, Ag, Au) metal ion complexes with fatty acids (palmitic, oleic, linoleic and a-linolenic) and glycerolipids.
Michael C. Thomas, Blagojevic, V., Sopeia N. Samad, Laura Banu, Blanksby, S.J., Stephen J. Blanksby, Voislav Blagojevic, Banu, L., Thomas, M.C., Bohme, D.K., Diethard K. Bohme, Samad, S.N.   +11 more
core   +1 more source

Genome‐wide association and interaction analysis for proliferative retinopathy in adults with type 2 diabetes born during famine: The DOLCE study in Ukraine

Acta Ophthalmologica, EarlyView.
Abstract Purpose Proliferative diabetic retinopathy (PDR) is one of the leading causes of blindness in working‐age adults. We have previously shown that the risk of PDR is significantly elevated in individuals with intrauterine exposure to famine. However, the genetic mechanisms mediating this association remain unknown.
Olena Fedotkina, Most Champa Begum, Xuan Tung Trinh, Turkuler Özgumus, Mikael Åkerlund, Peter Nilsson, Leticia Maria Spindola, Valeriya Lyssenko   +7 more
wiley   +1 more source