Results 91 to 100 of about 21,259 (271)

Role of Glycerophospholipid Metabolism in Epilepsy

Current Neuropharmacology
Epilepsy is a prevalent and severe neurological condition characterized by recurring seizures. It impacts over 70 million individuals worldwide, posing a substantial challenge to public health and placing a heavy burden on society.
Zijian Li, Zhen Liang, Jing Zhang, Songyan Liu   +3 more
openaire   +2 more sources

Spatial Distribution of Glycerophospholipids in the Ocular Lens

PLoS ONE, 2011
Knowledge of the spatial distribution of lipids in the intraocular lens is important for understanding the physiology and biochemistry of this unique tissue and for gaining a better insight into the mechanisms underlying diseases of the lens. Following our previous study showing the spatial distribution of sphingolipids in the porcine lens, the current
Pól, Jaroslav, Vidová, Veronika, Hyötyläinen, Tuulia, Volný, Michael, Novák, Petr, Strohalm, Martin, Kostiainen, Risto, Havlícek, Vladimír, Wiedmer, Susanne K., Holopainen, Juha, M.   +10 more
openaire   +7 more sources

Bisphenol M Induces Dose‐Dependent Hepatic Injury and Fibrotic Remodeling in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The safety of bisphenol analogs as alternatives to bisphenol A (BPA) is increasingly concerning. This study investigated the hepatotoxic effects of bisphenol M (BPM), a widely used BPA substitute, in 6‐week‐old female BALB/c mice exposed to 2.5, 5, and 10 mg/kg/day intraperitoneally for 14 days. Hepatic changes were assessed via histopathology,
Muhammed Canik, Asuman Deveci Ozkan, Tuğba Kotil, Nazan Deniz Yön   +3 more
wiley   +1 more source

Functional characterization of TMEM86A and TMEM86B mutants by a novel lysoplasmalogenase assay

Journal of Lipid Research
: Plasmalogens are an abundant class of glycero-phospholipids with a characteristic 1-O-alk-1′-enyl double bond. While their synthesis has been extensively investigated, their degradation remains understudied. Plasmalogen deficiencies are associated with
Denise Kummer, Ilaria Dorigatti, Theresia Dunzendorfer-Matt, Georg Golderer, Ernst R. Werner, Katrin Watschinger   +5 more
doaj   +1 more source

PPM1J regulates meat quality feature and glycerophospholipids composition in broiler by modulating protein dephosphorylation

The quality of broiler meat affects consumers’ purchasing decisions. Numerous studies have shown that phosphorylation of proteins in muscle can affect muscle quality. Here, metabolomics and transcriptomics were used to systematically identify the genetic
Yanan Zhang, Xin Yang, Chuntian Zheng, Shuang Wang, Wei Chen, Weiguang Xia, Bolin Cai, Chenglong Jin, Manting Ma   +8 more
core   +1 more source

Synthesis of new caged glycerophospholipids probes

, 2023
La lipidomique a pour but d’étudier le rôle précis de chaque lipide et est un domaine en plein essor. Parmiles lipides, les acides phosphatidiques sont les plus simples des glycérophospholipides et sont un intermédiaire clédans la synthèse des autres ...
Schlichter, Antoine
core  

Additional file 1 of Differences in lipid homeostasis and membrane lipid unsaturation confer differential tolerance to low temperatures in two Cycas species

, 2021
Additional file 1: Table S1. All the identified lipid species in leaves of C. bifida and C. panzhihuaensis. Table S2. The saccharolipids-glycerophospholipids ratio of C. bifida and C. panzhihuaensis treated at low temperature. Table S3.
Yanling Zheng (11283137), Yongqiong Yang (11283140), Zhixiang Yu (11283143), Jianrong Wu (280398), Meng Wang (124646), Shijun Hu (253838)   +5 more
core   +1 more source

Plasma Lipid Remodeling across Preclinical Burden, Disease Onset, and Early Motor Severity in Huntington's Disease

Movement Disorders, EarlyView.
Abstract Background and Objectives Huntington's disease (HD) evolves silently for years before motor onset, yet the systemic metabolic alterations accompanying cumulative exposure to mutant huntingtin and disease progression remain poorly understood.
Mohamed Bendimerad, Dominique Bonneau, Clarisse Scherer‐Gagou, Adriana Prundean, Karim Chikh, Oriane Vitalis, Audrey Olivier, Odile Blanchet, Judith Nzoughet‐Kouassi, Christophe Verny, Pascal Reynier, Juan Manuel Chao de la Barca   +11 more
wiley   +1 more source

Differential Metabolic Dysregulations in Hepatocellular Carcinoma and Cirrhosis: Insights into Lipidomic Signatures

Biomolecules
Hepatocellular carcinoma (HCC), the most common primary liver malignancy, usually develops in patients with cirrhosis, yet the metabolic mechanisms that distinguish the two conditions remain poorly understood.
Cristina-Paula Ursu, Luminița Elena Furcea, Bogdan Procopeț, Răzvan Alexandru Ciocan, Ștefan Ursu, Claudia Diana Gherman, Dan Vălean, Rodica Sorina Pop, Emil Ioan Moiș, Horia Ștefănescu, Carmen Socaciu, Nadim Al Hajjar, Florin Graur   +12 more
doaj   +1 more source

Contribution of glycerophospholipids and sphingomyelin to the circulating NEFA

Prostaglandins, Leukotrienes and Essential Fatty Acids, 2016
Serum nonesterified fatty acids (NEFA) are known to be associated with the development of insulin resistance. Recently, differences in the NEFA profile were found in subjects with history of gestational diabetes (postGDM) and healthy controls. Little is known about the NEFA sources in the postprandial state, which prevails most of the day in humans in ...
Felicitas Maier, Hans Demmelmair, Marina Fugmann, Christian Hellmuth, Andreas Lechner, Berthold Koletzko, Olaf Uhl   +6 more
openaire   +4 more sources