Results 71 to 80 of about 26,416 (261)

Contribution of individual phospholipase A2 enzymes to the cleavage of oxidized phospholipids in human blood plasma

Journal of Lipid Research
Phospholipids containing oxidized esterified PUFA residues (OxPLs) are increasingly recognized for multiple biological activities and causative involvement in disease pathogenesis.
Philipp Jokesch, Olga Oskolkova, Maria Fedorova, Bernd Gesslbauer, Valery Bochkov   +4 more
doaj   +1 more source

Metabolic characterization of the natural progression of chronic hepatitis B [PDF]

, 2016
Background: Worldwide, over 350 million people are chronically infected with the hepatitis B virus (HBV) and are at increased risk of developing progressive liver diseases.
Berger, R. (Ruud), Boonstra, P.A. (André), Hankemeier, T. (Thomas), Harms, A.C. (Amy), Hou, J. (Jun), Schoeman, J.C. (Johannes C.), Vreeken, R. (Rob)   +6 more
core   +1 more source

Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]

, 2020
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana, Guma, Monica, Murillo-Saich, Jessica D   +2 more
core   +2 more sources

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Introduction of a lipidomics scoring system for data quality assessment

Journal of Lipid Research
The scientific field of lipidomics has shown a constantly growing publication number in recent years, which is accompanied by an increasing need for quality standards.
Nils Hoffmann, Robert Ahrends, Erin S. Baker, Kim Ekroos, Xianlin Han, Michal Holčapek, Gerhard Liebisch, Markus R. Wenk, Yu Xia, Harald C. Köfeler   +9 more
doaj   +1 more source

RhoA/Rho Kinase Mediates Neuronal Death Through Regulating cPLA2 Activation [PDF]

, 2016
Activation of RhoA/Rho kinase leads to growth cone collapse and neurite retraction. Although RhoA/Rho kinase inhibition has been shown to improve axon regeneration, remyelination and functional recovery, its role in neuronal cell death remains unclear ...
Eddelman, Daniel B., Lu, Qingbo, Parish, Jonathan M., Walker, Chandler L., Wu, Wei, Wu, Xiangbing, Xu, Xiao-Ming   +6 more
core   +1 more source

Synergistic Enhancement: Whole Wheat Substrate Improves Memory in Mice by Optimizing Folate Metabolism and Systemic Antioxidant Capacity

Food Bioengineering, EarlyView.
ABSTRACT This study rigorously assessed the impact of folic acid‐fortified whole wheat products on mitigating mild liver injury caused by prolonged excessive folic acid consumption, improving folic acid bioavailability, and enhancing spatial cognitive functions in mice over a 48‐day intervention period.
Yan Qi, Songyi Lin, Meina Zhang, Yue Tang   +3 more
wiley   +1 more source

Metabolic lipid alterations in subclinical ketotic dairy cows: A multisample lipidomic approach

Journal of Dairy Science
: Subclinical ketosis (SCK) is a prevalent metabolic disorder in dairy cows during the transition period, characterized by elevated BHB levels without overt clinical symptoms.
Y.R. He, H.Y. Zhao, L.L. Li, J. Tan, Y. Wang, Y.C. Zhao, L.S. Jiang   +6 more
doaj   +1 more source

Metabolic Signatures and Diagnostic Prediction Models for Coronary Artery Disease and Type 2 Diabetes Mellitus: Insights From an Exploratory Study

iNew Medicine, EarlyView.
Metabolomic & lipidomic analysis reveals metabolic overlap between CAD & T2DM, highlighting 7 key metabolites as potential biomarkers. A predictive model based on these achieves high accuracy, potentially advancing precision medicine & metabolic insights.
Zhihua Wang, Meiming Su, Ying Li, Yapei Li, Shuo Chen, Ting Peng, Hans Strijdom, Jiangang Wang, Jianping Weng, Suowen Xu   +9 more
wiley   +1 more source

glycerophospholipids

Citation: 'glycerophospholipids' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09839 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +2 more sources