Results 71 to 80 of about 20,599 (278)

Untargeted metabolomics reveals immune-metabolic signatures in established cases of rheumatoid arthritis

Frontiers in Molecular Biosciences
IntroductionRheumatoid arthritis (RA) is a complex progressive autoimmune disorder wherein chronic inflammation is tightly coupled to metabolic reprogramming. The known diagnostic markers are not sensitive and specific enough to reflect disease activity.
Afshan Masood, Afshan Masood, Reem Almalki, Abeer Malkawi, Maha Al Mogren, Amal Jaafar, Hicham Benabdelkamel, Assim A. Alfadda, Assim A. Alfadda, Assim A. Alfadda, Amina Fallata, Abdurhman S. Alarfaj, Mohamed Siaj, Anas M. Abdel Rahman, Anas M. Abdel Rahman   +14 more
doaj   +1 more source

Novel Intact Polar and Core Lipid Compositions in the Pyrococcus Model Species, P. furiosus and P. yayanosii, Reveal the Largest Lipid Diversity Amongst Thermococcales

Biomolecules, 2020
Elucidating the lipidome of Archaea is essential to understand their tolerance to extreme environmental conditions. Previous characterizations of the lipid composition of Pyrococcus species, a model genus of hyperthermophilic archaea belonging to the ...
Maxime Tourte, Vanessa Kuentz, Philippe Schaeffer, Vincent Grossi, Anais Cario, Philippe M. Oger   +5 more
doaj   +1 more source

Seed lipid profiles of perennial ryegrass: Global patterns and differentiation of ryegrass cultivars and Epichloë endophytes

Grassland Research, EarlyView.
Seed lipid profiles from three ryegrass cultivars infected with AR501 show distinct changes in the medium‐chain diacylglycerols, triacylglycerols and sphingolipids. The differential peal LN745.5052_5.78 can be identified as PG 16:0_18:2 with the supporting ms2 fragmentation spectrum. Abstract Background Forage perennial ryegrass (Lolium perenne L.) has
Mingshu Cao, Wei Zhang, Wade J. Mace, Christine R. Voisey, David E. Hume, Richard D. Johnson, Sushma Prakash   +6 more
wiley   +1 more source

Altered Sphingolipids, Glycerophospholipids, and Lysophospholipids Reflect Disease Status in Idiopathic Steroid-Sensitive Nephrotic Syndrome in Children: A Non-Targeted Metabolomic Study

Cells
Idiopathic steroid-sensitive nephrotic syndrome (ISSNS) is the most common glomerular disease in children, yet its molecular mechanisms and lipid-mediated pathophysiology remain poorly understood.
Takahiro Kanai, Hideo Ogiso, Jun Aoyagi, Masanori Kurosaki, Tomomi Maru, Marika Ishii, Kazuya Tanimoto, Mitsuaki Yoshino, Yuri Yamashita, Toshihiro Tajima, Ryozo Nagai, Kenichi Aizawa   +11 more
doaj   +1 more source

Lipidomic analysis of urinary exosomes from hereditary α‐tryptasemia patients and healthy volunteers

FASEB BioAdvances, 2019
Exosomes are nano‐sized vesicles that are involved in various biological processes including cell differentiation, proliferation, signaling, and intercellular communication.
Sarah C. Glover, Mohammad‐Zaman Nouri, Kubra M. Tuna, Lybil B. Mendoza Alvarez, Lisa K. Ryan, James F. Shirley, Ying Tang, Nancy D. Denslow, Abdel A. Alli   +8 more
doaj   +1 more source

Composition of glycerophospholipids from the hydrocorals Millepora platyphylla and M. dichotoma.

, 2019
Composition of glycerophospholipids from the hydrocorals Millepora platyphylla and M. dichotoma.
Andrey B. Imbs (6645782), Ly P. T. Dang (6645785), Kien B. Nguyen (6645788)   +2 more
core   +1 more source

Gut microbiome seasonality is associated with dietary plasticity and coexistence in three sympatric Pamir ungulates

iMetaOmics, EarlyView.
This graphical abstract outlines a multi‐omics framework investigating the seasonal dietary composition and gut microbial communities of three coexisting ungulate species inhabiting the extreme high‐altitude Pamir Plateau (Ovis ammon polii, Capra sibirica, and Pseudois nayaur). By integrating dietary DNA metabarcoding, 16S rRNA gene sequencing, shotgun
Dilala Tuoliu, Lijiao Zhang, Muyang Wang, Wenxuan Xu, Kathreen Ruckstuhl, António Alves da Silva, Joana Alves, Hongchen Jiang, Weikang Yang   +8 more
wiley   +1 more source

Lipid Subclasses Differentiate Insulin Resistance by Triglyceride–Glucose Index

Metabolites
Background: Insulin resistance is a key driver of metabolic syndrome and related disorders, yet its underlying metabolic alterations remain incompletely understood.
Khaled Naja, Najeha Anwardeen, Omar Albagha, Mohamed A. Elrayess   +3 more
doaj   +1 more source

Spatial Distribution of Glycerophospholipids in the Ocular Lens

PLoS ONE, 2011
Knowledge of the spatial distribution of lipids in the intraocular lens is important for understanding the physiology and biochemistry of this unique tissue and for gaining a better insight into the mechanisms underlying diseases of the lens. Following our previous study showing the spatial distribution of sphingolipids in the porcine lens, the current
Pól, Jaroslav, Vidová, Veronika, Hyötyläinen, Tuulia, Volný, Michael, Novák, Petr, Strohalm, Martin, Kostiainen, Risto, Havlícek, Vladimír, Wiedmer, Susanne K., Holopainen, Juha, M.   +10 more
openaire   +7 more sources

Image5_Plasmalogens, the Vinyl Ether-Linked Glycerophospholipids, Enhance Learning and Memory by Regulating Brain-Derived Neurotrophic Factor.TIF

, 2022
Plasmalogens (Pls), a kind of glycerophospholipids, have shown potent biological effects but their role in hippocampus-dependent memory remained mostly elusive.
Shiro Mawatari (12062999), Takehiko Fujino (12063002), Md. Shamim Hossain (12062996)   +2 more
core   +1 more source