Glycitein alleviates inflammation and apoptosis in keratinocytes via ROS-associated PI3K–Akt signalling pathway [PDF]
Open Life SciencesAbstract A chronic inflammatory skin disorder, psoriasis, affects 2–3% of people worldwide. A bioactive substance, glycitein (GCN), has several pharmacological characteristics. This work aims to evaluate the effects of GCN on the in vitro proliferation and death of human HaCaT keratinocytes.
Sun Wenqian +3 more
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Lifestyle Genomics, 2022 Introduction: The prevalence of colon cancer remains high across the world. The early diagnosis of colon cancer is challenging. Moreover, patients with colon cancer frequently suffer from poor prognoses.
Tao Xiang, Weibiao Jin
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Glycitin in Soy Beans: A Mine of Their Structures, Functions, and Potential Applications [PDF]
FoodsGlycitin is a kind of compound found in soybeans that has attracted increasing attention as a good source of nutrients due to its potential applications in medicine, cosmetics, and food.
Hongqiang Wu +3 more
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Computational-experimental study reveals direct target and bioactives of Ajania fruticulosa against NAFLD via TLR2/NF-κB/PPAR-γ signaling [PDF]
npj Science of FoodNon-alcoholic fatty liver disease (NAFLD) is a prevalent metabolic disorder with limited treatment options. This study investigated the therapeutic potential of water extract of Ajania fruticulosa (WEAF) against NAFLD in cellular and animal models.
Chaoyue Chen +13 more
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Accessing Citrus and Soybean Flavonoids as Potential Efflux Pump Inhibitors in Drug-Resistant Escherichia coli [PDF]
AntibioticsBackground/Objectives: Drug efflux pumps represent a significant challenge that contributes to the development of antibiotic resistance in bacteria. This research aimed to evaluate the flavonoids apigenin, chrysin, glycitein, and hesperetin for their ...
Wen-Jung Lu +3 more
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Functional analysis of type II chalcone isomerase (CHI) genes in regulating soybean (Glycine max L.) nodule formation [PDF]
GM Crops & FoodBiological nitrogen fixation (BNF) is the most cost-effective and environmentally benign method for nitrogen fertilization. Isoflavones are important signaling factors for BNF in leguminous plants. Whether chalcone isomerase (CHI), the key enzyme gene in
Xinyue Wang +9 more
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Dietary Flavonoid Intake and Risk of Mild Cognitive Impairment in the Elderly: A Case-Control Study [PDF]
Nutrition and Metabolic InsightsBackground: This study investigates the association between dietary flavonoid intake and the incidence of mild cognitive impairment (MCI) through a matched case-control design.
Quanri Liu +6 more
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Frontiers in Nutrition, 2023 IntroductionPrediabetes is a metabolic condition characterized by blood glucose levels that are higher than normal but do not meet the threshold for a diabetes diagnosis. Individuals with prediabetes are at an increased risk of developing type 2 diabetes
Yanjun Zhou +4 more
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Agriculture, 2021 This study was carried out to investigate the variations in protein and isoflavone contents of 300 soybean germplasms introduced from domestic and foreign countries and to compare their contents in terms of size, colour and country of origin. The protein
Ji-Seok Lee +2 more
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High dietary daidzein intake lowers cholesterol levels among post-menopausal women
Universa Medicina, 2020 Background Menopause is associated with changes in metabolic profile. Although hormone replacement therapy (HRT) has been shown to have beneficial effects on lipid metabolism, its adverse effects have indicated a need for alternative estrogen-based ...
Elly Herwana +2 more
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