The synthesis of [2,3,4-13C3]glycitein
Glycitein is one of the soy isoflavones which have attracted considerable interest in recent years due to their possible beneficial effects on human health. However, glycitein has been much less studied than other members of this family due to the lack of good methods for its synthesis. Herein we report a short high yielding synthesis of a multiply 13C-
Qingzhi Zhang, Nigel P. Botting
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Glycitein alleviates inflammation and apoptosis in keratinocytes via ROS-associated PI3K–Akt signalling pathway [PDF]
Abstract A chronic inflammatory skin disorder, psoriasis, affects 2–3% of people worldwide. A bioactive substance, glycitein (GCN), has several pharmacological characteristics. This work aims to evaluate the effects of GCN on the in vitro proliferation and death of human ...
Sun Wenqian +3 more
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Metabolism of Glycitein (7,4‘-Dihydroxy-6-methoxy-isoflavone) by Human Gut Microflora [PDF]
Gut microbial disappearance and metabolism of the soy isoflavone glycitein, 7,4'-dihydroxy-6-methoxyisoflavone, were investigated by incubating glycitein anaerobically with feces from 12 human subjects. The subjects' ages ranged from 24 to 53 years with a body mass index (BMI) of 20.9-25.8 kg/m(2) (mean BMI = 24.0 +/- 1.1 kg/m(2)).
Simons, Andrean +3 more
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Computational-experimental study reveals direct target and bioactives of Ajania fruticulosa against NAFLD via TLR2/NF-κB/PPAR-γ signaling [PDF]
Non-alcoholic fatty liver disease (NAFLD) is a prevalent metabolic disorder with limited treatment options. This study investigated the therapeutic potential of water extract of Ajania fruticulosa (WEAF) against NAFLD in cellular and animal models.
Chaoyue Chen +13 more
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Glycitin in Soy Beans: A Mine of Their Structures, Functions, and Potential Applications [PDF]
Glycitin is a kind of compound found in soybeans that has attracted increasing attention as a good source of nutrients due to its potential applications in medicine, cosmetics, and food.
Hongqiang Wu +3 more
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Cytochrome GmGLY1 is Involved in the Biosynthesis of Glycitein in Soybean
Isoflavones, the major secondary metabolites of interest due to their benefits to both human and plant health, are exclusively produced by legumes. In this study, we profiled the isoflavone content in dry seeds from 211 soybean [Glycine max (L.) Merr.] accessions grown across five environments.
Peipei Zhang +8 more
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Accessing Citrus and Soybean Flavonoids as Potential Efflux Pump Inhibitors in Drug-Resistant Escherichia coli [PDF]
Background/Objectives: Drug efflux pumps represent a significant challenge that contributes to the development of antibiotic resistance in bacteria. This research aimed to evaluate the flavonoids apigenin, chrysin, glycitein, and hesperetin for their ...
Wen-Jung Lu +3 more
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Collected literature on isoflavones and chronic diseases
Isoflavones are organic compounds, which have been linked to the health benefits and prevention of many diseases. Common isoflavones are genistein, daidzein, and glycitein.
Katie A. Miller +5 more
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CHAPTER 28. Glycitein in Health
Glycitein is the third most abundant isoflavone found in soy. While there is a link between isoflavone consumption and improved health, there is gap in understanding how glycitein itself and glycitein-rich foods influence human health. While the majority of research in the area of soy and health has focused on genistein and daidzein, this Chapter will ...
Brian R. Stephens, Joshua A. Bomser
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vi GENERAL INTRODUCTION 1 A. Introduction 1 B. Dissertation Organization 3 LITERATURE REVIEW 4 A. Plant Sources and Analytical Chemistry of Isoflavones 4 B. Sources of Isoflavone Standards: Isolation. Purification and ChemicalSynthesis 15 C. How Do Plants Make Isoflavones? 17 D. .Are Isoflavones Good Antioxidants? 19 E. Estrogenic or Antiestrogenic? 21
Song, Tongtong
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