Results 21 to 30 of about 4,293 (152)

Monoclonal Antibody AP3 Binds Galactomannan Antigens Displayed by the Pathogens Aspergillus flavus, A. fumigatus, and A. parasiticus

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
Aspergillus fumigatus and A. flavus are the fungal pathogens responsible for most cases of invasive aspergillosis (IA). Early detection of the circulating antigen galactomannan (GM) in serum allows the prompt application of effective antifungal therapy ...
Max Schubert   +9 more
doaj   +1 more source

Marine Glycobiology: Current Status and Future Perspectives

open access: yes
Glycobiology, which is the study of the structure and function of carbohydrates and carbohydrate containing molecules, is fundamental to all biological systems. Progress in glycobiology has shed light on a range of complex biological processes associated
Pagett HE, Caldwell GS
core   +4 more sources

Yeast Mnn9 is both a priming glycosyltransferase and an allosteric activator of mannan biosynthesis [PDF]

open access: yesOpen Biology, 2013
The fungal cell possesses an essential carbohydrate cell wall. The outer layer, mannan, is formed by mannoproteins carrying highly mannosylated O- and N-linked glycans. Yeast mannan biosynthesis is initiated by a Golgi-located complex (M-Pol I) of two GT-
Alexander Striebeck   +3 more
doaj   +1 more source

Using graph convolutional neural networks to learn a representation for glycans

open access: yesCell Reports, 2021
Summary: As the only nonlinear and the most diverse biological sequence, glycans offer substantial challenges for computational biology. These carbohydrates participate in nearly all biological processes—from protein folding to viral cell entry—yet are ...
Rebekka Burkholz   +2 more
doaj   +1 more source

An interactive and integrative view of glycobiology

open access: yes, 2018
Glycosylation is one of the most abundant post-translational modifications (PTM) and the primary cause of microheterogeneity in proteins (glycoforms). It consists of the addition of a sugar moiety on the surface of a protein, and it has been suggested ...
Alocci, Davide
core   +1 more source

A Review of Sex Differences: Glycobiology and Immunology [PDF]

open access: yes, 2021
The biological differences between males and females are significant yet too often overlooked. In research and clinical studies, sex differences are often not taken into consideration. However, glycobiology and immunology are starting to shift.
Katie Walline, Lisa Willis
core   +1 more source

The Glycoprotease CpaA Secreted by Medically Relevant Acinetobacter Species Targets Multiple O-Linked Host Glycoproteins

open access: yesmBio, 2020
Glycans decorate proteins and affect their biological function, including protection against proteolytic degradation. However, pathogenic, and commensal bacteria have evolved specific glycoproteases that overcome the steric impediment posed by ...
M. Florencia Haurat   +7 more
doaj   +1 more source

Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin

open access: yesmBio, 2022
Typhoid toxin is an A2B5 protein toxin and an important virulence factor for the human-adapted bacterial pathogen Salmonella enterica serovar Typhi, the causative agent of typhoid fever. Typhoid toxin contains two enzymatic subunits, PltA and CdtB, which
Xiaoyu Liu   +9 more
doaj   +1 more source

The glycan fingerprint in immune thrombocytopenia

open access: yesResearch and Practice in Thrombosis and Haemostasis
A state-of-the-art lecture titled “Platelet Glycobiology and Immune Thrombocytopenia (ITP)” was presented at the International Society on Thrombosis and Haemostasis (ISTH) congress in 2025.
Vivianne S. Nelson   +2 more
doaj   +1 more source

Recent Developments in the Use of Glyconanoparticles and Related Quantum Dots for the Detection of Lectins, Viruses, Bacteria and Cancer Cells

open access: yesFrontiers in Chemistry, 2021
Carbohydrate-coated nanoparticles—glyconanoparticles—are finding increased interest as tools in biomedicine. This compilation, mainly covering the past five years, comprises the use of gold, silver and ferrite (magnetic) nanoparticles, silicon-based and ...
Pedro J. Hernando   +5 more
doaj   +1 more source

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