Results 41 to 50 of about 4,293 (152)
Cancer's sweet spot: techniques to harness saccharides in tumor biology
BioTechniquesAll of the cells in our bodies are enveloped in sugar, this sweet coating plays a particularly interesting and crucial role in tumor biology. Here, we review the techniques being used to detect and exploit cancer's sweet spot.
Jade Parker
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Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Laminarin Quantification in Microalgae with Enzymes from Marine Microbes
Bio-Protocol, 2018 The marine beta-glucan laminarin is an abundant storage polysaccharide in microalgae. High production rates and rapid digestion by heterotrophic bacteria turn laminarin into an ideal carbon and energy source, and it is therefore a key player in the ...
Stefan Becker, Jan-Hendrik Hehemann
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The Crossroads of Glycoscience, Infection, and Immunology
Frontiers in Microbiology, 2021 Advances in experimental capabilities in the glycosciences offer expanding opportunities for discovery in the broad areas of immunology and microbiology.
Tanya R. McKitrick +12 more
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Databases and Bioinformatic Tools for Glycobiology and Glycoproteomics
, 2020 Glycosylation plays critical roles in various biological processes and is closely related to diseases. Deciphering the glycocode in diverse cells and tissues offers opportunities to develop new disease biomarkers and more effective recombinant ...
Xiaokun Hong +4 more
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Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes
The FEBS Journal, EarlyView.C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli +6 more
wiley +1 more source
Significance of β-Galactoside α2,6 Sialyltranferase 1 in Cancers
Molecules, 2015 Altered glycosylation is a common feature of cancer cells. It takes a variety of forms, which includes loss of expression or excessive expression of some structures, the accumulation of precursors, the appearance of novel structures, etc.
Jishun Lu, Jianguo Gu
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Plant Biotechnology Journal, EarlyView.ABSTRACT Plant cell walls are polysaccharide‐rich extracellular matrices composed of multiple complex carbohydrate polymer networks, including cellulose, hemicelluloses, pectins, and glycosylated proteins. Polysaccharide deposition critically impacts cell wall structure, and structural microheterogeneity within cell wall glycans also influences polymer
C. Frankie Griffith +2 more
wiley +1 more source
mBio, 2019 Neisseria gonorrhoeae is a significant threat to global health for which a vaccine and novel treatment options are urgently needed. Glycans expressed by human cells are commonly targeted by pathogens to facilitate interactions with the host, and thus ...
Evgeny A. Semchenko +5 more
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