Results 61 to 70 of about 4,293 (152)

The Minimum Information Required for a Glycomics Experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data [PDF]

, 2016
MIRAGE (Minimum Information Required for A Glycomics Experiment) is an initiative that was created by experts in the fields of glycobiology, glycoanalytics, and glycoinformatics to produce guidelines for reporting results from the diverse types of ...
Costello, Catherine E, McBride, R., York, W., Paulson, J. C., Costello, C., Palma, A., Khoo, K-H, Dell, A., York, WS, Kolarich, D., McBride, Ryan, Karlsson, Niclas G, Packer, NH, Campbell, Matthew P, Palma, AS, Packer, N. H., Costello, CE, Zaia, J, Wells, L, Liu, Y, Feizi, Ten, Tiemeyer, M., Silva, L., Agravat, S., Rudd, Pauline M, Paulson, J., Zaia, J., Khoo, K., Costello, C. E., Smith, David F, Kettner, Carsten, Agravat, S, Novotny, M. V., Paulson, JC, Stoll, M., Packer, N., Struwe, Weston B, Feizi, T., Novotny, M., McBride, R, Paulson, James C, Karlsson, N., Rudd, P., Smith, DF, Dell, A, Agravat, Sanjay, Stoll, M, Silva, Lisete, Smith, D. F., Novotny, M, Wells, L., Haslam, S. M., Struwe, W., Palma, A. S., Haslam, Stuart M, Karlsson, NG, Smith, D., Aoki-Kinoshita, K. F., York, W. S., Khoo, Kay-Hooi, Kolarich, D, Kettner, C., Rudd, PM, Campbell, MP, Ranzinger, R., Struwe, WB, Kettner, C, Aoki-Kinoshita, K., Campbell, M. P., Rudd, P. M., Tiemeyer, M, Campbell, M., Liu, Yan, Silva, L, Packer, Nicolle H, Aoki-Kinoshita, KF, Rapp, E., Khoo, K. H., Struwe, W. B., Rapp, E, Dell, Anne, Rapp, Erdmann, Ranzinger, R, Novotny, Milos V, Kolarich, Daniel, Aoki-Kinoshita, Kiyoko F, Haslam, SM, Tiemeyer, Michael, York, William S, Ranzinger, Rene, Stoll, Mark, Feizi, T, Karlsson, Niclas G.,, Wells, Lance, Liu, Y., Palma, Angelina S, Haslam, S., Zaia, Joseph   +97 more
core   +1 more source

Status Quo of Glycosylation in Cancer: What Is, What Is Not and What Is to Be

Applied Sciences, 2020
Glycobiology is gaining paramount importance for its influence on diseases as a consequence of a fundamental understanding of the underlying processes involved in them.
Manikandan Muthu, Judy Gopal, Sechul Chun, Anna Jacintha Prameela Devadoss, Jae-Wook Oh   +4 more
doaj   +1 more source

Encoding Cell‐Surface Receptor Function Through Glycosylation: Lessons From CD44

ChemBioChem, Volume 27, Issue 19, 14 October 2026.
CD44 function is not solely determined by its protein sequence, it is dynamically encoded by its glycosylation state. Glycan remodeling generates distinct functional receptor states that regulate ligand recognition, receptor organization, lectin interactions, and signaling.
María Payá‐García, José Manuel Rojas‐Marcos, Iris A. Bermejo, Diego Del Balzo, Ana Ardá, Luca Unione, Jesús Jiménez‐Barbero, Ana Gimeno   +7 more
wiley   +1 more source

Structural basis for mammalian nucleotide sugar transport

eLife, 2019
Nucleotide-sugar transporters (NSTs) are critical components of the cellular glycosylation machinery. They transport nucleotide-sugar conjugates into the Golgi lumen, where they are used for the glycosylation of proteins and lipids, and they then ...
Shivani Ahuja, Matthew R Whorton
doaj   +1 more source

High-throughput glycoanalytical technology for systems glycobiology

, 2010
The development of glycoanalytical HPLC-based high-throughput technology has greatly enhanced the study of glycobiology, facilitating the discovery of disease-related solutions and providing an informative view of glycosylation and its relationship with ...
Li Liu, Pauline M. Rudd, Ana Knezevic, Jayne E. Telford   +3 more
core   +1 more source

Deep Learning Prediction of O‐Glycopeptide Tandem Mass Spectra Enhances O‐Glycoproteomics

Advanced Science, Volume 13, Issue 58, 19 October 2026.
DeepGPO integrates Transformer and graph neural networks with tailored training strategies, including data augmentation, loss re‐weighting, and pre‐training, to achieve high‐quality O‐glycopeptide MS/MS spectra prediction. The predicted MS/MS spectra are used to localize O‐glycosylation sites from HCD MS/MS data, enhancing O‐glycoproteomics analysis ...
Yu Zong, Yuxin Wang, Liang Qiao
wiley   +1 more source

NMR in microbial glycobiology

, 2023
The mini-symposium on NMR in microbial glycobiology is organized as the final event of the bilateral project BI-IT-18-20-006: »Mechanism of KKP lectin targeting biofilm of pathogenic and probiotic bacteria«, led by Prof. Dr.

core  

Hepatocyte Growth Hormone Receptor Ablation Is Associated With Aging Phenotypes and Hepatic Mitochondrial Dysfunction

Aging Cell, Volume 25, Issue 10, October 2026.
Hepatocyte‐specific GHR ablation is associated with hepatic and age‐related pathologies, triggering adipose‐liver crosstalk via elevated circulating GH and subsequent CD36‐dependent hepatic steatosis. This loss impairs STAT5b phosphorylation and enhances PPARγ nuclear activation, upregulating Pdk4 and Cd36 to drive mitochondrial dysfunction and ectopic
Kangkang Yang, Yuli Jian, Fusheng Pang, Ming Ying, Qian Yang, Nian Liu, Shujing Wang, Yingjie Wu   +7 more
wiley   +1 more source

Discovery of Serotransferrin Glycoforms: Novel Markers for Diagnosis of Liver Periductal Fibrosis and Prediction of Cholangiocarcinoma

Biomolecules, 2019
Cholangiocarcinoma (CCA) caused by chronic liver fluke infection is a major public health problem in Northeast Thailand. Identification of CCA risk groups is urgently needed for the control of CCA in this region.
Wassana Jamnongkan, Carlito B. Lebrilla, Mariana Barboza, Anchalee Techasen, Watcharin Loilome, Paiboon Sithithaworn, Narong Khuntikeo, Chawalit Pairojkul, Nittaya Chamadol, Raynoo Thanan, Puangrat Yongvanit   +10 more
doaj   +1 more source

Targeting cancer-associated glycans as a therapeutic strategy in leukemia

All Life, 2022
Unlike cytotoxic chemotherapy, cancer immunotherapy offers targeted therapies that exploit the effector mechanisms of the immune system to combat cancer.
Ashraf Abdullah Saad
doaj   +1 more source