Results 121 to 130 of about 7,626 (185)

Creating unimolecular multivalent diversity in protein conjugates via the Passerini multicomponent bioconjugation with isocyanoproteins. [PDF]

open access: yesCommun Chem
Humpierre AR   +11 more
europepmc   +1 more source

Distinct effects of adjuvants on B cell responses to protein or polysaccharide antigens contained in glycoconjugate vaccines. [PDF]

open access: yesFront Immunol
Budroni S   +13 more
europepmc   +1 more source

Glycoconjugate glycosyltransferases

Glycoconjugate Journal, 2008
Assay methods for representative glycosyltransferases were described, covering those involved in the synthesis of glycosphingolipids, N-glycans, O-glycans, and proteoglycan glycosaminoglycans. In addition, intracellular localization of glycosyltransferase was comprehensively summarized.
Koichi, Furukawa   +3 more
openaire   +2 more sources

Microbial glycoconjugates

Current Opinion in Structural Biology, 1998
The surfaces of all microbes are 'sugar coated' with molecules such as lipopolysaccharides in Gram-negative bacteria, capsular polysaccharides in bacteria, lipoarabinomannans in mycobacteria and lipophosphoglycan in Leishmania. The basic structures of these glycoconjugates are known and, in the case of pathogens, they can function as virulence ...
B J, Mengeling, S J, Turco
openaire   +2 more sources

Glycoconjugate vaccines

Expert Opinion on Biological Therapy, 2012
The global disease burden of serious bacterial infections is caused mainly by Haemophilus influenzae type b (Hib), Streptococcus pneumoniae and Neisseria meningitidis. Death or disability may be the potential aftermath of invasive infections with these pathogens.
openaire   +2 more sources

Glycoconjugates in Cancer Therapy

Anti-Cancer Agents in Medicinal Chemistry, 2008
This review focuses on recent efforts in glycoconjugate construction for the creation and evaluation of vaccines based on carbohydrate cancer-associated antigens. This therapeutic approach takes advantage from the known tendency of transformed cells to express selective carbohydrate motifs otherwise hidden in normal cells. The immunological response is
CIPOLLA, LAURA FRANCESCA   +2 more
openaire   +2 more sources

The remodeling of glycoconjugates in mice

Biochimica et Biophysica Acta (BBA) - General Subjects, 1999
A role for glycoconjugates in mediating cellular interactions is well established. To further understand the formation, function and regulation of various glycoconjugates in vivo, gene targeting approaches have been applied to glycosyltransferase and glycosidase enzymes involved in different biosynthetic pathways.
Hennet T, Ellies LG
openaire   +3 more sources

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