Results 41 to 50 of about 448,615 (401)

Separation and Characterisation of Glycogen Synthase Kinase 3,Glycogen Synthase Kinase 4 and Glycogen Synthase Kinase 5 from Rabbit Skeletal Muscle [PDF]

open access: yesEuropean Journal of Biochemistry, 1982
Three glycogen synthase kinases termed glycogen synthase kinase 3, glycogen synthase kinase 4 and glycogen synthase kinase 5, which are distinct from cyclic‐AMP‐dependent protein kinase and phosphorylase kinase,have been purified and characterised. Their activities are unaffected by Ca2+, calmodulin, cyclic nucleotides and the inhibitor protein of ...
Cohen P   +5 more
openaire   +3 more sources

Islet Transplantation under the Kidney Capsule Corrects the Defects in Glycogen Metabolism in Both Liver and Muscle of Streptozocin-Diabetic Rats

open access: yesCell Transplantation, 2002
Insulin-deficient rats are characterized by multiple defects in the pathway of glycogen synthesis and breakdown in both liver and skeletal muscle. The aim of this study was to clarify whether islet transplantation under the kidney capsule, which is ...
Margherita Matarazzo   +7 more
doaj   +1 more source

Cereal and nonfat milk support muscle recovery following exercise [PDF]

open access: yes, 2009
All authors are with the Exercise Physiology and Metabolism Laboratory Department of Kinesiology and Health Education The University of Texas at Austin Austin, TX, USABackground: This study compared the effects of ingesting cereal and nonfat milk (Cereal)
Ding, Zhenping   +5 more
core   +3 more sources

Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux

open access: yesCell Death and Disease, 2018
Healthy neurons do not store glycogen while they do possess the machinery for the glycogen synthesis albeit at an inactive state. Neurons in the degenerating brain, however, are known to accumulate glycogen, although its significance was not well ...
Anupama Rai   +9 more
semanticscholar   +1 more source

Local anaesthetic bupivacaine induced ovarian and prostate cancer apoptotic cell death and underlying mechanisms in vitro [PDF]

open access: yes, 2016
Retrospective studies indicate that the use of regional anesthesia can reduce cancer recurrence after surgery which could be due to ranging from immune function preservation to direct molecular mechanisms.
Chen, L   +5 more
core   +8 more sources

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

open access: yesHepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario   +12 more
wiley   +1 more source

ATP synthase: evolution, energetics, and membrane interactions [PDF]

open access: yesJ Gen Physiol. 2020 Nov 2;152(11):e201912475, 2020
The synthesis of ATP, life's 'universal energy currency', is the most prevalent chemical reaction in biological systems, and is responsible for fueling nearly all cellular processes, from nerve impulse propagation to DNA synthesis. ATP synthases, the family of enzymes that carry out this endless task, are nearly as ubiquitous as the energy-laden ...
arxiv   +1 more source

Starch biogenesis: relationship between starch structures and starch biosynthetic enzymes [PDF]

open access: yes, 2006
The goal of this research is to gain understanding on starch biogenesis by studying starch granule formation and development. The objectives of this research were to modify the structure of cyanobacteria glycogen by replacing the endogenous glycogen ...
Li, Li
core   +2 more sources

In vivo regulation of glycogen synthase kinase 3β activity in neurons and brains

open access: yesScientific Reports, 2017
Glycogen synthase kinase 3β (GSK3β) is a multifunctional protein kinase involved in many cellular activities including development, differentiation and diseases.
Ambika Krishnankutty   +9 more
semanticscholar   +1 more source

Destabilization of mutated human PUS3 protein causes intellectual disability

open access: yesHuman Mutation, Volume 43, Issue 12, Page 2063-2078, December 2022., 2022
The homodimer of pseudouridine synthase 3 converts uridines at position 39 in tRNAs to pseudouridine (ψ), which affects tRNA stability and regulates RNA–protein interactions. Several patient‐derived variants of PUS3 have been associated with neurodegenerative diseases.
Ting‐Yu Lin   +17 more
wiley   +1 more source

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