Results 31 to 40 of about 98,730 (257)

The Stimulation of Glycogen Synthesis and of Glycogen Synthetase in the Liver by the Administration of Glucose [PDF]

European Journal of Biochemistry, 1967
The intravenous administration of glucose to the mouse stimulates 15–20 and up to 40‐fold the conversion of glucose to glycogen in the liver. This effect is observed in the normally fed as well as in the fasted animal and requires 5 min to reach its full development. At that time, the hepatic concentration of glucose 6‐phosphate and of UDPG is markedly
H, De Wulf, H G, Hers
openaire   +2 more sources

Identification of the Genes Related to the Glycogen Metabolism in Hyperthermophilic Archaeon, Sulfolobus acidocaldarius

Frontiers in Microbiology, 2021
Glycogen is a polysaccharide that comprises α-1,4-linked glucose backbone and α-1,6-linked glucose polymers at the branching points. It is widely found in organisms ranging from bacteria to eukaryotes.
Areum Lee, Eunji Bae, Jihee Park, Kyoung-Hwa Choi, Jaeho Cha, Jaeho Cha   +5 more
doaj   +1 more source

Shared control of hepatic glycogen synthesis by glycogen synthase and glucokinase [PDF]

Biochemical Journal, 2000
We have used recombinant adenoviruses (AdCMV-RLGS and AdCMV-GK) to overexpress the liver isoforms of glycogen synthase (GS) and glucokinase (GK) in primary cultured rat hepatocytes. Glucose activated overexpressed GS in a dose-dependent manner and caused the accumulation of larger amounts of glycogen in the AdCMV-RLGS-treated hepatocytes.
R R, Gomis, J C, Ferrer, J J, Guinovart
openaire   +2 more sources

The Protein Phosphatase 1 Complex Is a Direct Target of AKT that Links Insulin Signaling to Hepatic Glycogen Deposition

Cell Reports, 2019
Summary: Insulin-stimulated hepatic glycogen synthesis is central to glucose homeostasis. Here, we show that PPP1R3G, a regulatory subunit of protein phosphatase 1 (PP1), is directly phosphorylated by AKT.
Qiqi Li, Qiuye Zhao, Junyu Zhang, Linkang Zhou, Wenhao Zhang, BoonTin Chua, Yan Chen, Li Xu, Peng Li   +8 more
doaj   +1 more source

A Missing Step in Glycogen Synthesis

The Scientific World JOURNAL, 2002
INTRODUCTION. There is strong evidence for the existence of a discrete intermediate in glycogen (macroglycogen) synthesis. This has been termed proglycogen[1]. It is narrowly disperse and has a mass of about 400kDa. Containing 10% by weight of the glycogen primer, the self-glucosylating glycogenin, proglycogen is separable from macroglycogen by the ...
Mari Dei Park, Melissa Debayle, William J. Whelan, Erik Barquist, Yoram Klein   +4 more
openaire   +3 more sources

Allosteric Regulation of Glycogen Synthase Controls Glycogen Synthesis in Muscle [PDF]

Cell Metabolism, 2010
Glycogen synthase (GS), a key enzyme in glycogen synthesis, is activated by the allosteric stimulator glucose-6-phosphate (G6P) and by dephosphorylation through inactivation of GS kinase-3 with insulin. The relative importance of these two regulatory mechanisms in controlling GS is not established, mainly due to the complex interplay between multiple ...
Bouskila, Michale, Hunter, Roger W., Ibrahim, Adel F.M., Delattre, Lucie, Peggie, Mark, Van Diepen, Janna A., Voshol, Peter J., Jensen, Jørgen, Sakamoto, Kei   +8 more
openaire   +4 more sources

Characterization of glycogen-related glycoside hydrolase glgX and glgB from Klebsiella pneumoniae and their roles in biofilm formation and virulence

Frontiers in Cellular and Infection Microbiology
Glycogen is a polymer used by bacteria to store excess glucose, playing a crucial role in bacterial growth, stress resistance, biofilm formation, and virulence.
Xinyue Liu, Xinyue Liu, Jialin Li, Ruibing Wu, Liping Bai   +4 more
doaj   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Glycogen synthase activity in Candida albicans is partly controlled by the functional ortholog of Saccharomyces cerevisiae Gac1p

mSphere
To adapt to various host microenvironments, the human fungal pathogen Candida albicans possesses the capacity to accumulate and store glycogen as an internal carbohydrate source.
Jian Miao, David L. Williams, Michael D. Kruppa, Brian M. Peters   +3 more
doaj   +1 more source

Evaluation of possible mechanisms of three plants for blood glucose control in diabetes

Bangladesh Journal of Pharmacology, 2016
This study was conducted to provide the evidence for the mechanism of  anti-diabetic activity of Cocculus orbiculatus, Leea indica and Ventilago maderaspatana.
Damayanthi Dalu, Satyavati Dhulipala
doaj   +1 more source