Results 1 to 10 of about 81,425 (291)

α-Lactosylceramide Protects Against iNKT-Mediated Murine Airway Hyperreactivity and Liver Injury Through Competitive Inhibition of Cd1d Binding [PDF]

Frontiers in Chemistry, 2019
Invariant natural killer T (iNKT) cells, which are activated by T cell receptor (TCR)-dependent recognition of lipid-based antigens presented by the CD1d molecule, have been shown to participate in the pathogenesis of many diseases, including asthma and ...
Alan Chuan-Ying Lai, Po-Yu Chi, Christina Li-Ping Thio, Yun-Chiann Han, Hsien-Neng Kao, Hsiao-Wu Hsieh, Jacquelyn Gervay-Hague, Ya-Jen Chang   +7 more
doaj   +3 more sources

Crossing the metabolic homeostasis divide: panoramic decoding of therapeutic targets for metabolic-inflammatory crosstalk in rheumatoid arthritis [PDF]

Frontiers in Immunology
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and joint destruction. Its pathogenesis is closely related to the imbalance of glycolipid metabolism.
Siyu Liang, Siyu Liang, Lei Wan, Siyu Wang, Mengyu Zhang, Ying Wang, Wenwen Min, Yu Zhang   +7 more
doaj   +2 more sources

Optimization of the slaughterhouse water treatment rate by a new Marinobacter carbonoclasticus SF and its biosurfactant [PDF]

Journal of the Serbian Chemical Society, 2022
The aim of this study consists of the production of a bio-surfactant from a new bacterial strain, Marinobacter hydrocarbono clasticus SF (96.76 % similarity) isolated from soil contaminated by hydrocarbons in Hassi-Messaoud (Southern Algeria) to treat ...
Mihoubi Nadia, Ferhat Samira, Alouaoui Redha, Ibrir Abdellah, Nedjhioui Mohamed, Badis Abdelmalek   +5 more
doaj   +1 more source

The Application of Glycolipid-Type Microbial Biosurfactants as Active Pharmaceutical Ingredients for the Treatment and Prevention of Cancer [PDF]

Pharmaceuticals
Pharmaceutical scientists have researched the potential of secondary metabolites biosynthesized by microorganisms as active pharmaceutical ingredients (APIs) for the treatment of cancer.
Aileen M. B. McMahon, Matthew S. Twigg, Roger Marchant, Ibrahim M. Banat   +3 more
doaj   +2 more sources

Lipase-Catalyzed Production of Sorbitol Laurate in a “2-in-1” Deep Eutectic System: Factors Affecting the Synthesis and Scalability

Molecules, 2021
Surfactants, such as glycolipids, are specialty compounds that can be encountered daily in cleaning agents, pharmaceuticals or even in food. Due to their wide range of applications and, more notably, their presence in hygiene products, the demand is ...
André Delavault, Oleksandra Opochenska, Laura Laneque, Hannah Soergel, Claudia Muhle-Goll, Katrin Ochsenreither, Christoph Syldatk   +6 more
doaj   +1 more source

Cleaner synthesis of preclinically validated vaccine adjuvants

Frontiers in Chemistry, 2023
We developed synthetic glycophospholipids based on a glucosamine core (FP compounds) with potent and selective activity in stimulating Toll-Like Receptor 4 (TLR4) as agonists.
Alessio Romerio, Francesco Peri
doaj   +1 more source

Production and Characterization of New Biosurfactants/Bioemulsifiers from Pantoea alhagi and Their Antioxidant, Antimicrobial and Anti-Biofilm Potentiality Evaluations

Molecules, 2023
The present work aimed to develop rapid approach monitoring using a simple selective method based on a positive hemolysis test, oil spreading activity and emulsification index determinations.
Badiaa Essghaier, Nesrine Mallat, Khaoula Khwaldia, Filomena Mottola, Lucia Rocco, Hédia Hannachi   +5 more
doaj   +1 more source

The 20 years transition of clinical characteristics and metabolic risk factors in primary liver cancer patients from China

Frontiers in Oncology, 2023
BackgroundThe clinical characteristics of primary liver cancer (PLC) patients are changing, maybe due to hepatitis viral vaccination and lifestyle changes, etc.
Yezhou Ding, Mingyang Feng, Di Ma, Gangde Zhao, Xiaolin Wang, Baoyan An, Yumin Xu, Shike Lou, Lanyi Lin, Qing Xie, Kehui Liu, Shisan Bao, Hui Wang   +12 more
doaj   +1 more source

Microwave-Assisted One-Pot Lipid Extraction and Glycolipid Production from Oleaginous Yeast Saitozyma podzolica in Sugar Alcohol-Based Media

Molecules, 2021
Glycolipids are non-ionic surfactants occurring in numerous products of daily life. Due to their surface-activity, emulsifying properties, and foaming abilities, they can be applied in food, cosmetics, and pharmaceuticals.
André Delavault, Katarina Ochs, Olga Gorte, Christoph Syldatk, Erwann Durand, Katrin Ochsenreither   +5 more
doaj   +1 more source

Lipid A-Mediated Bacterial–Host Chemical Ecology: Synthetic Research of Bacterial Lipid As and Their Development as Adjuvants

Molecules, 2021
Gram-negative bacterial cell surface component lipopolysaccharide (LPS) and its active principle, lipid A, exhibit immunostimulatory effects and have the potential to act as adjuvants.
Atsushi Shimoyama, Koichi Fukase
doaj   +1 more source