Results 21 to 30 of about 50,959 (170)

A Glycolipid Adjuvant, 7DW8-5, Enhances the Protective Immune Response to the Current Split Influenza Vaccine in Mice

Frontiers in Microbiology, 2019
Vaccination is an effective strategy to control influenza disease. Adjuvants enhance the efficacy of vaccines, but few adjuvants are approved for human use, so novel, safe, and effective adjuvants are urgently needed.
Huapeng Feng, Noriko Nakajima, Li Wu, Makoto Yamashita, Tiago J. S. Lopes, Moriya Tsuji, Hideki Hasegawa, Tokiko Watanabe, Yoshihiro Kawaoka, Yoshihiro Kawaoka, Yoshihiro Kawaoka   +10 more
doaj   +1 more source

Structure Elucidation and Characterization of Novel Glycolipid Biosurfactant Produced by Rouxiella badensis DSM 100043^T

Molecules
Microbial biosurfactants have become increasingly attractive as promising ingredients for environmentally friendly products. The reasons for this are their generally good performance and biodegradability, low toxicity, production from renewable raw ...
Andre Fahriz Perdana Harahap, Jürgen Conrad, Mario Wolf, Jens Pfannstiel, Iris Klaiber, Jakob Grether, Eric Hiller, Maliheh Vahidinasab, Hanna Salminen, Chantal Treinen, Elvio Henrique Benatto Perino, Rudolf Hausmann   +11 more
doaj   +1 more source

Immunological hyporesponsiveness in tuberculosis: The role of mycobacterial glycolipids

Frontiers in Immunology, 2022
Glycolipids constitute a major part of the cell envelope of Mycobacterium tuberculosis (Mtb). They are potent immunomodulatory molecules recognized by several immune receptors like pattern recognition receptors such as TLR2, DC-SIGN and Dectin-2 on ...
Margarida Correia-Neves, Margarida Correia-Neves, Margarida Correia-Neves, Jérôme Nigou, Zaynab Mousavian, Zaynab Mousavian, Zaynab Mousavian, Christopher Sundling, Christopher Sundling, Christopher Sundling, Gunilla Källenius, Gunilla Källenius   +11 more
doaj   +1 more source

Determination of lipid-bound sulfate by ion chromatography and its application to quantification of sulfolipids from kidneys of various mammalian species

Journal of Lipid Research, 2001
A variety of procedures have been developed for determining the sulfate ester content of various biomolecules. Ion chromatography (IC), that is, quantitation of ionic substances by ion conductimetry after separation by anion-exchange chromatography, has ...
Keiko Tadano-Aritomi, Toshiyuki Hikita, Atsushi Suzuki, Hidenao Toyoda, Toshihiko Toida, Toshio Imanari, Ineo Ishizuka   +6 more
doaj   +1 more source

The History of Carbohydrates in Type I Allergy

Frontiers in Immunology, 2020
Although first described decades ago, the relevance of carbohydrate specific antibodies as mediators of type I allergy had not been recognized until recently.
Miriam Hils, Florian Wölbing, Christiane Hilger, Jörg Fischer, Nils Hoffard, Tilo Biedermann, Tilo Biedermann   +6 more
doaj   +1 more source

Stimulation of Natural Killer T Cells by Glycolipids

Molecules, 2013
Natural killer T (NKT) cells are a subset of T cells that recognize glycolipid antigens presented by the CD1d protein. The initial discovery of immunostimulatory glycolipids from a marine sponge and the T cells that respond to the compounds has led to ...
Brian L. Anderson, Luc Teyton, Albert Bendelac, Paul B. Savage   +3 more
doaj   +1 more source

Planococcus Species – An Imminent Resource to Explore Biosurfactant and Bioactive Metabolites for Industrial Applications

Frontiers in Bioengineering and Biotechnology, 2020
The marine environment represents a well-off and diverse group of microbes, which offers an enormous natural bioactive compounds of commercial importance.
Samadhan Waghmode, Mangesh Suryavanshi, Deepansh Sharma, Surekha K. Satpute   +3 more
doaj   +1 more source

Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms

Advanced Functional Materials, EarlyView.
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger, Min Jiang, Florian Belger, Fabian Link, Benjamin Winkeljann, Olivia M. Merkel   +5 more
wiley   +1 more source

CD1d-Restricted Type II NKT Cells Reactive With Endogenous Hydrophobic Peptides

Frontiers in Immunology, 2018
NKT cells belong to a distinct subset of T cells that recognize hydrophobic antigens presented by major histocompatibility complex class I-like molecules, such as CD1d.
Yusuke Nishioka, Sakiko Masuda, Utano Tomaru, Akihiro Ishizu   +3 more
doaj   +1 more source

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

Advanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang, Jiani Deng, Man Yee Cheung, Tingting Fu, Xufeng Qi, Dongqing Cai, Jianmin Sun, Gang Lu, Peng Shi, Wai‐Yee Chan, Xu Li, Hui Zhao   +11 more
wiley   +1 more source