Results 21 to 30 of about 48,007 (235)

Structure Elucidation and Characterization of Novel Glycolipid Biosurfactant Produced by Rouxiella badensis DSM 100043^T

Molecules
Microbial biosurfactants have become increasingly attractive as promising ingredients for environmentally friendly products. The reasons for this are their generally good performance and biodegradability, low toxicity, production from renewable raw ...
Andre Fahriz Perdana Harahap, Jürgen Conrad, Mario Wolf, Jens Pfannstiel, Iris Klaiber, Jakob Grether, Eric Hiller, Maliheh Vahidinasab, Hanna Salminen, Chantal Treinen, Elvio Henrique Benatto Perino, Rudolf Hausmann   +11 more
doaj   +1 more source

Immunological hyporesponsiveness in tuberculosis: The role of mycobacterial glycolipids

Frontiers in Immunology, 2022
Glycolipids constitute a major part of the cell envelope of Mycobacterium tuberculosis (Mtb). They are potent immunomodulatory molecules recognized by several immune receptors like pattern recognition receptors such as TLR2, DC-SIGN and Dectin-2 on ...
Margarida Correia-Neves, Margarida Correia-Neves, Margarida Correia-Neves, Jérôme Nigou, Zaynab Mousavian, Zaynab Mousavian, Zaynab Mousavian, Christopher Sundling, Christopher Sundling, Christopher Sundling, Gunilla Källenius, Gunilla Källenius   +11 more
doaj   +1 more source

Chemoenzymatic Synthesis of Well‐Defined α(2,8)‐ and α(2,9)‐Linked Oligosialosides

Angewandte Chemie, EarlyView.
Well‐defined α(2,8)‐ and α(2,9)‐linked oligosialic acids of different lengths can be prepared by employing recombinant bacterial polysialyltransferases in combination with chemically modified CMP‐Neu5Ac derivatives. After transfer, a sialoside is formed bearing an artificial entity, which blocks further glycosylation.
Jelle A. Fok, Keshav Kishor, Mehman I. Bunyatov, Gerlof P. Bosman, Geert‐Jan Boons   +4 more
wiley   +2 more sources

Determination of lipid-bound sulfate by ion chromatography and its application to quantification of sulfolipids from kidneys of various mammalian species

Journal of Lipid Research, 2001
A variety of procedures have been developed for determining the sulfate ester content of various biomolecules. Ion chromatography (IC), that is, quantitation of ionic substances by ion conductimetry after separation by anion-exchange chromatography, has ...
Keiko Tadano-Aritomi, Toshiyuki Hikita, Atsushi Suzuki, Hidenao Toyoda, Toshihiko Toida, Toshio Imanari, Ineo Ishizuka   +6 more
doaj   +1 more source

Unraveling A4GALT Mechanism and Its Modulation With Adamantyl‐Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies

Angewandte Chemie, EarlyView.
A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster, Òscar Vidal‐Gironès, Rowan de Graaf, Ken Kok, Lindsey T. Lelieveld, Jackelien Hoogervorst, Maria J. Ferraz, José Pablo Rivas‐Fernández, Rob F. Lammers, Herman S. Overkleeft, Johannes M. F. G. Aerts, Rolf G. Boot, Carme Rovira, Marta Artola   +13 more
wiley   +2 more sources

The History of Carbohydrates in Type I Allergy

Frontiers in Immunology, 2020
Although first described decades ago, the relevance of carbohydrate specific antibodies as mediators of type I allergy had not been recognized until recently.
Miriam Hils, Florian Wölbing, Christiane Hilger, Jörg Fischer, Nils Hoffard, Tilo Biedermann, Tilo Biedermann   +6 more
doaj   +1 more source

Stimulation of Natural Killer T Cells by Glycolipids

Molecules, 2013
Natural killer T (NKT) cells are a subset of T cells that recognize glycolipid antigens presented by the CD1d protein. The initial discovery of immunostimulatory glycolipids from a marine sponge and the T cells that respond to the compounds has led to ...
Brian L. Anderson, Luc Teyton, Albert Bendelac, Paul B. Savage   +3 more
doaj   +1 more source

Planococcus Species – An Imminent Resource to Explore Biosurfactant and Bioactive Metabolites for Industrial Applications

Frontiers in Bioengineering and Biotechnology, 2020
The marine environment represents a well-off and diverse group of microbes, which offers an enormous natural bioactive compounds of commercial importance.
Samadhan Waghmode, Mangesh Suryavanshi, Deepansh Sharma, Surekha K. Satpute   +3 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

CD1d-Restricted Type II NKT Cells Reactive With Endogenous Hydrophobic Peptides

Frontiers in Immunology, 2018
NKT cells belong to a distinct subset of T cells that recognize hydrophobic antigens presented by major histocompatibility complex class I-like molecules, such as CD1d.
Yusuke Nishioka, Sakiko Masuda, Utano Tomaru, Akihiro Ishizu   +3 more
doaj   +1 more source