Results 31 to 40 of about 50,959 (170)
Advanced Science, EarlyView.This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang +14 more
wiley +1 more source
Frontiers in Microbiology, 2015 Cryptococcosis caused by C. neoformans and C. gattii affects a large population and is a cause of significant morbidity and mortality. Despite its public health burden, there are currently no vaccines against cryptococcosis and new strategies against ...
Antonella eRella +9 more
doaj +1 more source
Advanced Science, EarlyView.Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke +10 more
wiley +1 more source
Altered expression of glycobiology-related genes in Parkinson’s disease brain
Frontiers in Molecular Neuroscience, 2022 The precise mechanisms initiating and perpetuating the cellular degeneration in Parkinson’s disease (PD) remain unclear. There is decreased expression of the main brain gangliosides, and GM1 ganglioside in particular, in the PD brain along with decreased
Jay S. Schneider, Garima Singh
doaj +1 more source
Advanced Science, EarlyView.Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng +14 more
wiley +1 more source
Advanced Science, EarlyView.Secreted glycoproteins report on cellular state faster than the cell surface, yet remain hard to measure. The Enzyme‐Linked Cycloaddition Assay (ELCA) combines metabolic azide labeling with click chemistry in an ELISA‐like microplate format, resolving sialylation changes within minutes for 1‐2 EUR per sample.
Jon Lundstrøm +2 more
wiley +1 more source
Journal of the American Oil Chemists' Society, EarlyView.ABSTRACT Microalgal oil is a sustainable source of omega‐3 polyunsaturated fatty acids. However, it is very sensitive to lipid oxidation, especially in emulsions. While the presence of phospholipids and galactolipids in microalgal oil can influence its oxidation, their impact in oil‐in‐water emulsion is not yet fully understood. This study investigates
Weiwei Sun +2 more
wiley +1 more source
Role of sulfatide in normal and pathological cells and tissues
Journal of Lipid Research, 2012 Sulfatide is 3-O-sulfogalactosylceramide that is synthesized by two transferases (ceramide galactosyltransferase and cerebroside sulfotransferase) from ceramide and is specifically degraded by a sulfatase (arylsulfatase A). Sulfatide is a multifunctional
Tadanobu Takahashi, Takashi Suzuki
doaj +1 more source
Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies
Animal Research and One Health, EarlyView.Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu +6 more
wiley +1 more source
OENO One, 1993 Les biostimulants apportés par voie foliaire ont un effet sur la composition lipidique des feuilles qui les reçoivent et des feuilles qui apparaissent ensuite.
Mohamed Bentchikou +2 more
doaj +1 more source