Results 41 to 50 of about 54,011 (265)

Role of Sterylglucosidase 1 (Sgl1) on the pathogenicity of Cryptococcus neoformans: potential applications for vaccine development

open access: yesFrontiers in Microbiology, 2015
Cryptococcosis caused by C. neoformans and C. gattii affects a large population and is a cause of significant morbidity and mortality. Despite its public health burden, there are currently no vaccines against cryptococcosis and new strategies against ...
Antonella eRella   +9 more
doaj   +1 more source

Synthesis and Anticancer Activity of Novel Deoxoartemisinin-Glycolipid Hybrids [PDF]

open access: yes, 2014
The practical synthesis and anticancer activity of novel deoxoartemisinin-glycolipid hybrids, which incorporate two drugs into a single molecule and can impact multiple targets simultaneously are presented.
박광균, 정원윤, 김기림
core   +1 more source

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

open access: yesAdvanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer   +5 more
wiley   +1 more source

Water-soluble trehalose glycolipids show superior Mincle binding and signaling but impaired phagocytosis and IL-1β production

open access: yesFrontiers in Molecular Biosciences, 2022
The tremendous potential of trehalose glycolipids as vaccine adjuvants has incentivized the study of how the structures of these ligands relate to their Mincle-mediated agonist activities.
M. A. Thathsaranie P. Manthrirathna   +15 more
doaj   +1 more source

Glycolipid‐peptide conjugate vaccines elicit CD8+ T‐cell responses and prevent breast cancer metastasis

open access: yesClinical & Translational Immunology, 2022
Objectives Metastasis is the principal cause of breast cancer mortality. Vaccines targeting breast cancer antigens have yet to demonstrate clinical efficacy, and there remains an unmet need for safe and effective treatment to reduce the risk of ...
Olivia K Burn   +15 more
doaj   +1 more source

The Biosurfactants Mannosylerythritol Lipids (MELs) as Stimulant on the Germination of Lactuca sativa L.

open access: yesAgriculture, 2023
The application of pesticides in agriculture leads to improved crop quality and promotes high productivity. However, the uninterrupted use of these chemicals is directly related to environmental impacts, affecting biodiversity and the health of ...
Renato Dias Matosinhos   +4 more
doaj   +1 more source

Glycolipid transfer proteins [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2007
Glycolipid transfer proteins (GLTPs) are small (24 kDa), soluble, ubiquitous proteins characterized by their ability to accelerate the intermembrane transfer of glycolipids in vitro. GLTP specificity encompasses both sphingoid- and glycerol-based glycolipids, but with a strict requirement that the initial sugar residue be beta-linked to the hydrophobic
Rhoderick E, Brown, Peter, Mattjus
openaire   +2 more sources

Thieme Chemistry Journal Awardees - Where are They Now? Synthesis of the Marine Glycolipid Dioctadecanoyl Discoside

open access: yes, 2009
The first synthesis of the inositol-containing marine glycolipid dioctadecanoyl discoside is reported. The key glycosylation reaction proceeds with ß-selectivity at reduced temperature.
Miller
core   +1 more source

Glycolipid self-assembly: micellar structure [PDF]

open access: yes, 1991
Small-angle scattering is used to investigate a typical glycolipid micelle structure in conjunction with NMR determination of sugar cycle conformation.
Perly, Bruno   +3 more
core   +1 more source

The role of transport proteins in the production of microbial glycolipid biosurfactants

open access: yes, 2021
Several microorganisms are currently being used as production platform for glycolipid biosurfactants, providing a greener alternative to chemical biosurfactants.
Jenkins Sánchez, Liam Richard   +2 more
core   +1 more source

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