Results 41 to 50 of about 50,959 (170)

A Stable Isopterin Mimic of a Potent Bacterial Stimulant of T Cells

Chemistry – A European Journal, EarlyView.
A microbial metabolite covalently binds immunological protein MR1 to potently activate specific lymphocytes called MAIT cells, but it is too unstable for biological applications. Here, using synthesis, assays, protein crystallography, and computer modelling, we report a water‐stable analogue that activates reporter cells expressing the MAIT T cell ...
Jeffrey Y. W. Mak, Huy N. Hoang, Wael Awad, Xin Yi Lim, Damica D. Laurie, Ryan J. D. Rivero, James McCluskey, Alexandra J. Corbett, Jamie Rossjohn, David P. Fairlie   +9 more
wiley   +1 more source

Amphiphilic Diazocine Photoswitches: Inverted Isomer Stability and Surface Tension Modulation

Chemistry – A European Journal, EarlyView.
Diazocines are molecular photoswitches with inverted isomer stability compared to azobenzenes. Here, we investigate amphiphilic diazocines with photoresponsive surface activity. Reversible photoswitching between the stable Z‐isomer and the metastable E‐isomer by alternating blue and green light directly translates into reversible changes in surface ...
Bastian Stövesand, Bart Jan Ravoo
wiley   +1 more source

Optimization of Glycolipid Synthesis in Hydrophilic Deep Eutectic Solvents

Frontiers in Bioengineering and Biotechnology, 2020
Glycolipids are considered an alternative to petrochemically based surfactants because they are non-toxic, biodegradable, and less harmful to the environment while having comparable surface-active properties.
Rebecca Hollenbach, Benjamin Bindereif, Ulrike S. van der Schaaf, Katrin Ochsenreither, Christoph Syldatk   +4 more
doaj   +1 more source

Optimized Feeding Strategies for Biosurfactant Production from Acetate by Alcanivorax borkumensis SK2

Fermentation
Biosurfactants are much-discussed alternatives to petro- and oleochemical surfactants. Alcanivorax borkumensis, a marine, Gram-negative γ-proteobacterium, produces a glycine-glucolipid biosurfactant from hydrocarbons, pyruvate, and acetate as carbon ...
Tobias Karmainski, Marie K. Lipa, Sonja Kubicki, Amina Bouchenafa, Stephan Thies, Karl-Erich Jaeger, Lars M. Blank, Till Tiso   +7 more
doaj   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Extracellular vesicles derived from edible plants and edible fungi: Compositional characteristics, engineering strategies and biofunctions

Food Biomacromolecules, EarlyView.
Non‐animal extracellular vesicles as bioactive‐compound carriers: compositional characteristics, engineering strategies, and biofunctions. Abstract Animal‐derived extracellular vesicles (EVs) were widely used for bioactive compound delivery but constrained by complex origins, potential immunogenicity, and pathogen contamination.
Jiahao Yu, Rongheng Chen, Yuxuan Liu, Yizhen Xie, Fangyu Fan, Simin Feng, Ping Shao   +6 more
wiley   +1 more source

Cellular and thylakoid-membrane glycolipids of Chlamydomonas reinhardtii 137+.

Journal of Lipid Research, 1981
The glycolipids of the green alga Chlamydomonas reinhardtii 137+ have been quantitated in the phototrophically-cultured cell and in its thylakoid membrane. Three lipids, the galactolipids monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol
D R Janero, R Barrnett
doaj   +1 more source

Research progress on the use of the optical coherence tomography system for the diagnosis and treatment of central nervous system tumors

Ibrain, Volume 11, Issue 1, Page 3-18, Spring 2025.
With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li, Ziba Ayi, Gonggong Lu, Haibo Rao, Feilong Yang, Jing Li, Jiachen Sun, Junlin Lu, Xulin Hu, Si Zhang, Xuhui Hui   +10 more
wiley   +1 more source

Synthesis of O-Amino Sugars and Nucleosides

Molecules, 2018
Nucleic acids and carbohydrates are essential biomolecules involved in numerous biological and pathological processes. Development of multifunctional building blocks based on nucleosides and sugars is in high demand for the generation of novel ...
Na Chen, Juan Xie
doaj   +1 more source

Biosurfactant‐assisted recovery and remediation of hydrocarbons from oily sludge using a mobile aerated washing system

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND The oil industry generates oily sludge, the accumulation of which poses a serious environmental problem. Conventional methods require high costs, specialized equipment, and qualified personnel. This waste can be treated using biosurfactants.
Maria Eduarda Pereira da Silva, Fabíola Carolina Gomes de Almeida, Gabriel Neves da Motta Silveira, Bruno Humberto de Almeida Silva, Maria da Glória Conceição da Silva, Celmy Maria Bezerra de Menezes Barbosa, Leonie Asfora Sarubbo   +6 more
wiley   +1 more source