Results 61 to 70 of about 46,712 (217)

α-Lactosylceramide Protects Against iNKT-Mediated Murine Airway Hyperreactivity and Liver Injury Through Competitive Inhibition of Cd1d Binding

open access: yesFrontiers in Chemistry, 2019
Invariant natural killer T (iNKT) cells, which are activated by T cell receptor (TCR)-dependent recognition of lipid-based antigens presented by the CD1d molecule, have been shown to participate in the pathogenesis of many diseases, including asthma and ...
Alan Chuan-Ying Lai   +7 more
doaj   +1 more source

Targeting Microbiome Metabolites: Reshaping Immunotherapy and Clinical Management Strategies for Colorectal Cancer

open access: yesiMetaMed, EarlyView.
The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang   +3 more
wiley   +1 more source

Diacetylene‐Functionalized Glycan Mimetics for Receptor‐Mediated Cluster Imprinting in Model Membranes

open access: yesMacromolecular Rapid Communications, EarlyView.
Diacetylene‐containing glycan mimetics cluster upon selective lectin binding in GUVs. Subsequent irradiation leads to the formation of fluorescent polymer clusters, while non‐clustered glycan mimetics remain unaffected in the membrane. ABSTRACT The glycocalyx, a dense layer of glycoproteins and glycolipids on eukaryotic cells, is essential for cellular
Luca‐Cesare Blawitzki   +5 more
wiley   +1 more source

Exploring a Novel Anti-Inflammatory Therapy for Diabetic Retinopathy Based on Glyco-Zeolitic-Imidazolate Frameworks

open access: yesPharmaceutics
Background/Objectives: Diabetic retinopathy is an ocular disease caused by changes in the expression of inflammatory mediators and increased oxidative stress in the retina and is the leading cause of vision loss in diabetic patients.
Elena Díaz-Paredes   +6 more
doaj   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi   +2 more
wiley   +1 more source

Tumor-infiltrating macrophages influence the glycosphingolipid composition of murine brain tumors

open access: yesJournal of Lipid Research, 1998
A procedure was developed to analyze glycosphingolipids (GSLs) in tumor-infiltrating macrophages (TIMs). The procedure entailed dissociating tumors into single cell suspensions with a concurrent metabolic labeling of GSLs using [14C]galactose.
Jeffrey A. Ecsedy   +3 more
doaj   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui   +4 more
wiley   +1 more source

glycolipids

open access: yes, 2014
Citation: 'glycolipids' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.G02653 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Heart failure in two male patients with late‐onset Fabry mutation (IVS4 + 919G > A)

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 1508-1513, April 2025.
Xufei Yang   +3 more
wiley   +1 more source

Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song   +3 more
wiley   +1 more source

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