Results 81 to 90 of about 50,959 (170)

Sulfated lactosyl archaeol (SLA) archaeosomes as a vaccine adjuvant

Human Vaccines & Immunotherapeutics
Archaeosomes are liposomes traditionally comprised of total polar lipids or semi-synthetic glycerolipids of ether-linked isoprenoid phytanyl cores with varied glycol- and amino-head groups. We have developed a semi-synthetic archaeosome formulation based
Bassel Akache, Michael J. McCluskie
doaj   +1 more source

Of mice and men—The emerging oral–gut–brain axis of health and disease

Periodontology 2000, EarlyView.
Abstract Objectives Oral health's inextricable links to systemic health are highlighted by the emerging oral–gut–brain axis and other well‐known axes. There is growing evidence of a complex oral–gut–brain axis linking mouth and gut microbiomes with the central nervous system.
Yvonne L. Hernandez‐Kapila, Daniel J. Weisenberger   +1 more
wiley   +1 more source

Editorial: Mycobacterial Glycolipids—Role in Immunomodulation and Targets for Vaccine Development

Frontiers in Immunology, 2020
Gunilla Källenius, Jérôme Nigou, Andrea Cooper, Margarida Correia-Neves, Margarida Correia-Neves, Margarida Correia-Neves   +5 more
doaj   +1 more source

A PIGG congenital disorder of glycosylation (PIGG‐CDG) variant associated with an Emm− red blood cell phenotype in a pediatric patient

Transfusion, EarlyView.
Abstract Background The high‐prevalence Emm antigen is an epitope on the GPI (glycosylphosphatidylinositol) glycolipid backbone, which anchors proteins to the cell surface. Inherited loss‐of‐function of PIGG (or PIGO) results in the rare Emm− red cell (RBC) phenotype and is associated with congenital disorders of glycosylation (CDG).
Alastair Murray, Connie M. Westhoff, Sunitha Vege, Hallie Lee‐Stroka, Randall W. Velliquette, William J. Lane, Jillian G. Buchan, Nabiha H. Saifee, Rida A. Hasan   +8 more
wiley   +1 more source

Beneath the Drought: Rhizosphere Processes Shape Genotype‐Specific Sorghum Responses to Drought‐Induced N Limitation

Plant, Cell &Environment, Volume 49, Issue 12, Page 9752-9769, December 2026.
ABSTRACT Droughts increasingly threaten crop productivity in nutrient‐depleted tropical soils. We investigated how water limitation influences rhizomicrobial traits (microbial biomass and functional community composition, enzyme activities) and nitrogen (N) uptake in three sorghum genotypes Makueni local (Mkl), Gadam (Gd), and IESH 22012 (IESH) under ...
Rosepiah Munene, Osman Mustafa, Sara Loftus, Vincent O. Suba, Nipuna Withanage, Niklas Schmücker, Peter Bulli, Reimund P. Rötter, Dennis O. Otieno, Mutez A. Ahmed, Michaela A. Dippold   +10 more
wiley   +1 more source

Glycolipids Derived from the Korean Endemic Plant Aruncus aethusifolius Inducing Glucose Uptake in Mouse Skeletal Muscle C2C12 Cells

Plants
Aruncus spp. has been used as a traditional folk medicine worldwide for its anti-inflammatory, hemostatic, and detoxifying properties. The well-known species A. dioicus var.
Jong Gwon Baek, Do Hwi Park, Ngoc Khanh Vu, Charuvaka Muvva, Hoseong Hwang, Sungmin Song, Hyeon-Seong Lee, Tack-Joong Kim, Hak Cheol Kwon, Keunwan Park, Ki Sung Kang, Jaeyoung Kwon   +11 more
doaj   +1 more source

Allergenicity of α‐Gal‐Containing Products

Allergy, EarlyView.
Frederik Bloch Mangaard, Esben Eller, Per Stahl Skov, Charlotte G. Mørtz, Carsten Bindslev‐Jensen   +4 more
wiley   +1 more source

Characterization of Lysosomal Hydrolases and Transporters and Their Age‐Dependent Variability: Relevance to Drug Metabolism and Transport of Small Molecule and Biologic Drugs

Clinical Pharmacology &Therapeutics, Volume 120, Issue 5, Page 1338-1347, November 2026.
Lysosomes play a key role in the accumulation, catabolism, and transport of endogenous and exogenous metabolites and proteins and are involved in drug metabolism and prodrug activation. However, the protein abundance and interindividual variability of lysosomal drug‐metabolizing enzymes and transporters (DMETs) remain underexplored.
Darshak Gadara, Dilip Kumar Singh, Sandhya Subash, Guihua Yue, Deepak Ahire, Chris Bohl, Maciej Czerwinski, Stephanie Helmstetter, Scott Heyward, Robert S. Jones, Cyrus Khojasteh, Ryota Kikuchi, Priyanka Kulkarni, Bin Ma, Bernard Murray, Chris Seib, Bill Smith, David M. Stresser, Mitchell E. Taub, Ting Wang, Bhagwat Prasad   +20 more
wiley   +1 more source

Chemical Synthesis of 6-Azido-6-Deoxy Derivatives of Phosphatidylinositol Containing Different Fatty Acid Chains

Molecules
This paper describes the synthesis of two 6-azido-6-deoxy derivatives of phosphatidylinositol (PI), which contained different fatty acid chains. These syntheses, starting from methyl α-d-glucopyranoside, employed multiple regioselective transformations ...
Mosidur Rahaman Molla, Palak Gupta, Rajendra Rohokale, Zhongwu Guo   +3 more
doaj   +1 more source

Aflatoxin B1 Exacerbates Ketogenic Diet‐Induced Hepatic Oxidative Stress and Glucose and Lipid Metabolic Disturbances in Mice

Food Frontiers, Volume 7, Issue 6, November 2026.
AFB1 exposure aggravates KD‐associated hepatic oxidative stress, inflammation, and glucose and lipid metabolic disturbances in mice. These effects are accompanied by dysregulation of AMPK, mTOR, and PPAR‐γ signaling and extensive hepatic metabolic reprogramming. ABSTRACT Aflatoxin B1 (AFB1) is a widespread mycotoxin with severe hepatotoxicity.
Xueyuan Hu, Zhenjun Sun, Xiaojing Wang, Shaochun Liu, ZhenBang Ye, Xueshu Han, Yang Ni, Linlin Hou, Yongping Chen, Huanqi Liu   +9 more
wiley   +1 more source