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Enhancing Student Comprehension of Glucose Metabolism Visualization Through Virtual Simulation Platform: An Educational Approach [PDF]

open access: yesPharmacology Research & Perspectives
With the rapid progression of biotechnology, the significance translational research on glycolysis in molecular pharmacology has become increasingly evident.
Luna Ge   +8 more
doaj   +2 more sources

Model evaluation for glycolytic oscillations in yeast biotransformations of xenobiotics [PDF]

open access: yesBiophysical Chemistry 109, 413-426 (2004), 2004
Anaerobic glycolysis in yeast perturbed by the reduction of xenobiotic ketones is studied numerically in two models which possess the same topology but different levels of complexity. By comparing both models' predictions for concentrations and fluxes as well as steady or oscillatory temporal behavior we answer the question what phenomena require what ...
Beaudoin   +48 more
arxiv   +5 more sources

The roles of glycolysis in osteosarcoma

open access: yesFrontiers in Pharmacology, 2022
Metabolic reprogramming is of great significance in the progression of various cancers and is critical for cancer progression, diagnosis, and treatment.
Zuxi Feng, Yanghuan Ou, Liang Hao
doaj   +3 more sources

Aerobic Inhibition of Glycolysis [PDF]

open access: bronzeNature, 1958
DURING investigations on the synthesis of sucrose from glucose-1-phosphate and fructose by pea seed extracts it was observed that a glycolytic system was operating in the enzymic digests1,2. The pea extract had been partially purified by precipitation with ammonium sulphate (80 per cent saturation) and dialysis against phosphate buffer at pH. 7.0.
John F. Turner, L. W. Mapson
openalex   +4 more sources

Isoscopoletin inhibits hepatocellular carcinoma cell proliferation via regulating glycolysis-related proteins. [PDF]

open access: yesPLoS ONE
ObjectiveIsoscopoletin is one of the primary metabolites of natural product scoparone, which was reported to against tumor proliferation. The aim of this study was to explore the mechanism of isoscopoletin against hepatocellular carcinoma (HCC ...
Chenyao Ruan   +3 more
doaj   +2 more sources

Role of glycolysis in retinal vascular endothelium, glia, pigment epithelium, and photoreceptor cells and as therapeutic targets for related retinal diseases [PDF]

open access: yesInternational Journal of Ophthalmology, 2021
Glycolysis produces large amounts of adenosine triphosphate (ATP) in a short time. The retinal vascular endothelium feeds itself primarily through aerobic glycolysis with less ATP.
Ting-Ting Yang, Hui Li, Li-Jie Dong
doaj   +1 more source

A prediction model identifying glycolysis signature as therapeutic target for psoriasis

open access: yesFrontiers in Immunology, 2023
BackgroundThe hyperproliferation featured with upregulated glycolysis is a hallmark of psoriasis. However, molecular difference of keratinocyte glycolysis amongst varied pathologic states in psoriasis remain elusive.ObjectivesTo characterize glycolysis ...
Yanhong Shou   +3 more
doaj   +1 more source

The significance of glycolysis index and its correlations with immune infiltrates in Alzheimer’s disease

open access: yesFrontiers in Immunology, 2022
Alzheimer’s disease (AD) is a common neurodegenerative disorder without an effective treatment, and results in an increasingly serious health problem. However, its pathogenesis is complex and poorly understood.
Zhiqiang Qiu   +8 more
doaj   +1 more source

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