Results 21 to 30 of about 339,187 (240)

Integrated analysis reveals critical glycolytic regulators in hepatocellular carcinoma

Cell Communication and Signaling, 2020
Background Cancer cells primarily utilize aerobic glycolysis for energy production, a phenomenon known as the Warburg effect. Increased aerobic glycolysis supports cancer cell survival and rapid proliferation and predicts a poor prognosis in cancer ...
Chenying Lu, Shiji Fang, Qiaoyou Weng, Xiuling Lv, Miaomiao Meng, Jinyu Zhu, Liyun Zheng, Yumin Hu, Yang Gao, Xulu Wu, Jianting Mao, Bufu Tang, Zhongwei Zhao, Li Huang, Jiansong Ji   +14 more
doaj   +1 more source

Hexokinases II‐mediated glycolysis governs susceptibility to crizotinib in ALK‐positive non‐small cell lung cancer

Thoracic Cancer, 2021
Background Activation of ALK leads to a high level of aerobic glycolysis related to crizotinib insensitivity in anaplastic lymphoma kinase‐positive non‐small cell lung cancer (ALK+ NSCLC).
Caiyu Lin, Hengyi Chen, Rui Han, Li Li, Conghua Lu, Shuai Hao, Yubo Wang, Yong He   +7 more
doaj   +1 more source

Data_Sheet_5_Identification of a Three-Glycolysis-Related lncRNA Signature Correlated With Prognosis and Metastasis in Clear Cell Renal Cell Carcinoma.xlsx

, 2022
The clear cell renal cell carcinoma (ccRCC) is not only a malignant disease but also an energy metabolic disease, we aimed to identify a novel prognostic model based on glycolysis-related long non-coding RNA (lncRNAs) and explore its mechanisms. With the
Tinghao Li (10507577), Junlong Zhu (10507568), Weiyang He (8079503), Hang Tong (10507565), Zijia Qin (10507574), Xudong Liu (6899), Siwen Yin (11659675), Yan Sun (22436)   +7 more
core   +1 more source

Image_1_Identification of a Three-Glycolysis-Related lncRNA Signature Correlated With Prognosis and Metastasis in Clear Cell Renal Cell Carcinoma.JPEG

, 2022
The clear cell renal cell carcinoma (ccRCC) is not only a malignant disease but also an energy metabolic disease, we aimed to identify a novel prognostic model based on glycolysis-related long non-coding RNA (lncRNAs) and explore its mechanisms. With the
Tinghao Li (10507577), Junlong Zhu (10507568), Weiyang He (8079503), Hang Tong (10507565), Zijia Qin (10507574), Xudong Liu (6899), Siwen Yin (11659675), Yan Sun (22436)   +7 more
core   +1 more source

Data_Sheet_3_Identification of a Three-Glycolysis-Related lncRNA Signature Correlated With Prognosis and Metastasis in Clear Cell Renal Cell Carcinoma.xlsx

, 2022
The clear cell renal cell carcinoma (ccRCC) is not only a malignant disease but also an energy metabolic disease, we aimed to identify a novel prognostic model based on glycolysis-related long non-coding RNA (lncRNAs) and explore its mechanisms. With the
Tinghao Li (10507577), Junlong Zhu (10507568), Weiyang He (8079503), Hang Tong (10507565), Zijia Qin (10507574), Xudong Liu (6899), Siwen Yin (11659675), Yan Sun (22436)   +7 more
core   +1 more source

SIPA1 Enhances Aerobic Glycolysis Through HIF-2α Pathway to Promote Breast Cancer Metastasis

Frontiers in Cell and Developmental Biology, 2022
Increased dependence on aerobic glycolysis is characteristic of most cancer cells, whereas the mechanism underlying the promotion of aerobic glycolysis in metastatic breast cancer cells under ambient oxygen has not been well understood.
Chenguang Yao, Jun Weng, Lingyun Feng, Wanjun Zhang, Yan Xu, Peijing Zhang, Yoshimasa Tanaka, Li Su   +7 more
doaj   +1 more source

Data_Sheet_4_Identification of a Three-Glycolysis-Related lncRNA Signature Correlated With Prognosis and Metastasis in Clear Cell Renal Cell Carcinoma.xlsx

, 2022
The clear cell renal cell carcinoma (ccRCC) is not only a malignant disease but also an energy metabolic disease, we aimed to identify a novel prognostic model based on glycolysis-related long non-coding RNA (lncRNAs) and explore its mechanisms. With the
Tinghao Li (10507577), Junlong Zhu (10507568), Weiyang He (8079503), Hang Tong (10507565), Zijia Qin (10507574), Xudong Liu (6899), Siwen Yin (11659675), Yan Sun (22436)   +7 more
core   +1 more source

Intratumor microbiome derived glycolysis-lactate signatures depicts immune heterogeneity in lung adenocarcinoma by integration of microbiomic, transcriptomic, proteomic and single-cell data

Frontiers in Microbiology, 2023
IntroductionMicrobiome plays roles in lung adenocarcinoma (LUAD) development and anti-tumor treatment efficacy. Aberrant glycolysis in tumor might promote lactate production that alter tumor microenvironment, affecting microbiome, cancer cells and immune
Xiaheng Deng, Xiru Chen, Yu Luo, Jun Que, Liang Chen   +4 more
doaj   +1 more source

PFKFB2-mediated glycolysis promotes lactate-driven continual efferocytosis by macrophages

Nature Metabolism, 2023
Resolving-type macrophages prevent chronic inflammation by clearing apoptotic cells through efferocytosis. These macrophages are thought to rely mainly on oxidative phosphorylation, but emerging evidence suggests a possible link between efferocytosis and
M. Schilperoort, D. Ngai, M. Katerelos, D. Power, I. Tabas   +4 more
semanticscholar   +1 more source

Data_Sheet_2_Identification of a Three-Glycolysis-Related lncRNA Signature Correlated With Prognosis and Metastasis in Clear Cell Renal Cell Carcinoma.xlsx

, 2022
The clear cell renal cell carcinoma (ccRCC) is not only a malignant disease but also an energy metabolic disease, we aimed to identify a novel prognostic model based on glycolysis-related long non-coding RNA (lncRNAs) and explore its mechanisms. With the
Tinghao Li (10507577), Junlong Zhu (10507568), Weiyang He (8079503), Hang Tong (10507565), Zijia Qin (10507574), Xudong Liu (6899), Siwen Yin (11659675), Yan Sun (22436)   +7 more
core   +1 more source