Results 81 to 90 of about 11,104 (213)
Systematic data integration platform for functional glycomics
Click on the DIO link to access this article (may not be free)Glycomics is a discipline of biology that deals with the structure and function of glycans (or carbohydrates).
George R. Bousfield +9 more
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Glycomics for Microbes and Microbiologists [PDF]
ABSTRACT The recent article “Lectin-Glycan Interaction Network-Based Identification of Host Receptors of Microbial Pathogenic Adhesins” by Ielasi et al. describes a new development in microbial carbohydrate analysis [Ielasi FS, Alioscha-Perez M, Donohue D, Claes S, Sahli H, Schols D, Willaert RG, mBio 7(4):e00584-16, 2016,
openaire +3 more sources
Phasevarions in Haemophilus influenzae biogroup aegyptius control expression of multiple proteins
Haemophilus influenzae biogroup aegyptius is the causative agent of Brazilian purpuric fever (BPF), an invasive disease with high mortality, that sporadically manifests in children previously suffering conjunctivitis. Though strains of H.
Greg Tram +7 more
doaj +1 more source
Galectin‐4: A Novel Mediator of Human Intervertebral Disc Degeneration
Galectin‐4 correlates with intervertebral disc degeneration, independent of age, sex, or underlying pathology. Functionally, it activates NF‐κB signaling and induces pro‐inflammatory and matrix‐degrading responses, with stronger effects in nucleus pulposus cells, identifying it as a novel molecular player in disc degeneration.
Christine Strauss +12 more
wiley +1 more source
'This handbook provides the first comprehensive overview of the emerging field of glycomics, defined as the study of all complex carbohydrates in an organism or cell ("the glycome").
Cummings, Richard D. +1 more
core
Design and Synthesis of a Potent, Cell Active Purine‐Based Amidoxime Against the Dengue Virus
Scaffold hopping from our previous indolazepinone hit exemplifies purine SP‐835G with DENV2 EC50 0.1 µM, CC50>100 µM, clogP 3.61. Docking studies support its amidine metabolite operates as an allosteric inhibitor of DENV(pro). A flexible ether linker appears pivotal for enhancing binding and activity.
Dimitrios Kiousis +8 more
wiley +1 more source
Biofilm extracellular polymeric substances (EPS) in Stenotrophomonas bentonitica BII‐R7 direct the formation of crystalline trigonal selenium nanorods. Comparative genomics identifies a unique genetic toolkit underpinning EPS composition and metal resilience, positioning this strain as a platform for bioremediation and green nanomaterial synthesis ...
Eduardo Perez‐Muelas +6 more
wiley +1 more source
Glycomics Hits the Big Time [PDF]
Cells run on carbohydrates. Glycans, sequences of carbohydrates conjugated to proteins and lipids, are arguably the most abundant and structurally diverse class of molecules in nature.
Hart, Gerald W. +3 more
core +1 more source
Quantitative Glycomics Strategies
The correlations between protein glycosylation and many biological processes and diseases are increasing the demand for quantitative glycomics strategies enabling sensitive monitoring of changes in the abundance and structure of glycans. This is currently attained through multiple strategies employing several analytical techniques such as capillary ...
Yehia, Mechref +4 more
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Fucanomics and Galactanomics: Marine Distribution, Medicinal Impact, Conceptions, and Challenges
Glycomics turned out to be a very extensive project where its subdivision is consequently emerging. This is seen by the growing number of terminologies used to define subprojects concerning particular classes of bioactive carbohydrates.
Vitor H. Pomin
doaj +1 more source

