Results 61 to 70 of about 8,797 (182)
Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley +1 more source
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui +4 more
wiley +1 more source
Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song +3 more
wiley +1 more source
Quantitative Glycomics Strategies
The correlations between protein glycosylation and many biological processes and diseases are increasing the demand for quantitative glycomics strategies enabling sensitive monitoring of changes in the abundance and structure of glycans. This is currently attained through multiple strategies employing several analytical techniques such as capillary ...
Yehia, Mechref +4 more
openaire +2 more sources
ABSTRACT Mesenchymal stem cells (MSCs) are adult stem cells able to self‐renewal or differentiation into different cell types, including chondrocytes. N‐Glycans are post‐translational modifications of glycoproteins that contribute to vital cell functions.
Houda Montacir +4 more
wiley +1 more source
Fucanomics and Galactanomics: Marine Distribution, Medicinal Impact, Conceptions, and Challenges
Glycomics turned out to be a very extensive project where its subdivision is consequently emerging. This is seen by the growing number of terminologies used to define subprojects concerning particular classes of bioactive carbohydrates.
Vitor H. Pomin
doaj +1 more source
ABSTRACT Bone defect repair in elderly patients is frequently compromised by reduced osteogenic capacity and delayed healing. Chronic inflammation‐driven inflammaging is a critical contributor to this impairment, characterized by dysfunctional autophagy in senescent macrophages (S‐MΦs), excessive reactive oxygen species (ROS) accumulation, and ...
Ruiyue Hang +6 more
wiley +1 more source
Some virulent strains of Campylobacter jejuni possess a putative chemotaxis receptor, Tlp11, of unknown function. Here the authors show that Tlp11 specifically interacts with galactose and is required for the chemotaxis response of C. jejunito galactose.
Christopher J. Day +9 more
doaj +1 more source
Advancing clinical precision medicine via peripheral blood immune single‐cell omics
Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Liyang Li +5 more
wiley +1 more source
Cryogenic Infrared Spectroscopy Unmasks Gas‐Phase Charge Migration in Mucin‐Type O‐Glycans
Protons in a sugar rush: O‐glycans are vital biomolecules, challenging to analyze due to isomeric forms. Using ion mobility spectrometry, cryogenic IR spectroscopy, and ab initio calculations, isomeric O‐glycan cores can be distinguished. At cryogenic temperatures, multiple deprotomers were identified, which interconvert at ambient conditions via rapid
Marc Safferthal +9 more
wiley +1 more source

