Results 61 to 70 of about 8,797 (182)

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

open access: yesMass Spectrometry Reviews, Volume 45, Issue 4, Page 599-623, July/August 2026.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

open access: yesMass Spectrometry Reviews, Volume 45, Issue 4, Page 800-828, July/August 2026.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui   +4 more
wiley   +1 more source

Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science

open access: yesMass Spectrometry Reviews, Volume 45, Issue 4, Page 829-850, July/August 2026.
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song   +3 more
wiley   +1 more source

Quantitative Glycomics Strategies

open access: yesMolecular & Cellular Proteomics, 2013
The correlations between protein glycosylation and many biological processes and diseases are increasing the demand for quantitative glycomics strategies enabling sensitive monitoring of changes in the abundance and structure of glycans. This is currently attained through multiple strategies employing several analytical techniques such as capillary ...
Yehia, Mechref   +4 more
openaire   +2 more sources

The N‐Glycome to Differentiate Mesenchymal Stem Cells Upon Chondrogenic Differentiation, Dedifferentiation, and Senescence

open access: yesPROTEOMICS, Volume 26, Issue 7, Page 17-27, July 2026.
ABSTRACT Mesenchymal stem cells (MSCs) are adult stem cells able to self‐renewal or differentiation into different cell types, including chondrocytes. N‐Glycans are post‐translational modifications of glycoproteins that contribute to vital cell functions.
Houda Montacir   +4 more
wiley   +1 more source

Fucanomics and Galactanomics: Marine Distribution, Medicinal Impact, Conceptions, and Challenges

open access: yesMarine Drugs, 2012
Glycomics turned out to be a very extensive project where its subdivision is consequently emerging. This is seen by the growing number of terminologies used to define subprojects concerning particular classes of bioactive carbohydrates.
Vitor H. Pomin
doaj   +1 more source

Targeting Inflammaging: A Metformin‐Releasing Titanium Implant Reprograms Senescent Macrophages to Orchestrate Angiogenesis and Osteogenesis

open access: yesRare Metals, Volume 45, Issue 7, July 2026.
ABSTRACT Bone defect repair in elderly patients is frequently compromised by reduced osteogenic capacity and delayed healing. Chronic inflammation‐driven inflammaging is a critical contributor to this impairment, characterized by dysfunctional autophagy in senescent macrophages (S‐MΦs), excessive reactive oxygen species (ROS) accumulation, and ...
Ruiyue Hang   +6 more
wiley   +1 more source

A direct-sensing galactose chemoreceptor recently evolved in invasive strains of Campylobacter jejuni

open access: yesNature Communications, 2016
Some virulent strains of Campylobacter jejuni possess a putative chemotaxis receptor, Tlp11, of unknown function. Here the authors show that Tlp11 specifically interacts with galactose and is required for the chemotaxis response of C. jejunito galactose.
Christopher J. Day   +9 more
doaj   +1 more source

Advancing clinical precision medicine via peripheral blood immune single‐cell omics

open access: yes
Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Liyang Li   +5 more
wiley   +1 more source

Cryogenic Infrared Spectroscopy Unmasks Gas‐Phase Charge Migration in Mucin‐Type O‐Glycans

open access: yesSmall, Volume 22, Issue 38, 8 July 2026.
Protons in a sugar rush: O‐glycans are vital biomolecules, challenging to analyze due to isomeric forms. Using ion mobility spectrometry, cryogenic IR spectroscopy, and ab initio calculations, isomeric O‐glycan cores can be distinguished. At cryogenic temperatures, multiple deprotomers were identified, which interconvert at ambient conditions via rapid
Marc Safferthal   +9 more
wiley   +1 more source

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