Results 71 to 80 of about 8,738 (176)

A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application

Advanced Science, Volume 13, Issue 29, 22 May 2026.
This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu, Weize Xu, Da Lin, Leqiang Sun, Jinxia Dai, Gang Cao   +5 more
wiley   +1 more source

Chondrocytes Contribute to Alphaviral Disease Pathogenesis as a Source of Virus Replication and Soluble Factor Production

Viruses, 2018
Arthritogenic alphavirus infections often result in debilitating musculoskeletal disorders that affect the joints, muscle, and bone. In order to evaluate the infection profile of primary human skeletal muscle and chondrocyte cells to Ross River virus ...
Elisa X. Y. Lim, Aroon Supramaniam, Hayman Lui, Peta Coles, Wai Suet Lee, Xiang Liu, Penny A. Rudd, Lara J. Herrero   +7 more
doaj   +1 more source

Integrated Glycome Strategy for Characterization of Aberrant LacNAc Contained N-Glycans Associated With Gastric Carcinoma

Frontiers in Oncology, 2019
Aberrant glycosylation is not only a feature of malignant cell transformation, but also plays an important role in metastasis. In the present study, an integrated strategy combining the lectin microarrays and lectin cytochemistry was employed to ...
Hanjie Yu, Xiaojie Li, Mengting Chen, Fan Zhang, Xiawei Liu, Jingmin Yu, Yaogang Zhong, Jian Shu, Wentian Chen, Haoqi Du, Kun Zhang, Chen Zhang, Jing Zhang, Hailong Xie, Zheng Li   +14 more
doaj   +1 more source

Bacillus spp. in Fish Farming: Enhancing Fish Performance, Health and Farming Practices

Aquaculture Nutrition
Aquaculture has become a crucial component of global food and nutrition security, offering a sustainable alternative to meet the growing demand for seafood while alleviating pressure on wild fish populations.
Yaoying Lu, Natasha B. Bambridge, Xiaojing Chen, Yunjiang Feng   +3 more
doaj   +1 more source

Heparanase inhibition prevents glycocalyx damage and albuminuria in experimental minimal change disease

Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
Michael Crompton, Raina D. Ramnath, Kai Betteridge, Sara Desideri, Aldara Martin Alonso, Lulu Jiang, Monica Gamez, Holly Stowell‐Connolly, Viktoriia Vasylchenko, Karen L. Onions, Matthew J. Butler, Chris R. Neal, Andrew H. J. Salmon, Jeremy E. Turnbull, Hiroshi Kawachi, Olga V. Zubkova, Gavin I. Welsh, Simon C. Satchell, Rebecca R. Foster   +18 more
wiley   +1 more source

Targeting Human Parainfluenza Virus Type-1 Haemagglutinin-Neuraminidase with Mechanism-Based Inhibitors

Viruses, 2019
Human parainfluenza virus (hPIV) infections are a major cause of respiratory tract illnesses in children, with currently no available vaccine or drug treatment.
Tanguy Eveno, Larissa Dirr, Ibrahim M. El-Deeb, Patrice Guillon, Mark von Itzstein   +4 more
doaj   +1 more source

An LNP antiviral siRNA drug cocktail delivered intranasally is effective against a range of respiratory viruses

Virology Journal
SARS-CoV-2, influenza A virus (IAV), and respiratory syncytial virus (RSV) are leading causes of acute respiratory infections globally, often presenting with overlapping clinical features that complicate timely diagnosis and treatment.
Victor Baba Oti, Tufael Ahmed, Wenqing Gao, Dhruba Acharya, Lucy Wales-Earl, Allan Hicks, Nigel AJ McMillan, Adi Idris   +7 more
doaj   +1 more source

Disruption of IL-17-mediated immunosurveillance in the respiratory mucosa results in invasive Streptococcus pyogenes infection

Frontiers in Immunology
IntroductionStreptococcus pyogenes is a Gram-positive pathogen that causes a significant global burden of skin pyoderma and pharyngitis. In some cases, infection can lead to severe invasive streptococcal diseases.
Jamie-Lee Mills, Ailin Lepletier, Victoria Ozberk, Jessica Dooley, Jacqualine Kaden, Ainslie Calcutt, Yongbao Huo, Allan Hicks, Ali Zaid, Michael F. Good, Manisha Pandey   +10 more
doaj   +1 more source

Grappling with the glycome

International Journal of Experimental Pathology, 2004
The spring 2004 meeting of the BSMB was held at Hulme Hall, University of Manchester on 5–6 April. The theme of the meeting was recent advances in our understanding of the structure and biological function of saccharides, with a particular emphasis on glycosaminoglycans.
Gavin C. Jones, Nicholas T. Seyfried, Edward R. Bastow   +2 more
openaire   +2 more sources

Glycosylation of extracellular vesicles: current knowledge, tools and clinical perspectives

Journal of Extracellular Vesicles, 2018
It is now acknowledged that extracellular vesicles (EVs) are important effectors in a vast number of biological processes through intercellular transfer of biomolecules.
Charles Williams, Felix Royo, Oier Aizpurua-Olaizola, Raquel Pazos, Geert-Jan Boons, Niels-Christian Reichardt, Juan M. Falcon-Perez   +6 more
doaj   +1 more source