Results 51 to 60 of about 15,452 (231)

Role of ammonia for brain abnormal protein glycosylation during the development of hepatitis B virus-related liver diseases

open access: yesCell & Bioscience, 2022
Background Ammonia is the most typical neurotoxin in hepatic encephalopathy (HE), but the underlying pathophysiology between ammonia and aberrant glycosylation in HE remains unknown.
Jiajun Yang   +12 more
doaj   +1 more source

A golden age for working with public proteomics data [PDF]

open access: yes, 2017
Data sharing in mass spectrometry (MS)-based proteomics is becoming a common scientific practice, as is now common in the case of other, more mature 'omics' disciplines like genomics and transcriptomics.
Martens, Lennart   +1 more
core   +1 more source

Quantitative Glycomics Strategies

open access: yesMolecular & Cellular Proteomics, 2013
The correlations between protein glycosylation and many biological processes and diseases are increasing the demand for quantitative glycomics strategies enabling sensitive monitoring of changes in the abundance and structure of glycans. This is currently attained through multiple strategies employing several analytical techniques such as capillary ...
Yehia, Mechref   +4 more
openaire   +2 more sources

Diverse Sensory Repertoire of Paralogous Chemoreceptors Tlp2, Tlp3, and Tlp4 in Campylobacter jejuni

open access: yesMicrobiology Spectrum, 2022
Campylobacter jejuni responds to extracellular stimuli via transducer-like chemoreceptors (Tlps). Here, we describe receptor-ligand interactions of a unique paralogue family of dCache_1 (double Calcium channels and chemotaxis) chemoreceptors: Tlp2, Tlp3,
Taha   +9 more
doaj   +1 more source

Contribution of cryptic epitopes in designing a group A streptococcal vaccine

open access: yesHuman Vaccines & Immunotherapeutics, 2018
A successful vaccine needs to target multiple strains of an organism. Streptococcus pyogenes is an organism that utilizes antigenic strain variation as a successful defence mechanism to circumvent the host immune response. Despite numerous efforts, there
Victoria Ozberk   +2 more
doaj   +1 more source

The potential of glycomics as prognostic biomarkers in liver disease and liver transplantation [PDF]

open access: yes, 2019
The study of glycomics is a novel and fascinating approach for the development of biomarkers. It has become clear that in the field of liver disease specific glycomic patters are present in specific disease states, which has led to the development of ...
Callewaert, Nico   +3 more
core  

Chemoenzymatic Probes for Detecting and Imaging Fucose-α(1-2)-galactose Glycan Biomarkers [PDF]

open access: yes, 2012
The disaccharide motif fucose-α(1-2)-galactose (Fucα(1-2)Gal) is involved in many important physiological processes, such as learning and memory, inflammation, asthma, and tumorigenesis.
Becker D. J.   +30 more
core   +3 more sources

A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application

open access: yesAdvanced Science, EarlyView.
This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu   +5 more
wiley   +1 more source

Structural and functional glycosphingolipidomics by glycoblotting with aminooxy-functionalized gold nanoparticle [PDF]

open access: yes, 2008
Glycosphingolipids (GSLs) synthesized in Golgi apparatus by sequential transfer of sugar residues to a ceramide lipid anchor are ubiquitously distributing on vertebrate plasma membranes.
Midori Abe   +2 more
core   +1 more source

Lipidomics in Health and Diseases - Beyond the Analysis of Lipids [PDF]

open access: yes, 2014
published_or_final_versio
Fan, P, Li, M, Wang, Y
core   +1 more source

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