Results 31 to 40 of about 11,104 (213)

Bioinformatics Approach for Functional Glycomics [PDF]

, 2007
Presentation in the Human Glycomics Proteomics Disease Initiative (HGPI ...
James C. Paulson
core   +1 more source

Introducing glycomics data into the Semantic Web [PDF]

, 2013
Background: Glycoscience is a research field focusing on complex carbohydrates (otherwise known as glycans)a, which can, for example, serve as “switches” that toggle between different functions of a glycoprotein or glycolipid.
Jin-Dong Kim, Masaaki Matsubara, Thomas Lütteke, Lutteke, Thomas, Narimatsu, Hisashi, Kim, Jin-Dong, Aoki-Kinoshita, Kiyoko F., Toshihide Shikanai, Yoshinori Suzuki, Suzuki, Yoshinori, Matthew P Campbell, Shikanai, Toshihide, Shujiro Okuda, Ranzinger, Rene, Kawano, Shin, Jerven Bolleman, Philip Toukach, Sawaki, Hiromichi, Kiyoko F Aoki-Kinoshita, Toukach, Philip, Hiromichi Sawaki, Matsubara, Masaaki, Campbell, Matthew P., Shin Kawano, Okuda, Shijiro, Packer, Nicolle H., Bolleman, Jerven, Rene Ranzinger, Shinmachi, Daisuke, Daisuke Shinmachi, Issaku Yamada, Hisashi Narimatsu, Yamada, Iaaku, Nicolle H Packer   +33 more
core   +1 more source

Consortium for Functional Glycomics Overview [PDF]

, 2007
This presentation provides an overview of the Consortium for Functional ...
James C. Paulson
core   +1 more source

Multidisciplinary Approaches Identify Compounds that Bind to Human ACE2 or SARS-CoV-2 Spike Protein as Candidates to Block SARS-CoV-2–ACE2 Receptor Interactions

mBio, 2021
SARS-CoV-2, the causative agent of COVID-19, has caused more than 60 million cases worldwide with almost 1.5 million deaths as of November 2020. Repurposing existing drugs is the most rapid path to clinical intervention for emerging diseases.
Christopher J. Day, Benjamin Bailly, Patrice Guillon, Larissa Dirr, Freda E.-C. Jen, Belinda L. Spillings, Johnson Mak, Mark von Itzstein, Thomas Haselhorst, Michael P. Jennings   +9 more
doaj   +1 more source

Bovine Milk Glycome [PDF]

Journal of Dairy Science, 2008
Bovine milk oligosaccharides have several potentially important biological activities including the prevention of pathogen binding to the intestinal epithelial and as nutrients for beneficial bacteria. It has been suggested that milk oligosaccharides are an important source of complex carbohydrates as supplements for the food and the pharmaceutical ...
N, Tao, E J, DePeters, S, Freeman, J B, German, R, Grimm, C B, Lebrilla   +5 more
openaire   +2 more sources

Heparan Sulfate Proteoglycans: Master Regulators of Cellular Signaling, Tissue Development, and Neural Function. [PDF]

J Neurosci Res
Ubiquitous cell‐associated, cytoplasmic, synaptic and extracellular matrix HS‐proteoglycans are multifunctional regulators of tissue form and function. HS‐proteoglycans have diverse functions as growth factor co‐receptors in cell proliferation, differentiation, tissue development, mechanical stabilization, synaptogenesis, synaptic plasticity, and ...
Melrose J.
europepmc   +2 more sources

The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design

Scientific Reports, 2017
Human parainfluenza viruses represent a leading cause of lower respiratory tract disease in children, with currently no available approved drug or vaccine.
Larissa Dirr, Ibrahim M. El-Deeb, Leonard M. G. Chavas, Patrice Guillon, Mark von Itzstein   +4 more
doaj   +1 more source

Pneumococcal Phasevarions Control Multiple Virulence Traits, Including Vaccine Candidate Expression

Microbiology Spectrum, 2022
Streptococcus pneumoniae is the most common cause of bacterial illness worldwide. Current vaccines based on the polysaccharide capsule are only effective against a limited number of the >100 capsular serotypes.
Zachary N. Phillips, Claudia Trappetti, Annelies Van Den Bergh, Gael Martin, Ainslie Calcutt, Victoria Ozberk, Patrice Guillon, Manisha Pandey, Mark von Itzstein, W. Edward Swords, James C. Paton, Michael P. Jennings, John M. Atack   +12 more
doaj   +1 more source

MIRAGE: The minimum information required for a glycomics experiment [PDF]

, 2014
The MIRAGE (minimum information required for a glycomics experiment) initiative was founded in Seattle, WA, in November 2011 in order to develop guidelines for reporting the qualitative and quantitative results obtained by diverse types of glycomics ...
Khoo, Kay-Hooi, Costello, Catherine E, Rudd, Pauline M., McBride, R., Haslam, Stuart M., Kettner, C., York, W., Paulson, J. C., Costello, C., Ranzinger, R., Castello, C., Dell, A., Aoki-Kinoshita, K., Campbell, M. P., Rudd, P. M., Kolarich, D., Campbell, Matthew P., Karlsson, Niclas, Costello, Catherine E., Packer, Nicolle H., McBride, Ryan, Campbell, M., Liu, Yan, Packer, Nicolle H, Campbell, Matthew P, Packer, N. H., Rapp, E., Khoo, K. H., Struwe, W. B., Dell, Anne, Feizi, Ten, Rapp, Erdmann, Tiemeyer, M., Agravat, S., Rudd, Pauline M, Paulson, J., Aoki-Kinoshita, Kiyoko F., Kolarich, Daniel, Smith, David F., Zaia, J., Khoo, K., Costello, C. E., Smith, David F, Aoki-Kinoshita, Kiyoko F, Kettner, Carsten, Tiemeyer, Michael, York, William S, Ranzinger, Rene, Packer, N., Struwe, Weston B, Feizi, T., Novotny, M., Paulson, James C, Karlsson, N., Rudd, P., Karlsson, Niclas G.,, York, William S., Karlsson, Niclas G., Struwe, Weston B., Wells, Lance, Agravat, Sanjay, Liu, Y., Novotny, Milos V., Smith, D. F., Haslam, S., Wells, L., Haslam, S. M., Struwe, W., Haslam, Stuart M, Paulson, James C., Campell, F., Novotny, Milos, Zaia, Joseph, Smith, D., York, W. S., Aoki-Kinoshita, K. F.   +75 more
core   +1 more source

A Holistic 4D Approach to Optimize Intrinsic and Extrinsic Factors Contributing to Variability in Microarray Biosensing in Glycomics

Sensors, 2023
Protein–carbohydrate interactions happen to be a crucial facet of biology, discharging a myriad of functions. Microarrays have become a premier choice to discern the selectivity, sensitivity and breadth of these interactions in a high-throughput manner ...
Paras H. Kundalia, Lucia Pažitná, Kristína Kianičková, Eduard Jáné, Lenka Lorencová, Jaroslav Katrlík   +5 more
doaj   +1 more source