Results 21 to 30 of about 11,104 (213)

Glycomics & Glycoproteomics: From Analytics to Function

open access: yes, 2020
Glycomics and glycoproteomics define powerful technologies that help scientists to capture this biological “dark matter” and study all glycans and glycoproteins expressed by cells, tissues or organisms at a given time, space and condition.2–4 While both ...
Packer, Nicolle H   +2 more
core   +1 more source

The glycointeractome of serogroup B Neisseria meningitidis strain MC58

open access: yesScientific Reports, 2017
Neisseria meningitidis express numerous virulence factors that enable it to interact with diverse microenvironments within the host, during both asymptomatic nasopharyngeal colonization and invasive disease.
Tsitsi D. Mubaiwa   +7 more
doaj   +1 more source

Vaccination with chemically attenuated Plasmodium falciparum asexual blood-stage parasites induces parasite-specific cellular immune responses in malaria-naïve volunteers: a pilot study

open access: yesBMC Medicine, 2018
Background The continuing morbidity and mortality associated with infection with malaria parasites highlights the urgent need for a vaccine. The efficacy of sub-unit vaccines tested in clinical trials in malaria-endemic areas has thus far been ...
Danielle I. Stanisic   +14 more
doaj   +1 more source

Streptococcus pyogenes vaccine candidates do not induce autoimmune responses in a rheumatic heart disease model

open access: yesnpj Vaccines, 2023
We have developed a candidate vaccine to protect against multiple strains of Streptococcus pyogenes infections. The candidate vaccine contains two synthetic peptides derived from S. pyogenes proteins: the M-protein epitope, p*17 and the IL-8 degrading S.
Simone Reynolds   +6 more
doaj   +1 more source

The Capricious Nature of Bacterial Pathogens: Phasevarions and Vaccine Development

open access: yesFrontiers in Immunology, 2016
Infectious diseases are a leading cause of morbidity and mortality worldwide, and vaccines are one of the most successful and cost-effective tools for disease prevention.
Aimee Tan   +3 more
doaj   +1 more source

N-glycolylneuraminic acid as a carbohydrate cancer biomarker

open access: yesTranslational Oncology, 2023
One of the forms of aberrant glycosylation in human tumors is the expression of N-glycolylneuraminic acid (Neu5Gc). The only known enzyme to biosynthesize Neu5Gc in mammals, cytidine-5′-monophosphate-N-acetylneuraminic acid (CMAH), appears to be ...
Jing Wang   +3 more
doaj   +1 more source

Advancing glycomics: Implementation strategies at the Consortium for Functional Glycomics [PDF]

open access: yesGlycobiology, 2006
Glycomics-an integrated approach to study structure-function relationships of complex carbohydrates (or glycans)-is an emerging field in this age of post-genomics. Realizing the importance of glycomics, many large scale research initiatives have been established to generate novel resources and technologies to advance glycomics.
Rahul, Raman   +5 more
openaire   +2 more sources

Streptococcus suis Encodes Multiple Allelic Variants of a Phase-Variable Type III DNA Methyltransferase, ModS, That Control Distinct Phasevarions

open access: yesmSphere, 2021
Streptococcus suisS ...
Greg Tram   +7 more
doaj   +1 more source

SSSMuG: Same Sample Sequential Multi-Glycomics

open access: yes
The mammalian glycome is structurally complex and diverse, composed of many glycan classes such as N- and O-linked glycans, glycosaminoglycans (GAGs), glycosphingolipids (GSLs), and other distinct glycan features such as polysialic acids (PolySia ...
Sagar Dalal (17947573)   +5 more
core   +3 more sources

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