Results 111 to 120 of about 49,301 (226)

Whole‐Genome Sequence Profiling of Listeria innocua From Different Sources: Implications for Public Health

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
The studied strains, LIN_NWU_CNKT and LIN5_NWU_CNKT, exhibit invasiveness, pathogenicity, and MDR profiles. The isolation of these strains from food products and water underscores their significant public health implications, particularly in the context of the “One Health” concept.
Christ‐Donald Kaptchouang Tchatchouang, Daniel Jesuwenu Ajose, Giulia Amagliani, Collins Njie Ateba   +3 more
wiley   +1 more source

Design, automated synthesis and immunological evaluation of NOD2-ligand–antigen conjugates

Beilstein Journal of Organic Chemistry, 2014
The covalent attachment of an innate immune system stimulating agent to an antigen can provide active vaccine modalities capable of eliciting a potent immune response against the incorporated antigen.
Marian M. J. H. P. Willems, Gijs G. Zom, Nico Meeuwenoord, Ferry A. Ossendorp, Herman S. Overkleeft, Gijsbert A. van der Marel, Jeroen D. C. Codée, Dmitri V. Filippov   +7 more
doaj   +1 more source

Extracellular and Membrane Protein: Structure, Biological Functions, Diseases, and an Emerging Modality for Drug Discovery

MedComm, Volume 7, Issue 4, April 2026.
Targeted protein degradation represents a paradigm shift from traditional protein inhibition to complete protein elimination. This is achieved through three main strategies for degrading extracellular and membrane proteins: recruitment of cell‐surface LTRs, engagement of intracellular proteins, and receptor‐independent mechanisms.
Mengqing Zhao, Wenhao Yin, Jianjian Han, Huimin Wang, Zheng Liu, Lilong Liu, Wuxiang Mao   +6 more
wiley   +1 more source

Anti-Migration Effects of Gekko Sulfated Glycopeptide on Human Hepatoma SMMC-7721 Cells

Molecules, 2011
Gekko swinhonis Guenther has been used as an anti-cancer drug in traditional Chinese medicine for hundreds of years. Previous studies showed that the Gekko sulfated polysaccharide-protein complex suppressed the proliferation and migration of hepatoma ...
Xiong-Zhi Wu, Dan Chen, Xiao-Qiang Han
doaj   +1 more source

glycopeptides

, 2014
Citation: 'glycopeptides' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.G02656 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial
openaire   +1 more source

Hydrodynamics of the VanA-type VanS histidine kinase: an extended solution conformation and first evidence for interactions with vancomycin [PDF]

, 2017
VanA-type resistance to glycopeptide antibiotics in clinical enterococci is regulated by the VanSARA two-component signal transduction system. The nature of the molecular ligand that is recognised by the VanSA sensory component has not hitherto been ...
AM Stock, AT Ulijasz, C Rayner, CA Potter, CA Potter, CP Zschiedrich, D Kahne, EJ Capra, G Batta, G Werner, GD Wright, H Kinouchi, J Dam, J Grissom-Arnold, JM Creeth, JM Creeth, JP Mackay, JP Waltho, K Koteva, M Arthur, M Arthur, M Arthur, M Arthur, M Baptista, M Baptista, M Jung Kwun, M Nieto, M Rholam, M-C Tseng, MH Lai, N Mani, NE Allen, P Courvalin, P Courvalin, P Groves, P Ma, P Schuck, PE Reynolds, PJ Loll, RB Gillis, RJ Willems, S Ang, S Handwerger, SG Patching, U Gerhard, Y Nakama, Z-G Jia   +46 more
core   +5 more sources

Antimicrobial Effect of Spices and Their Phytochemicals: A Novel Approach to Overcoming Antibiotic Resistance

MedComm, Volume 7, Issue 4, April 2026.
This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva, Yanqi Dai, Shervanthi Homer‐Vanniasinkam, Mohan Edirisinghe   +3 more
wiley   +1 more source

Molecular architecture with carbohydrate functionalized β-peptides adopting 314-helical conformation

Beilstein Journal of Organic Chemistry, 2014
Carbohydrate recognition is essential in cellular interactions and biological processes. It is characterized by structural diversity, multivalency and cooperative effects.
Nitin J. Pawar, Navdeep S. Sidhu, George M. Sheldrick, Dilip D. Dhavale, Ulf Diederichsen   +4 more
doaj   +1 more source

Smart Wearable Ozone Therapy System for Managing Multidrug‐Resistant Wound Infections

Advanced Therapeutics, Volume 9, Issue 3, March 2026.
A smart wearable ozone therapy system enables precise localized ozone delivery directly to the wound bed through integrated ozone generation, real‐time sensing, and controlled air circulation. Controlled ozone exposure disrupts bacterial membranes, enhances antibiotic accessibility, and supports a clinically translatable strategy for managing multidrug‐
Akshay Krishnakumar, Alexander Roth, Praveen Srinivasan, Muhammad Masud Rana, Nicholas L. F. Gallina, Devendra Sarnaik, Robyn R. McCain, Abigail D. Cox, Mohamed N. Seleem, Arun K. Bhunia, Rahim Rahimi   +10 more
wiley   +1 more source

Ninjurin1 in cardiovascular and vascular biology: From molecular mechanisms to therapeutic opportunities

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
NINJ1 mediates PMR in cardiovascular cell death, releasing DAMPs that amplify vascular inflammation. Dual NINJ1 paradox: membrane‐bound form drives endothelial NF‐κB/CXCL‐8 inflammation while soluble form provides atheroprotection. Pericyte NINJ1 regulates the critical balance between angiogenic sprouting and vessel maturation in ischaemic tissues ...
Muhammad Mamunur Rashid Mahib
wiley   +1 more source