Results 121 to 130 of about 75,906 (337)
Biotechnology and Bioengineering, Volume 123, Issue 2, Page 406-419, February 2026.A platform approach to the affinity capture and enrichment of host cell proteins to enable their subsequent deep characterization and elucidation of variants or proteoforms (e.g., molecular size variants, charge variants, glycoforms, etc.). ABSTRACT Removing host cell proteins (HCPs) during biotherapeutic manufacturing is essential to ensure patient ...
Michael E. Dolan +6 more
wiley +1 more source
Identification of Glycopeptides with Multiple Hydroxylysine O-Glycosylation Sites by Tandem Mass Spectrometry [PDF]
, 2015 Glycosylation is one of the most common post-translational modifications in proteins, existing in ∼50% of mammalian proteins. Several research groups have demonstrated that mass spectrometry is an efficient technique for glycopeptide identification ...
Li, Shuai Cheng +6 more
core +2 more sources
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 2, February 2026.ABSTRACT Background Vancomycin (VCM), a first‐line treatment option for infections caused by methicillin‐resistant Staphylococcus aureus, has been reported to cause nephrotoxicity even within therapeutic concentration ranges. Traditional therapeutic drug monitoring strategies rely primarily on the area under the concentration–time curve (AUC), without ...
Yoshihiko Matsuki +6 more
wiley +1 more source
Immunological Evaluation of Recent MUC1 Glycopeptide Cancer Vaccines
Vaccines, 2016 Aberrantly glycosylated mucin 1 (MUC1) is a recognized tumor-specific antigen on epithelial cell tumors. A wide variety of MUC1 glycopeptide anti-cancer vaccines have been formulated by many research groups.
Md Kamal Hossain, K. Wall
semanticscholar +1 more source
Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.The Antarctic Dietzia and Pusillimonas isolates were tested for bioremediation applications. Genomic analyses revealed the potential to degrade complex organic compounds, potential virulence factors and resistance genes. Physiological assays showed a wide range of adaptation to abiotic factors and sensitivity to different groups of antibiotics ...
Tomasz Krucoń +4 more
wiley +1 more source
Analytical and Bioanalytical Chemistry, 2016 Glycopeptide enrichment is a crucial step in glycoproteomics for which hydrophilic interaction chromatography (HILIC) has extensively been applied due to its low bias towards different glycan types.
K. Alagesan, S. K. Khilji, D. Kolarich
semanticscholar +1 more source
Beilstein Journal of Organic Chemistry, 2020 Glycoproteomic data are often very complex, reflecting the high structural diversity of peptide and glycan portions. The use of glycopeptide-centered glycoproteomics by mass spectrometry is rapidly evolving in many research areas, leading to a demand in ...
Steffen Lippold +6 more
doaj +1 more source
The GLV6/RGF8/CLEL2 peptide regulates early pericycle divisions during lateral root initiation [PDF]
, 2015 Small peptides of the Arabidopsis GLV/RGF/CLEL family are involved in different developmental programmes, including meristem maintenance and gravitropic responses.
Beeckman, Tom +6 more
core +4 more sources
Andrology, Volume 14, Issue 2, Page 496-515, February 2026.Abstract Background Lycium barbarum polysaccharide (LBP) has long been recognized as having a wide range of beneficial properties for improving proliferation. However, the protective effects and specific mechanisms of d‐galactose‐induced testicular dysfunction in reproductively senescent rats are not fully understood.
Wenxin Ma +8 more
wiley +1 more source
Design, automated synthesis and immunological evaluation of NOD2-ligand–antigen conjugates
Beilstein Journal of Organic Chemistry, 2014 The covalent attachment of an innate immune system stimulating agent to an antigen can provide active vaccine modalities capable of eliciting a potent immune response against the incorporated antigen.
Marian M. J. H. P. Willems +7 more
doaj +1 more source