Results 71 to 80 of about 23,942 (220)

Escherichia coli susceptible to glycopeptide antibiotics [PDF]

Antimicrobial Agents and Chemotherapy, 1989
Mutants of Escherichia coli susceptible to vancomycin were isolated after mutagenesis with nitrosoguanidine. One such mutant was studied extensively. Multiple regression analysis of the relationship between physical properties of 20 glycopeptides and their in vitro activities against the vancomycin-susceptible mutant revealed a significant correlation ...
D M, Shlaes, J H, Shlaes, J, Davies, R, Williamson   +3 more
openaire   +2 more sources

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

British Journal of Clinical Pharmacology, EarlyView.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst, Pieter‐Jan Spiessens, Dorian Vanneste, Nada Dia, Matthias Gijsen, Isabel Spriet, Karel Allegaert, Erwin Dreesen, Anne Smits   +8 more
wiley   +1 more source

Emerging crisis of multidrug-resistant enterococci from a rural tertiary care hospital of North India

Indian Journal of Health Sciences and Biomedical Research KLEU, 2021
INTRODUCTION: Enterococci are emerging as a major pathogen causing a variety of hospital-acquired nosocomial infections and community-acquired infections contributing significantly to patient's morbidity and mortality.
Jyoti Sangwan, Kirti Lohan, Pratibha Mane, Mukesh Kumar   +3 more
doaj   +1 more source

Glycopeptide resistance in enterococci [PDF]

, 2010
The selective pressure resulting from the extensive use of antibiotics over the last 50 years has led to the emergence of bacterial resistance and to the dissemination of resistance genes among pathogenic microorganisms.
Félix Claverie-Martín, Sebastián Méndez-Álvarez, Xiomara Pérez-Hernández   +2 more
core   +2 more sources

Tomato prosystemin gene in other Solanaceae [PDF]

, 2009
Systemin, an octadeca-peptide isolated from tomato, is a signalling molecule involved in local and systemic wound response. It regulates the activation of more than twenty defensive genes in tomato plants in response to herbivore attacks.
Araujo Burgos, Tania
core   +1 more source

In Vitro Characterization of Technological and Health‐Promoting Properties of Enterocin Producing Lactic Acid Bacteria From Camel Milk and Its Suitability as a Dairy Starter

Food Chemistry International, EarlyView.
Enterocin‐producing Enterococcus faecium RSCUDR7 from camel milk exhibited strong probiotic and antimicrobial properties, along with stability in skim milk. Its suitability as a safe and effective dairy starter highlights its potential for developing functional probiotic dairy products.
Rahul Singhal, Kamalesh Kumar Meena, Manvik Joshi, Lokesh Gupta, Sunil Meena   +4 more
wiley   +1 more source

Antiviral activity of glycopeptide antibiotics derivates against Sindbis virus

International Journal of Infectious Diseases
Introduction: Thousands of human infective viruses spread worldwide, yet protective measures exist for only a fraction, with internationally accepted vaccines available for an even smaller subset.
Ms Krisztina Leiner, Mr Valentin Molnár, Mr Zoltán Kopasz, Mrs Ilona Bakai-Bereczki, Ms Eszter Lőrincz, Dr. Eszter Szabó, Dr. Mónika Madai, Dr. Anikó Borbás, Dr. Anett Kuczmog   +8 more
doaj   +1 more source

Antibiotic Remodeling of the Gut Microbiota Impairs Host Resistance to Secondary Infection

iMetaMed, EarlyView.
Gut microbial dynamics induced by four antibiotics, revealed distinct taxonomic and functional shifts. Vancomycin‐perturbed bacteriomes were proven to promote pathogen resistance to antibiotic treatment. Metronidazole‐treated mice showed pronounced Salmonella translocation to hepatic tissue, and altered Enterococcus avium populations modulated host ...
Miaoyu Li, Ying Chen, Xi Chen, Weili Lu, Jie Liao, Jiaqi Wang, Qiwei Liu, Yanzi Chang, Zeping Xu, Yanye Tu, Yang Zhou, Jing Xue, Binbin Wang, Kang Chen, Keyun Cheng, Chunlai Zeng, Hong Li, Qing Shen   +17 more
wiley   +1 more source

VanZ Reduces the Binding of Lipoglycopeptide Antibiotics to Staphylococcus aureus and Streptococcus pneumoniae Cells

Frontiers in Microbiology, 2020
vanZ, a member of the VanA glycopeptide resistance gene cluster, confers resistance to lipoglycopeptide antibiotics independent of cell wall precursor modification by the vanHAX genes.
Vladimir Vimberg, Leona Zieglerová, Karolína Buriánková, Pavel Branny, Gabriela Balíková Novotná   +4 more
doaj   +1 more source

Synthesis of an amphiphilic vancomycin aglycone derivative inspired by polymyxins: overcoming glycopeptide resistance in Gram-positive and Gram-negative bacteria in synergy with teicoplanin in vitro

Scientific Reports, 2022
Gram-negative bacteria possess intrinsic resistance to glycopeptide antibiotics so these important antibacterial medications are only suitable for the treatment of Gram-positive bacterial infections.
Zsolt Szűcs, Ilona Bereczki, Ferenc Fenyvesi, Pál Herczegh, Eszter Ostorházi, Anikó Borbás   +5 more
doaj   +1 more source