Protein O-Mannosylation in the Murine Brain: Occurrence of Mono-O-Mannosyl Glycans and Identification of New Substrates [PDF]
, 2016 Protein O-mannosylation is a post-translational modification essential for correct development of mammals. In humans, deficient O-mannosylation results in severe congenital muscular dystrophies often associated with impaired brain and eye development ...
Bartels, MF +10 more
core +5 more sources
Tomato prosystemin gene in other Solanaceae [PDF]
, 2009 Systemin, an octadeca-peptide isolated from tomato, is a signalling molecule involved in local and systemic wound response. It regulates the activation of more than twenty defensive genes in tomato plants in response to herbivore attacks.
Araujo Burgos, Tania
core +1 more source
Molecular Basis of Non-β-Lactam Antibiotics Resistance in Staphylococcus aureus
Antibiotics, 2022 Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most successful human pathogens with the potential to cause significant morbidity and mortality.
Harshad Lade +2 more
doaj +1 more source
Characterization of Cell Glycocalyx with Mass Spectrometry Methods. [PDF]
, 2019 The cell membrane plays an important role in protecting the cell from its extracellular environment. As such, extensive work has been devoted to studying its structure and function.
Lebrilla, Carlito B +3 more
core +2 more sources
Frontiers in Chemistry, 2021 Reversible protein glycosylation and phosphorylation tightly modulate important cellular processes and are closely involved in pathological processes in a crosstalk dependent manner.
Cheng Chen +8 more
doaj +1 more source
Mapping the complete glycoproteome of virion-derived HIV-1 gp120 provides insights into broadly neutralizing antibody binding [PDF]
, 2016 The surface envelope glycoprotein (SU) of Human immunodeficiency virus type 1 (HIV-1), gp120SU plays an essential role in virus binding to target CD4+ T-cells and is a major vaccine target.
Bess, JW +15 more
core +1 more source
Identification of novel chondroitin proteoglycans in Caenorhabditis elegans: embryonic cell division depends on CPG-1 and CPG-2. [PDF]
, 2006 Vertebrates produce multiple chondroitin sulfate proteoglycans that play important roles in development and tissue mechanics. In the nematode Caenorhabditis elegans, the chondroitin chains lack sulfate but nevertheless play essential roles in embryonic ...
Bishop, Joseph R +4 more
core +2 more sources
mBio, 2019 The physiological role of protein O-glycosylation in prokaryotes is poorly understood due to our limited knowledge of the extent of their glycoproteomes.
Tessa Keenan +3 more
doaj +1 more source
Glycopeptide Antibiotic Resistance Genes in Glycopeptide-Producing Organisms [PDF]
Antimicrobial Agents and Chemotherapy, 1998 ABSTRACT The mechanism of high-level resistance to vancomycin in enterococci consists of the synthesis of peptidoglycan terminating in d -alanyl- d -lactate instead of the usual d -alanyl- d -alanine.
C G, Marshall +3 more
openaire +2 more sources
A bivalent glycopeptide to target two putative carbohydrate binding sites on FimH
Beilstein Journal of Organic Chemistry, 2010 FimH is a mannose-specific bacterial lectin found on type 1 fimbriae with a monovalent carbohydrate recognition domain (CRD) that is known from X-ray studies.
Thisbe K. Lindhorst +3 more
doaj +1 more source