Results 61 to 70 of about 582,559 (301)

Functional differences among the spike glycoproteins of multiple emerging severe acute respiratory syndrome coronavirus 2 variants of concern

iScience, 2021
Summary: We compared the functional properties of spike (S) glycoproteins from the original SARS-CoV-2 strain (D614) (Wuhan, China), the globally dominant D614G strain, and emerging geographic variants: B.1.1.7 (United Kingdom), B.1.351 (South Africa), P.
Qian Wang, Manoj S. Nair, Saumya Anang, Shijian Zhang, Hanh Nguyen, Yaoxing Huang, Lihong Liu, David D. Ho, Joseph G. Sodroski   +8 more
doaj   +1 more source

Expression of the murine cytomegalovirus glycoprotein H by recombinant vaccinia virus [PDF]

, 1994
The sequence of the gene encoding glycoprotein H (gH) of murine cytomegalovirus (MCMV) strain Smith was determined and compared with the sequence of the gH of MCMV strain K181. Transcriptional analysis showed that gH is encoded by a large mRNA of 5.0 kb,
Rapp, Maria, Koszinowski, Ulrich H., Lucin, Pero, Messerle, Martin, Loh, Lambert C.   +4 more
core  

Blocking Variant Surface Glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation

, 2009
Background: The African trypanosome Trypanosoma brucei is covered with a dense layer of Variant Surface Glycoprotein (VSG), which protects it from lysis by host complement via the alternative pathway in the mammalian bloodstream.
Gluenz, E, Rudenko, G, Gluenz Eva, Terry K Smith, Shulamit Michaeli, Susanne Kramer, Michaeli, Shulamit, Terry, Stephen, Terry K. Smith, Michaeli, S, Eva Gluenz, Smith, Terry K., Vasileva, N, Nadina Vasileva, Mark Carrington, Michaeli Shulamit, Vasileva, Nadina, Carrington, M, Stephen Terry, Rudenko Gloria, Gull Keith, Portman, N, Gluenz, Eva, Keith Gull, Terry, S, Smith Terry K., Neil Portman, Gull, K, Kramer, S, Portman, Neil, Smith, TK, Smith, Terry K, Rudenko, Gloria, Terry Stephen, Vasileva Nadina, Gull, Keith, Carrington Mark, Carrington, Mark, Kramer, Susanne, Terry K. Smith, Portman Neil, Kramer Susanne, Gloria Rudenko   +42 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Pseudorabies Virus Glycoproteins E and B Application in Vaccine and Diagnosis Kit Development

Vaccines
Background: Pseudorabies virus (PRV) is a highly infectious pathogen that affects a wide range of mammals and imposes a significant economic burden on the global pig industry.
Sara Amanuel Bude, Zengjun Lu, Zhixun Zhao, Qiang Zhang   +3 more
doaj   +1 more source

In vivo evidence for quasispecies distributions in the bovine respiratory syncytial virus genome [PDF]

, 2007
We analyzed the genetic evolution of bovine respiratory syncytial virus (BRSV) isolate W2-00131, from its isolation in bovine turbinate (BT) cells to its inoculation in calves.
Mirandette, Carole, Schelcher, François, Bonnet, Marion, Meyer, Gilles, Deplanche, Martine, Lemaire, Mylène   +5 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Optimization of PCR-ELISA in Detection of Human Cytomegalovirus Infection

Medical Laboratory Journal, 2015
Background and Objective: Human Cytomegalovirus (CMV) is an important cause of congenital viral infection that can lead to serious diseases and complications in infants.
M Talkhabifard, M, N Javid, N, A Moradi, A, A Ghaemi, A, A Tabarraei, A   +4 more
doaj  

Matrix Glycoprotein SC1/ECM2 Augments B Lymphopoiesis [PDF]

Blood, 1997
AbstractThe extracellular matrix produced by stromal cells plays a critical role in lympho-hematopoiesis. It was recently discovered that matrix glycoprotein SC1/ECM2 is a component of that matrix and preliminary evidence suggested that it could contribute to the nurturing environment for B-lymphocyte precursors.
K, Oritani, Y, Kanakura, K, Aoyama, T, Yokota, N G, Copeland, D J, Gilbert, N A, Jenkins, Y, Tomiyama, Y, Matsuzawa, P W, Kincade   +9 more
openaire   +2 more sources