Results 111 to 120 of about 154,508 (334)

Establishment of Glycosaminoglycan Assays for Mucopolysaccharidoses

Metabolites, 2014
Mucopolysaccharidoses (MPS) are a group of lysosomal storage disorders caused by deficiency of the lysosomal enzymes essential for catabolism of glycosaminoglycans (GAGs).
S. Tomatsu, T. Shimada, R. Mason, Adriana M. Montaño, J. Kelly, W. Lamarr, Francyne Kubaski, R. Giugliani, A. Guha, Eriko Yasuda, W. Mackenzie, S. Yamaguchi, Yasuyuki Suzuki, T. Orii   +13 more
semanticscholar   +1 more source

Zinc‐Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun, XueBo Wei, ZhuoYang Song, JunJun Luo, JingYi Ye, YinNan Zhang, LiFei Zhu, Jie Gao, Hongyu Zhang, Hong Zhu, Xin Wang, Ke Xu   +11 more
wiley   +1 more source

Galactosaminoglycans from normal myometrium and leiomyoma

Brazilian Journal of Medical and Biological Research, 2001
In many tumors, the amount of chondroitin sulfate in the extracellular matrix has been shown to be elevated when compared to the corresponding normal tissue. Nevertheless, the degree of chondroitin sulfate increase varies widely.
A.G.A. Berto, S.M. Oba, Y.M. Michelacci, L.O. Sampaio   +3 more
doaj   +1 more source

Osteoprotegerin reduces osteoclast resorption activity without affecting osteogenesis on nanoparticulate mineralized collagen scaffolds. [PDF]

, 2019
The instructive capabilities of extracellular matrix-inspired materials for osteoprogenitor differentiation have sparked interest in understanding modulation of other cell types within the bone regenerative microenvironment.
Bischoff, David, Dewey, Marley J, Foulad, David, Harley, Brendan AC, He, Tong-Chuan, Lee, Justine C, Miller, Timothy A, Reid, Russell R, Ren, Xiaoyan, Tiffany, Aleczandria S, Yamaguchi, Dean T, Zhou, Qi   +11 more
core  

PiP‐Plex: A Particle‐in‐Particle System for Multiplexed Quantification of Proteins Secreted by Single Cells

Advanced Materials, EarlyView.
Detecting proteins secreted by a single cell while retaining its viability remains challenging. A particles‐in‐particle (PiPs) system made by co‐encapsulating barcoded microparticles (BMPs) with a single cell inside an alginate hydrogel particle is introduced.
Félix Lussier, Byeong‐Ui Moon, Mojra Janta‐Polczynski, Yonatan Morocz, Fabian Svahn, Molly Shen, Ljuboje Lukic, Lidija Malic, Teodor Veres, Andy Ng, David Juncker   +10 more
wiley   +1 more source

Attenuation of arsenic-induced gut injury in mice by sulfated glycosaminoglycan from swim bladder via regulation of gut microbiota, metabolites, and intestinal barrier integrity

Food Science and Human Wellness
Arsenic, a known environmental carcinogen, disrupts intestinal homeostasis, posing a significant threat to human health. Mitigating its toxic effects is crucial, and this study explores the potential of swim bladder sulfated glycosaminoglycan (SBSG) in ...
Jieying Ou, Xiaofei Liu, Jing Chen, Houpei Huang, Xuejing Jia, Baojun Xu, Zhi-Ling Yu, Saiyi Zhong   +7 more
doaj   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Incorporation of heparin-binding proteins into preformed dextran sulfate-chitosan nanoparticles

International Journal of Nanomedicine, 2016
Paula Zaman,1 Julia Wang,1 Adam Blau,1 Weiping Wang,2 Tina Li,1 Daniel S Kohane,2 Joseph Loscalzo,1 Ying-Yi Zhang1 1Department of Medicine, Brigham and Women’s Hospital, 2Department of Anesthesiology, Boston Children’s Hospital, Harvard ...
Zaman P, Wang J, Blau A, Wang W, Li T, Kohane DS, Loscalzo J, Zhang YY   +7 more
doaj  

Overview of the Mechanisms that May Contribute to the Non-Redundant Activities of Interferon-Inducible CXC Chemokine Receptor 3 Ligands

Frontiers in Immunology, 2018
The inflammatory chemokines CXCL9, CXCL10, and CXCL11 are predominantly induced by interferon (IFN)-γ and share an exclusive chemokine receptor named CXC chemokine receptor 3 (CXCR3).
Mieke Metzemaekers, Vincent Vanheule, Rik Janssens, Sofie Struyf, Paul Proost   +4 more
doaj   +1 more source

Crosslinking and Mechanical Properties Significantly Influence Cell Attachment, Proliferation, and Migration Within Collagen Glycosaminoglycan Scaffolds

Tissue Engineering. Part A, 2011
Crosslinking and the resultant changes in mechanical properties have been shown to influence cellular activity within collagen biomaterials. With this in mind, we sought to determine the effects of crosslinking on both the compressive modulus of collagen-
M. Haugh, C. Murphy, R. C. McKiernan, Cornelia Altenbuchner, F. O'Brien   +4 more
semanticscholar   +1 more source