Results 101 to 110 of about 90,028 (262)

Glycosaminoglycan (GAG) binding surfaces for characterizing GAG-protein interactions

, 2012
Glycosaminoglycan (GAG) binding surfaces for characterizing GAG-protein ...
RD Short (19462054), DJ Buttle (19462051), JD Whittle (19448392), Sally McArthur (13226361), DA Steele (15964880), DE Robinson (19462048)   +5 more
core  

Cardiac morphological and morphometric analysis of Ardea alba

The Anatomical Record, EarlyView.
Abstract Ardea alba (Linnaeus, 1758) is a widely distributed heron species whose cardiovascular morphology remains poorly described. This study aimed to characterize the cardiac morphology and morphometry of adult A. alba. Ten specimens were analyzed using radiographic, morphometric, histological, scanning electron microscopy, and three‐dimensional ...
Julia Vaz Feio, Max Alex Santos Ferreira, Elane Guerreiro Giese, Érika Branco, Antônio Basílio Guerreiro Junior, Ana Rita de Lima   +5 more
wiley   +1 more source

Overview of the Mechanisms that May Contribute to the Non-Redundant Activities of Interferon-Inducible CXC Chemokine Receptor 3 Ligands

Frontiers in Immunology, 2018
The inflammatory chemokines CXCL9, CXCL10, and CXCL11 are predominantly induced by interferon (IFN)-γ and share an exclusive chemokine receptor named CXC chemokine receptor 3 (CXCR3).
Mieke Metzemaekers, Vincent Vanheule, Rik Janssens, Sofie Struyf, Paul Proost   +4 more
doaj   +1 more source

Morphological description of the oropharyngeal cavity of Kinosternon scorpioides scorpioides (Linnaeus, 1766), (Testudines: Kinosternidae)

The Anatomical Record, EarlyView.
Gross morphology, Light Microscopy and Scanning Electron Microscopy revealed the structural organization of the oropharyngeal cavity of Kinosternon scorpioides scorpioides, characterized by mucous epithelium, epithelial pores, and developed lingual papillae.
Andréa Magalhães Bezerra, Diego Ferreira de Sousa, Luane Botelho, André Luís Nogueira Lima, Érika Branco, Elane Guerreiro Giese, Washington Luís Pereira, Ana Rita de Lima   +7 more
wiley   +1 more source

Intravesical hyaluronic acid and chondroitin sulphate for recurrent urinary tract infections: a prospective multicentre comparison of two instillation protocols

Frontiers in Surgery
BackgroundRecurrent urinary tract infections (r-UTIs) are highly prevalent in women and are associated with reduced quality of life and increased healthcare burden.
Marilena Gubbiotti, Alessandro Giammò, Enrico Ammirati, Annarita Cicalese, Elisabetta Costantini, Ester Illiano, Vincenzo Li Marzi, Mara Bacchiani, Leonardo Martino, Vito Mancini, Stefano Rosadi   +10 more
doaj   +1 more source

Increase in glycosaminoglycan synthesis in familial hypercholesterolemic fibroblasts.

, 1985
The enzymes of biosynthesis are usually bound to membranes and require an undisturbed lipid environment for regulated activity. In familial hypercholesterolemia, this lipid environment is disturbed and there is a low cholesterol ester level in the ...
N Zöllner, A J Wieczorek
core   +1 more source

The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho‐Associated Protein Kinase–Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang, Lichong Shen, Junhui Zheng, Gisela Baur, Dilidaer Yasen, Honglin Zhu, Yi‐Nan Li, Xianyi Meng, Thuong Trinh‐Minh, Tim Filla, Debomita Chakraborty, Andrea‐Hermina Györfi, Christina Bergmann, Adam Reich, Alexander Kreuter, Georg Schett, Jörg H. W. Distler   +16 more
wiley   +1 more source

Glycosaminoglycan-induced activation of the β-secretase (BACE1) of Alzheimer's disease

, 2010
The b-site APP cleaving enzyme (BACE1) is responsible for the first step in the production of the b-amyloid protein of Alzheimer’s disease. BACE1 is synthesized as a partially active zymogen (proBACE1). We previously showed that the glycosaminoglycan
Klaver, DW (15531932), Lisa Foa (14736694), Freeman, C (15526505), David Small (14749594), Aguilar, MI (15518651), Robert Gasperini (14737258), Parish, C (15531941), Juliano, JP (15531938), Wilce, MCJ (15531935)   +8 more
core  

Thin Layer Chromatography for the Analysis of Glycosaminoglycan Oligosaccharides

, 2007
Analytical Biochemistry, 371, 118–120Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY.
Linhardt, Robert J., Zhang, Fuming, Xie, Jin, Zhang, Zhenqing   +3 more
core   +1 more source

CD248/Endosialin Regulates Synovial Fibroblast State to Control Coupling of Inflammation and Bone Damage in Murine Models of Immune‐Mediated Inflammatory Arthritis and Aging

Arthritis &Rheumatology, EarlyView.
Objective Synovial fibroblasts directly contribute to inflammation and damage in immune‐mediated inflammatory arthritis. CD248/endosialin is expressed by fibroblasts in the synovium, is highly up‐regulated during inflammation, and has been proposed as a potential therapeutic target.
Samuel Kemble, Corinna Wehmeyer, James M. Brown, Charlotte G. Smith, Holly R. Adams, Eva Crombie, Ellie Northall, Maryam Imran, Paulynn Chin, Harris R. Perlman, Christopher D. Buckley, Adam P. Croft, Amy J. Naylor   +12 more
wiley   +1 more source