Results 111 to 120 of about 90,028 (262)

Glycosaminoglycan-mediated leuserpin-2/thrombin interaction: structure-function relationships

, 1990
Ragg H, Ulshöfer T, Gerewitz J. Glycosaminoglycan-mediated leuserpin-2/thrombin interaction: structure-function relationships. J. Biol. Chem.
Ragg, Hermann, Ulshöfer, Thomas, Gerewitz, Jutta   +2 more
core  

Glycosaminoglycan supplementation promotes nerve regeneration and muscle reinnervation

, 1997
This study shows that treatment of rats with exogenous glycosaminoglycans stimulates peripheral nerve regeneration, increases the abundance of mRNAs for myelin proteins and promotes muscle reinnervation, After the sciatic nerve had been crushed the ...
L. Vergani, E. Lesma, A. Gorio, A. Di Giulio   +3 more
core   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source

The glycosaminoglycan-binding chemokine fragment CXCL9(74–103) reduces inflammation and tissue damage in mouse models of coronavirus infection

Frontiers in Immunology
IntroductionPulmonary diseases represent a significant burden to patients and the healthcare system and are one of the leading causes of mortality worldwide.
Vivian Louise Soares Oliveira, Vivian Louise Soares Oliveira, Celso Martins Queiroz-Junior, Delphine Hoorelbeke, Felipe Rocha da Silva Santos, Ian de Meira Chaves, Mauro Martins Teixeira, Remo de Castro Russo, Paul Proost, Vivian Vasconcelos Costa, Sofie Struyf, Flávio Almeida Amaral   +11 more
doaj   +1 more source

Percentage of disaccharides products formed by the action of chondroitinase AC on glycosaminoglycan of human lumbar intervertebral disc.

, 2018
Percentage of disaccharides products formed by the action of chondroitinase AC on glycosaminoglycan of human lumbar intervertebral disc.
Rejane Daniele Reginato (5759294), Flavio Faloppa (5759300), Marcelo Lima (5759291), Valquiria Pereira de Medeiros (5759285), Marcelo Wajchenberg (5759288), Edgar Julian Paredes-Gamero (422936), Eduardo Barros Puertas (5759297), Delio Eulalio Martins (5759282), Helena Bonciani Nader (409298)   +8 more
core   +1 more source

Magnetoelastic Cell Monitoring System for Evaluating the Effects of Surface Chemistry on the Performance of Mesenchymal Stem Cell Growth

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The recent clinical adoption of cell therapies has increased the need for more efficient, robust, and reproducible manufacturing technologies. Human mesenchymal stromal cells (hMSCs), a major component of the cell and immunotherapeutic market, remain challenging to manufacture at scale because they require surface attachment and are highly ...
William S. Skinner, Carolina Rivera‐Crespo, Eyerusalem A. Gebreyesus, Said Cifuentes, Samantha Tan, Tristen Douglas, Maribella Domenech‐Garcia, Keat Ghee Ong   +7 more
wiley   +1 more source

Enzymatic Polymerization to Artificial Hyaluronan:  A Novel Method to Synthesize a Glycosaminoglycan Using a Transition State Analogue Monomer

, 2016
Enzymatic Polymerization to Artificial Hyaluronan:  A Novel Method to Synthesize a Glycosaminoglycan Using a Transition State Analogue ...
Shiro Kobayashi (355356), Ryosuke Itoh (2987433), Masashi Ohmae (2488978), Shunsaku Kimura (1408714), Hidekazu Morii (2987436)   +4 more
core   +1 more source

Isolating T‐Cell Potent Lentiviral Vector Subpopulations through Rational Design of Nanofiber Anion‐Exchange Adsorbents

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Generation of CAR‐T cell therapies relies predominantly on lentiviral vectors (LVs). As in vivo CAR‐T trials progress, demand for larger quantities of higher‐potency LV is expected. However, primary capture by anion‐exchange chromatography (AIEX) remains a major manufacturing bottleneck from use of adsorbents not tailored to LVs, leading to ...
George Pamenter, Gyorgy Ovari, Anurag Kulkarni, Thomas Williams‐Fegredo, Carol Knevelman, Kyriacos Mitrophanous, Lee Davies, Farzad Foroutan, Matthew Townsend, Stephen Goldrick, Daniel G. Bracewell   +10 more
wiley   +1 more source

Improved Detection of Polysulfated Oligosaccharides by Mass Spectrometry Applicable to Miniaturized Samples

Molecules
The study of biomolecules and their interactions in their natural environment requires increasingly sophisticated technological and methodological developments.
Frédéric Jeanroy, Julie Gil, Clothilde Comby-Zerbino, Claire Demesmay, Vincent Dugas   +4 more
doaj   +1 more source

Disaccharide analysis of glycosaminoglycan mixtures by ultra-performance liquid chromatography-mass spectrometry

, 2012
Journal of Chromatography A,1225, 91– 98Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY.
Weyers, A.M., Linhardt, Robert J., Chang, Y., Yang, B., Sterner, E.   +4 more
core   +1 more source