Results 291 to 300 of about 154,508 (334)

Changes in glycosaminoglycan concentration and synovial permeability at raised intra‐articular pressure in rabbit knees.

, 1996
Frank Price, J. R. Levick, Roger M. Mason   +2 more
openalex   +2 more sources

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

The FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Equine Bone Marrow-Derived MSCs and Their EVs Exhibit Different Immunomodulatory Effects on Cartilage Explants in an <i>In Vitro</i> Osteoarthritis Model. [PDF]

Cartilage
Gaesser AM, Cianci JM, Even K, Linardi RL, Ruthel G, Barot D, Elkhenany H, Engiles JB, Ortved KF.   +8 more
europepmc   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Biomarkers of Microcirculatory Dysfunction in Sepsis: A Pilot Prospective Observational Study. [PDF]

Crit Care Explor
Longino A, Martin K, Bourland S, Phinney W, Wood T, Camargo E, Garcia A, Oakes J, Hiller T, Weiss R, Basu A, Douglas I, Hippensteel J.   +12 more
europepmc   +1 more source

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

The FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola, Deianira Bellitto, Erfan Asgari, Virginia Bazzurro, Giorgia Casucci, Francesco Piacente, Matteo Bozzo, Davide Ceresa, Costantino Parisi, Cecilia Winata, Simona Candiani, Michela Tonetti   +11 more
wiley   +1 more source

The Glycosaminoglycan-Dependent Interactome of Neurexin-1 in Human Fetal Glial Cells. [PDF]

Proteoglycan Res
Critcher M, Wu H, Lu Y, Huang ML.
europepmc   +1 more source

Arylsulfatase LvArs2 regulates glycosaminoglycan sulfation and modulates white spot syndrome virus burden in Litopenaeus vannamei

Fajun Jiang, Chuhang Cheng, Tianyi Shen, Shella Li, huteng he   +4 more
openalex   +1 more source

RNF13 is a previously undescribed interactor of iduronate 2‐sulfatase that modifies its glycosylation and maturation

The FEBS Journal, EarlyView.
Iduronate 2‐sulfatase (IDS; purple) is expressed as a precursor protein that goes through multiple steps of maturation, modification, and trafficking to become an active lysosomal enzyme that degrades glycosaminoglycans. Our study shows that the transmembrane ubiquitin ligases RNF13 (orange) and RNF167 (pink) heterodimerize, affecting IDS intracellular
Valérie C. Cabana, Antoine Y. Bouchard, Audrey M. Sénécal, Laurent Cappadocia, Marc P. Lussier   +4 more
wiley   +1 more source

Glycosaminoglycans Targeted by Colchicine in MCF-7 Cells. [PDF]

Pharmaceutics
Czarnecka-Czapczyńska M, Przygórzewska A, Dynarowicz K, Bartusik-Aebisher D, Aebisher D, Kawczyk-Krupka A.   +5 more
europepmc   +1 more source