Glycosaminoglycans and Contrast Agents: The Role of Hyaluronic Acid as MRI Contrast Enhancer
Biomolecules, 2020 A comprehensive understanding of the behaviour of Glycosaminoglycans (GAGs) combined with imaging or therapeutic agents can be a key factor for the rational design of drug delivery and diagnostic systems.
Alfonso Maria Ponsiglione +2 more
doaj +1 more source
Chemokine CXCL1 mediated neutrophil recruitment: Role of glycosaminoglycan interactions
Scientific Reports, 2016 The chemokine CXCL1/MGSA plays a pivotal role in the host immune response by recruiting and activating neutrophils for microbial killing at the tissue site.
Kirti V. Sawant +6 more
semanticscholar +1 more source
Proton Conductivity of Glycosaminoglycans [PDF]
PLOS ONE, 2018 AbstractProton (H+) conductivity is important in many natural phenomena including oxidative phosphorylation in mitochondria and archea, uncoupling membrane potentials by the antibiotic Gramicidin, and proton actuated bioluminescence in dinoflagellate.
Selberg, John +2 more
openaire +4 more sources
The Development of Assays for Heparanase Enzymatic Activity: Towards a Gold Standard
Molecules, 2018 The enzyme heparanase, an endo-β-glucuronidase, degrades heparan sulfate (HS) chains on the cell surface and in the extracellular matrix. Heparanase regulates numerous biological processes that drive tumour growth, metastasis and angiogenesis.
Mohit Chhabra, Vito Ferro
doaj +1 more source
Glycosaminoglycan Modification of Decorin Depends on MMP14 Activity and Regulates Collagen Assembly
Cells, 2020 Proper processing of collagens COL1 and COL6 is required for normal function of adipose tissue and skeletal muscle. Proteoglycan decorin (DCN) regulates collagen fiber formation.
Alexes C. Daquinag +4 more
doaj +1 more source
MatrixDB: integration of new data with a focus on glycosaminoglycan interactions
Nucleic Acids Res., 2018 MatrixDB (http://matrixdb.univ-lyon1.fr/) is an interaction database focused on biomolecular interactions established by extracellular matrix (ECM) proteins and glycosaminoglycans (GAGs).
O. Clerc +7 more
semanticscholar +1 more source
Glycosaminoglycan Functionalized Nanoparticles Exploit Glycosaminoglycan Functions [PDF]
, 2014 Nanoparticles are being explored for a variety of applications including medical imaging, drug delivery, and biochemical detection. Surface functionalization of nanoparticles with glycosaminoglycans (GAGs) is an attractive strategy that is only starting to be investigated to improve their properties for biological and therapeutic applications.
Vassie, JA, Whitelock, JM, Lord, MS
openaire +3 more sources
PI3K/Akt Signaling Involved with Osteoinductive Effects of Achatina fulica Mucus [PDF]
Brazilian Archives of Biology and Technology, 2020 Mesenchymal stem cells and osteoblasts play important roles in bone formation. Achatina fulica mucus presented the property of osteoinduction. This study aimed to examine the effects of A.
Fahsai Kantawong +7 more
doaj +2 more sources
Interstitial Fluid in Lipedema and Control Skin
Women's Health Reports, 2020 Background: Fluid in lymphedema tissue appears histologically as spaces around vessels and between dermal skin fibers. Lipedema is a painful disease of excess loose connective tissue (fat) in limbs, almost exclusively of women, that worsens by stage ...
Marisol Allen +2 more
doaj +1 more source
Glycosaminoglycan Interactions with Chemokines Add Complexity to a Complex System
Pharmaceuticals, 2017 Chemokines have two types of interactions that function cooperatively to control cell migration. Chemokine receptors on migrating cells integrate signals initiated upon chemokine binding to promote cell movement.
A. Proudfoot +3 more
semanticscholar +1 more source