Effect of epithelial debridement on human cornea proteoglycans
Brazilian Journal of Medical and Biological Research, 2001 Corneal transparency is attributed to the regular spacing and diameter of collagen fibrils, and proteoglycans may play a role in fibrillogenesis and matrix assembly. Corneal scar tissue is opaque and this opacity is explained by decreased ultrastructural
E.S. Soriano +3 more
doaj +1 more source
Glycosaminoglycans and Contrast Agents: The Role of Hyaluronic Acid as MRI Contrast Enhancer
Biomolecules, 2020 A comprehensive understanding of the behaviour of Glycosaminoglycans (GAGs) combined with imaging or therapeutic agents can be a key factor for the rational design of drug delivery and diagnostic systems.
Alfonso Maria Ponsiglione +2 more
doaj +1 more source
Molecular Therapy: Methods & Clinical Development, 2017 Sanfilippo syndrome type B (mucopolysaccharidosis IIIB), caused by inherited deficiency of α-N-acetylglucosaminidase (NAGLU), required for lysosomal degradation of heparan sulfate (HS), is a pediatric neurodegenerative disorder with no approved treatment.
Mika Aoyagi-Scharber +24 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2020 Self-propagating form of the prion protein (PrPSc) causes many neurodegenerative diseases, such as Creutzfeldt-Jakob disease (CJD) and Gerstmann-Straussler-Scheinker syndrome (GSS).
So Young Kim +5 more
doaj +1 more source
Impact of bidirectional relationships between streptococcus anginosus group and host tissue matrix components on cellular activity: Role in establishment of infection [PDF]
, 2003 This paper investigates pathogenic mechanisms of the Streptococcus anginosus group (SAG) of bacteria which influence the biological activity of periodontal ligament (PDL) cells, endothelial cells and also how matrix proteins produced by these host cells ...
Waddington, Rachel J. +4 more
core +10 more sources
Interstitial Fluid in Lipedema and Control Skin
Women's Health Reports, 2020 Background: Fluid in lymphedema tissue appears histologically as spaces around vessels and between dermal skin fibers. Lipedema is a painful disease of excess loose connective tissue (fat) in limbs, almost exclusively of women, that worsens by stage ...
Marisol Allen +2 more
doaj +1 more source
Chondrodysplasias With Multiple Dislocations Caused by Defects in Glycosaminoglycan Synthesis
Frontiers in Genetics, 2021 Chondrodysplasias with multiple dislocations form a group of severe disorders characterized by joint laxity and multiple dislocations, severe short stature of pre- and post-natal onset, hand anomalies, and/or vertebral anomalies.
Johanne Dubail +2 more
doaj +1 more source
Glycosaminoglycans in the human cornea: age-related changes [PDF]
, 2015 AIM: To investigate possible age-related changes in glycosaminoglycans (GAGs) in the human cornea. The substances today called GAGs were previously referred to as mucopolysaccharides.
Anello, Giulia +6 more
core +2 more sources
PI3K/Akt Signaling Involved with Osteoinductive Effects of Achatina fulica Mucus [PDF]
Brazilian Archives of Biology and Technology, 2020 Mesenchymal stem cells and osteoblasts play important roles in bone formation. Achatina fulica mucus presented the property of osteoinduction. This study aimed to examine the effects of A.
Fahsai Kantawong +7 more
doaj +2 more sources
Enhanced Tissue Integration During Cartilage RepairIn VitroCan Be Achieved by Inhibiting Chondrocyte Death at the Wound Edge [PDF]
, 2009 Objective: Experimental wounding of articular cartilage results in cell death at the lesion edge. The objective of this study was to investigate whether inhibition of this cell death results in enhanced integrative cartilage repair.
Archer, Charles W. +7 more
core +1 more source