Results 211 to 220 of about 53,525 (250)
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Microanalysis of glycosaminoglycans
Analytical Biochemistry, 1981Abstract A sensitive and versatile method for the qualitative and quantitative determination of glycosaminoglycans (GAGs) is described. An enriched GAG fraction was subjected to nuclease enzyme treatment and to an appropriate sequence of GAG degrading enzymes—Streptomyces hyaluronidase, chondroitinase AC and ABC, and endo-β- d -galactosidase—and ...
M, Breen +5 more
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Glycosaminoglycans in Neurofibromas
The Journal of Dermatology, 1990AbstractGlycosaminoglycan (GAG) contents in neurofibromas (NFs) were examined to clarify how well they corresponded to their histological features. Eight cutaneous NFs and three plexiform NFs from five patients with Recklinghausen's (R) disease, two senile NFs, and control dermis were subjected to the isolation of GAGs.
T, Sasaki, S, Onodera
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Glycosaminoglycans in the Human Cornea: Age-Related Changes [PDF]
Aim To investigate possible age-related changes in glycosaminoglycans (GAGs) in the human cornea. The substances today called GAGs were previously referred to as mucopolysaccharides.
Elena Pacella +2 more
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Glycosaminoglycans as polyelectrolytes
Advances in Colloid and Interface Science, 2010One of the barriers to understanding structure-property relations for glycosaminoglycans has been the lack of constructive interplay between the principles and methodologies of the life sciences (molecular biology, biochemistry and cell biology) and the physical sciences, particularly in the field of polyelectrolytes.
Seyrek, E, Dubin, P
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Glycosaminoglycans in Urolithiasis
Nephron, 2008To determine if there are differences in urinary glycosaminoglycan (GAG) concentrations, 43 stone-forming patients and 37 healthy control subjects of both sexes were studied. Urinary concentrations of calcium, magnesium, creatinine, uric acid and GAGs were determined.
A, Nesse +4 more
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Glycosaminoglycans: Chemistry and Biology emphasizes several areas of glycosaminoglycan research especially analysis and application of GAGs using a variety of approaches.
Balagurunathan, Kuberan.editor.edthttp://id.loc.gov/vocabulary/relators/edt +3 more
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Brain glycosaminoglycans and glycosaminoglycan sulphotransferase in sanfilippo syndrome
Clinica Chimica Acta, 1970Analysis of various glycosaminoglycans in brain obtained from two patients with Sanfilippo syndrome indicates that the major glycosaminoglycan accumulated in brain was heparan sulphate. Dermatan sulphate was also increased in one case as compared to normal, whereas only heparan sulphate was present in the other. Chondroitin-4-sulphate sulphotransferase
E, George, B K, Bachhawat
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Glycosaminoglycans and Neuroprotection
2011Glycosaminoglycans (GAGs) are basic building blocks of the ground substance of the extracellular matrix and present at the cellular level as an important component of the glycocalyx covering the cell membrane. In addition to the general role of GAGs in maintaining the integrity of the cell and extracellular matrix by retaining water, certain GAGs ...
B, Dudas, K, Semeniken
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Glycosaminoglycan microarrays for studying glycosaminoglycan–protein systems
Carbohydrate PolymersMore than 3000 proteins are now known to bind to glycosaminoglycans (GAGs). Yet, GAG-protein systems are rather poorly understood in terms of selectivity of recognition, molecular mechanism of action, and translational promise. High-throughput screening (HTS) technologies are critically needed for studying GAG biology and developing GAG-based ...
John E, Chittum +2 more
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Therapeutic Applications of Glycosaminoglycans
Current Medicinal Chemistry, 2006Complex polysaccharides, hyaluronic acid or hyaluronan (HA), keratan sulfate (KS), chondroitin sulfates (CSs) and heparin (Hep)/heparan sulfate (HS), are a class of ubiquitous molecules exhibiting a wide range of biological functions. They are widely distributed as glycosaminoglycans (GAGs) sidechains of proteoglycans (PGs) in the extracellular matrix ...
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