Results 201 to 210 of about 64,705 (285)

Morquio syndrome masquerading as juvenile idiopathic Arthritis: A case report. [PDF]

open access: yesRadiol Case Rep
Kadiri ZA   +6 more
europepmc   +1 more source

Sclerostin regulates bone morphogenetic protein (BMP) bioavailability through interactions with BMP complexes and fibrillin microfibrils

open access: yesThe FEBS Journal, EarlyView.
Sclerostin (SOST) is a multifunctional extracellular modulator of BMP and Wnt signaling. SOST binds with high affinity to fibrillin‐1 and fibrillin‐2, localizing it to fibrillin microfibrils and regulating its extracellular bioavailability. Fibrillin‐bound SOST cannot engage BMP‐7 prodomain (PD) complexes, revealing a competitive mechanism that ...
Annkatrin Correns   +11 more
wiley   +1 more source

Surface charge alterations in urinary extracellular vesicles mirror diabetic kidney disease pathophysiology

open access: yesThe FEBS Journal, EarlyView.
This study reveals that changes in the electrical charge, that is zeta potential of large extracellular vesicles (uEVs) found in urine, can reflect disease progression from diabetes to kidney scarring (fibrosis). With further clinical development, measurement of uEVs charge could provide a simple, noninvasive way to monitor disease progression and help
Melanie Tepuš   +6 more
wiley   +1 more source

The Valorization Potential of Freshwater Fish, Including Common Carp (<i>Cyprinus carpio</i>), in the Context of Obtaining Functional Food Ingredients. [PDF]

open access: yesFoods
Tokarczyk G   +7 more
europepmc   +1 more source

Hyaluronic Acid Modulates IL1β‐Induced Cytokine Profile of Gingival Mesenchymal Stem Cells

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aim Hyaluronic acid (HA) possesses anti‐inflammatory properties critical for periodontal wound healing. In this study, we aimed to evaluate the role of cross‐linked high‐molecular‐weight (HMW) HA on cytokine mRNA expression, cell viability and migration in IL‐1β‐stimulated gingival mesenchymal stem cells (gMSCs).
Sema S. Hakki   +3 more
wiley   +1 more source

The MacBrain Resource Center (MBRC) rhesus macaque embryonic brain histology datasets

open access: yesJournal of Anatomy, EarlyView.
We introduce the MacBrain Resource Center (MBRC) Collections of rhesus macaque embryonic brain tissue. Here, we illustrate histo‐ and immunohistology from our dynamically growing Collection 6, which currently contains >10,000 zoomable and downloadable images from n = 14 male and female embryos from early to late in gestation.
Valeria Mendoza‐Silva   +11 more
wiley   +1 more source

Development of a pro‐angiogenic stem cell‐derived vascular cell extracellular matrix‐decorated hyaluronic acid hydrogel

open access: yesJournal of Anatomy, EarlyView.
This work focuses on the development of a hyaluronic acid‐based hydrogel decorated with pro‐angiogenic hiPSC‐derived vascular cell decellularised ECM, for the treatment of diabetic foot ulcers. Taken together, the results presented here show the potential of our hydrogel to enhance both angiogenesis and re‐vascularisation of wounds.
Louise Hosty   +9 more
wiley   +1 more source

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