Results 31 to 40 of about 85,805 (344)

Glycosaminoglycan distribution in the rat uterine cervix during the estrous cycle

Clinics, 2010
OBJECTIVE: To analyze the amount of glycosaminoglycans in the uterine cervix during each phase of the rat estrous cycle. DESIGN: Based on vaginal smears, forty female, regularly cycling rats were divided into four groups (n = 10 for each group): GI ...
Jairo Jose Matozinho Cubas, Ricardo Santos Simões, Ricardo Martins Oliveira-Filho, Manuel Jesus Simões, Edmund C Baracat, José Maria Soares-Jr   +5 more
doaj   +1 more source

Glycosaminoglycan–Protein Interactions: The First Draft of the Glycosaminoglycan Interactome [PDF]

Journal of Histochemistry & Cytochemistry, 2020
The six mammalian glycosaminoglycans (GAGs), chondroitin sulfate, dermatan sulfate, heparin, heparan sulfate, hyaluronan, and keratan sulfate, are linear polysaccharides. Except for hyaluronan, they are sulfated to various extent, and covalently attached to proteins to form proteoglycans.
Sylvain D. Vallet, Olivier Clerc, Sylvie Ricard-Blum   +2 more
openaire   +3 more sources

The effect of the level of total sodium deposited in the myocardium on its stiffness [PDF]

Терапевтический архив, 2017
Aim. To determine a relationship between the level of total sodium in the myocardium to its stiffness. Subjects and methods. The investigation enrolled 18 hypertensive patients who had suddenly died; their mean age was 40±10 years; mean waist ...
G P Arutyunov, D O Dragunov, G P Arutyunov, A V Sokolova, I P Papyshev, E M Kildyushov, V V Negrebetsky, V N Fedorova   +7 more
doaj   +1 more source

Bioinformatics of glycosaminoglycans

Perspectives in Science, 2017
SummaryCell surface heparan sulfates modulate many signalling pathways by binding growth factors and growth factor receptors. Expressed in a spatially and temporally regulated manner, these highly sulfated polysaccharides play important roles in all aspects of animal physiology.
Han Hu, Joseph Zaia, Yang Mao, Yu Huang, Cheng Lin   +4 more
openaire   +2 more sources

Proton Conductivity of Glycosaminoglycans [PDF]

PLOS ONE, 2018
AbstractProton (H+) conductivity is important in many natural phenomena including oxidative phosphorylation in mitochondria and archea, uncoupling membrane potentials by the antibiotic Gramicidin, and proton actuated bioluminescence in dinoflagellate.
Selberg, John, Jia, Manping, Rolandi, Marco   +2 more
openaire   +4 more sources

Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells

Nature Microbiology, 2019
Clostridium difficile toxin A (TcdA) is a major exotoxin contributing to disruption of the colonic epithelium during C. difficile infection. TcdA contains a carbohydrate-binding combined repetitive oligopeptides (CROPs) domain that mediates its ...
Liang Tao, Songhai Tian, Jie Zhang, Zhuoming Liu, Lindsey R. Robinson-McCarthy, Shin-Ichiro Miyashita, D. Breault, R. Gerhard, S. Oottamasathien, S. Whelan, M. Dong   +10 more
semanticscholar   +1 more source

Development of a newborn screening tool for mucopolysaccharidosis type I based on bivariate normal limits: Using glycosaminoglycan and alpha‐L‐iduronidase determinations on dried blood spots to predict symptoms

JIMD Reports, 2020
Purpose Current newborn screening (NBS) for mucopolysaccharidosis type I (MPSI) has very high false positive rates and low positive predictive values (PPVs).
Thomas J. Langan, Kabir Jalal, Amy L. Barczykowski, Randy L. Carter, Molly Stapleton, Kenji Orii, Toshiyuki Fukao, Hironori Kobayashi, Seiji Yamaguchi, Shunji Tomatsu   +9 more
doaj   +1 more source

Mechanistic insights into molecular evolution of species-specific differential glycosaminoglycan binding surfaces in growth-related oncogene chemokines [PDF]

Royal Society Open Science, 2017
Chemokines are chemotactic cytokines involved in leucocyte trafficking to infected tissue. Growth-related oncogene (GRO) chemokines namely CXCL1, CXCL2 and CXCL3 are neutrophil activating chemokines sharing a conserved three-dimensional structure, but ...
Khushboo Gulati, Minal Jamsandekar, Krishna Mohan Poluri   +2 more
doaj   +1 more source

Age-related functional changes of total thyroid hormones and glycosaminoglycans in growing calves [PDF]

Veterinary World, 2020
Background and Aim: During the physiological growing, thyroid and proteoglycan glycosaminoglycan (GAG) changes dynamically occur, according to genetic and non-genetic factors.
Pietro Medica, Cristina Cravana, Alida Maria Ferlazzo, Esterina Fazio   +3 more
doaj   +1 more source

Glycosaminoglycan Functionalized Nanoparticles Exploit Glycosaminoglycan Functions [PDF]

, 2014
Nanoparticles are being explored for a variety of applications including medical imaging, drug delivery, and biochemical detection. Surface functionalization of nanoparticles with glycosaminoglycans (GAGs) is an attractive strategy that is only starting to be investigated to improve their properties for biological and therapeutic applications.
Vassie, JA, Whitelock, JM, Lord, MS
openaire   +3 more sources