Results 31 to 40 of about 52,449 (293)

Glycosaminoglycans: From Vascular Physiology to Tissue Engineering Applications

open access: yesFrontiers in Chemistry, 2021
Cardiovascular diseases represent the number one cause of death globally, with atherosclerosis a major contributor. Despite the clinical need for functional arterial substitutes, success has been limited to arterial replacements of large-caliber vessels (
Antonio Junior Lepedda   +5 more
doaj   +1 more source

Glycosaminoglycan Functionalized Nanoparticles Exploit Glycosaminoglycan Functions [PDF]

open access: yes, 2014
Nanoparticles are being explored for a variety of applications including medical imaging, drug delivery, and biochemical detection. Surface functionalization of nanoparticles with glycosaminoglycans (GAGs) is an attractive strategy that is only starting to be investigated to improve their properties for biological and therapeutic applications.
Vassie, JA, Whitelock, JM, Lord, MS
openaire   +3 more sources

Possibility of laboratory assessment of the state of connective tissue

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2015
This article deals with the possibilities of laboratory assessment of the state of the connective tissue. It contains brief information about its structure, functions and roles of the various components in the development of pathological processes, and ...
G. A. Berezovskaya, V. L. Emanuel
doaj   +1 more source

Urinary glycosaminoglycans excretion and the effect of dimethyl sulfoxide in an experimental model of non-bacterial cystitis

open access: yesInternational Brazilian Journal of Urology, 2008
PURPOSE: We reproduced a non-bacterial experimental model to assess bladder inflammation and urinary glycosaminoglycans (GAG) excretion and examined the effect of dimethyl sulfoxide (DMSO).
Roberto Soler   +9 more
doaj   +1 more source

The glycosaminoglycans of human plasma [PDF]

open access: yesJournal of Clinical Investigation, 1969
A method is proposed for the measurement of glycosaminoglycans (GAG) on 5-10 ml of plasma. It is based on the adsorption of GAG on small ECTEOLA columns followed by measurement of the hexuronic acid in the NaCl eluates. Routine use of the method has indicated the presence of a GAG fraction that adsorbs readily on ECTEOLA ("free" GAG) and of another ...
CALATRONI, Alberto   +2 more
openaire   +4 more sources

The effect of the level of total sodium deposited in the myocardium on its stiffness [PDF]

open access: yesТерапевтический архив, 2017
Aim. To determine a relationship between the level of total sodium in the myocardium to its stiffness. Subjects and methods. The investigation enrolled 18 hypertensive patients who had suddenly died; their mean age was 40±10 years; mean waist ...
G P Arutyunov   +7 more
doaj   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Mucopolysaccharidosis

open access: yesTaiwan Journal of Ophthalmology, 2023
Mucopolysaccharidosis are group of inherited metabolic diseases caused by the absence or malfunctioning of lysosomal enzymes resulting in accumulation of glycosaminoglycans. Over time this accumulation damages cells, tissues, and organs.
Kusumitha Bhakthaganesh   +5 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Sulfated glycosaminoglycans in human vocal fold lamina propria

open access: yesBrazilian Journal of Otorhinolaryngology
Introduction: The distribution, concentration and function of glycosaminoglycans in the various vocal fold tissues are still unclear. Objective: To evaluate the distribution and concentration of sulfated glycosaminoglycans in different layers of the ...
Sung Woo Park   +4 more
doaj   +1 more source

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