Results 41 to 50 of about 85,805 (344)

Glycosaminoglycans: From Vascular Physiology to Tissue Engineering Applications

open access: yesFrontiers in Chemistry, 2021
Cardiovascular diseases represent the number one cause of death globally, with atherosclerosis a major contributor. Despite the clinical need for functional arterial substitutes, success has been limited to arterial replacements of large-caliber vessels (
Antonio Junior Lepedda   +5 more
doaj   +1 more source

Influence of combined nitrate and fluoride intoxication on connective tissue disorders in rats gastric mucosa [PDF]

open access: yesArchives of the Balkan Medical Union, 2019
Introduction. Certain regions in Europe and Ukraine have high concentration of fluorides in drinking waters. Highly developed agriculture can result in increased concentration of nitrates in ground and drinking waters. Therefore, their combined excessive
Oleh Y. AKIMOV   +2 more
doaj   +1 more source

Interaction of Zika Virus Envelope Protein with Glycosaminoglycans.

open access: yesBiochemistry, 2017
In February 2016, the World Health Organization declared a Public Health Emergency of International Concern on Zika Virus (ZIKV), because of its association with severe fetal anomalies of congenitally infected humans.
S. Kim   +8 more
semanticscholar   +1 more source

Chemokine‐Capturing Wound Contact Layer Rescues Dermal Healing

open access: yesAdvanced Science, 2021
Excessive inflammation often impedes the healing of chronic wounds. Scavenging of chemokines by multiarmed poly(ethylene glycol)‐glycosaminoglycan (starPEG‐GAG) hydrogels has recently been shown to support regeneration in a diabetic mouse chronic skin ...
Lucas Schirmer   +3 more
doaj   +1 more source

The glycosaminoglycans of human plasma [PDF]

open access: yesJournal of Clinical Investigation, 1969
A method is proposed for the measurement of glycosaminoglycans (GAG) on 5-10 ml of plasma. It is based on the adsorption of GAG on small ECTEOLA columns followed by measurement of the hexuronic acid in the NaCl eluates. Routine use of the method has indicated the presence of a GAG fraction that adsorbs readily on ECTEOLA ("free" GAG) and of another ...
CALATRONI, Alberto   +2 more
openaire   +4 more sources

Mucopolysaccharidosis Type 1 among Children—Neuroradiological Perspective Based on Single Centre Experience and Literature Review

open access: yesMetabolites, 2023
Mucopolysaccharidosis 1 (MPS 1) is a group of rare lysosomal genetic disorders resulting from the accumulation of undegraded glycosaminoglycans (GAGs) leading to multiorgan damage. Neurological symptoms vary from mild to severe.
Magdalena Machnikowska-Sokołowska   +5 more
doaj   +1 more source

Mechanism of endometrial MUC2 in reproductive performance in mice through PI3K/AKT signaling pathway after lipopolysaccharide treatment

open access: yesEcotoxicology and Environmental Safety, 2022
The objective of this study was to investigate the effects of exposure to endotoxin on the reproductive performance of humans and animals in pregnancy and delivery period.
Ming-ming Zhang   +7 more
doaj  

Regional Variation in Androgen Receptor Expression and Biomechanical Properties May Contribute to Cryptorchidism Susceptibility in the LE/orl Rat

open access: yesFrontiers in Endocrinology, 2018
Background: The process of testicular descent requires androgen and insulin-like 3, hormones secreted by fetal Leydig cells. Knowledge concerning distinct and common functions of these hormones in regulating development of the fetal gubernaculum remains ...
Joshua T. Morgan   +7 more
doaj   +1 more source

Glycans as Modulators for the Formation and Functional Properties of Neutrophil Extracellular Traps: Used by the Forces of Good and Evil

open access: yesFrontiers in Immunology, 2019
A very common mechanism to trap pathogens is the release of DNA. Like flies in a spider's web, pathogens are enclosed in a sticky chromatin meshwork. Interestingly, plants already use this mechanism to catch bacteria.
Kim F. Bornhöfft, Sebastian P. Galuska
doaj   +1 more source

Diagnosis of Mucopolysaccharidoses and Mucolipidosis by Assaying Multiplex Enzymes and Glycosaminoglycans

open access: yesDiagnostics, 2021
Mucopolysaccharidoses (MPS) and mucolipidosis (ML II/III) are a group of lysosomal storage disorders (LSDs) that occur due to a dysfunction of the lysosomal hydrolases responsible for the catabolism of glycosaminoglycans (GAGs).
Nivethitha Arunkumar   +14 more
doaj   +1 more source

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