Proteoglycans and their heterogeneous glycosaminoglycans at the atomic scale.
Proteoglycan spatiotemporal organization underpins extracellular matrix biology, but atomic scale glimpses of this microarchitecture are obscured by glycosaminoglycan size and complexity.
Benedict M. Sattelle+3 more
semanticscholar +1 more source
The binding of glycosaminoglycans to peptides : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]
The overall aim this study was to examine the possibility of using immobilised polypeptide chains to fractionate/separate Glycosaminoglycans (GAG's) from mixtures. Initially individual samples of three GAG classes (chondroitin sulphate, dermatan sulphate
Taylor, Grant John
core
The role of urate and xanthine oxidase in vascular oxidative stress:Future directions [PDF]
Vascular oxidative stress has been shown to be a potent factor in the pathophysiology of endothelial dysfunction. Despite current optimal evidence-based therapy, mortality from various cardiovascular disorders remains high.
George, Jacob, Struthers, Allan
core +4 more sources
FIBCD1 is an endocytic GAG receptor associated with a novel neurodevelopmental disorder
Whole‐exome sequencing of two patients with idiopathic complex neurodevelopmental disorder (NDD) identified biallelic variants of unknown significance within FIBCD1, encoding an endocytic acetyl group‐binding transmembrane receptor with no known function
Christopher W Fell+28 more
doaj +1 more source
Hepatitis C virus relies on lipoproteins for its life cycle [PDF]
Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma.
Alonzi, Tonino+5 more
core +1 more source
On Top of the Alveolar Epithelium: Surfactant and the Glycocalyx [PDF]
Gas exchange in the lung takes place via the air-blood barrier in the septal walls of alveoli. The tissue elements that oxygen molecules have to cross are the alveolar epithelium, the interstitium and the capillary endothelium.
Hegermann, Jan+8 more
core +1 more source
Distribution features of the rats’ major salivary glands cells glycoproteins during early postnatal period after antenatal antigen action [PDF]
Background. Nowadays, in the diseases’ structure, according to literature data, one of the leading place take pathological condition connecting with the salivary glands’ inflammatory and dystrophic disorders.
Syrtsov V.K., Maslova І.N.
doaj
PURPOSE: We reproduced a non-bacterial experimental model to assess bladder inflammation and urinary glycosaminoglycans (GAG) excretion and examined the effect of dimethyl sulfoxide (DMSO).
Roberto Soler+9 more
doaj +1 more source
Quantification of heparin in complex matrices (including urine) using a mix-and-read fluorescence assay [PDF]
Heparin is an important anticoagulant drug, about one billion doses are produced annually. It is a polydisperse sulfated polysaccharide, and the inherent heterogeneity makes the analysis of heparin difficult. The global crisis resulting from adulterated heparin in 2008 has drawn renewed attention to the challenges that are associated with the quality ...
arxiv
Initial interaction of citrate-coated iron oxide nanoparticles with the glycocalyx of THP-1 monocytes assessed by real-time magnetic particle spectroscopy and electron microscopy [PDF]
Interaction with biological material can alter physicochemical parameters of magnetic nanoparticles and might thereby change their magnetic behavior with potentially important implications for various nanoparticle applications.
Ludwig, Antje+7 more
core +1 more source