Results 91 to 100 of about 32,114 (276)

Structural insights into xyloglucan recognition by an ABC transporter from a Gram‐positive, thermophilic bacterium

open access: yesThe FEBS Journal, EarlyView.
Athe_2052 is an ABC transporter substrate‐binding protein that recognizes xyloglucan heptasaccharide (XXXG), a soluble breakdown product of plant xyloglucan. The crystal structure of Athe_2052, together with binding assays and computational modeling, shows how XXXG is recognized by this sugar transporter.
Hansen Tjo   +6 more
wiley   +1 more source

Surface charge alterations in urinary extracellular vesicles mirror diabetic kidney disease pathophysiology

open access: yesThe FEBS Journal, EarlyView.
This study reveals that changes in the electrical charge, that is zeta potential of large extracellular vesicles (uEVs) found in urine, can reflect disease progression from diabetes to kidney scarring (fibrosis). With further clinical development, measurement of uEVs charge could provide a simple, noninvasive way to monitor disease progression and help
Melanie Tepuš   +6 more
wiley   +1 more source

Benign by design: A paradigm shift in cosmetic ingredient development

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Benign by design strategies enable the creation of biodegradable cosmetic ingredients, reducing environmental persistence while maintaining the intended biological activity. This work compiles design rules and tools to guide the development of more sustainable molecules for the cosmetics industry.
Sandra Mota   +3 more
wiley   +1 more source

Studies into the Stereo Selective Synthesis of Glycosidase Inhibitors.

open access: yes, 2004
The goal of our research was to develop an enantiopure glycosidase inhibitor. Glycosidase inhibitors are similar in structure to sugar molecules, and therefore lock up enzymes used in the consumption of sugars for respiration.
Vachher-Gnanathurai, Amit
core  

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

open access: yesInsect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto   +2 more
wiley   +1 more source

Biotransformation of monoterpenols upon pre‐treatment with oregano essential oil vapour alleviates downy mildew susceptibility in grapevine leaves

open access: yesPlant Biology, EarlyView.
Pre‐treatment of grapevine plants with oregano essential oil vapour alleviates downy mildew susceptibility by accumulation of monoterpenol glycosides. Abstract Grapevine downy mildew, caused by the oomycete Plasmopara viticola, is a destructive disease that causes major economic losses as most elite grapevine cultivars are susceptible to this pathogen.
J. R. P. E. Mars   +6 more
wiley   +1 more source

Stimuli‐Responsive Lipid‐Based Nanocarriers for Antimicrobial Therapy

open access: yesAdvanced Therapeutics, Volume 9, Issue 11, November 2026.
This manuscript demonstrated, through a scoping review of the literature, that modifying lipid nanocarriers with organic and inorganic excipients is a promising alternative to increase in vitro drug release of antimicrobial compounds under the studied stimulus and significantly enhance in vitro and in vivo antimicrobial activity compared to isolated ...
Brenda Maria Silva Bezerra   +5 more
wiley   +1 more source

Altered glycosidase Activities at Physiological pH in the Pathogenesis of Sepsis

open access: yes, 2020
Aziz P, Haslund-Gourley B, Heithoff D, et al. Altered glycosidase Activities at Physiological pH in the Pathogenesis of Sepsis. In: FASEB JOURNAL. Vol 34.
Westman, Julia   +9 more
core   +1 more source

Tailored Covalent Organic Frameworks Enable the Encapsulation of Living Cells to Produce Rare Ginsenoside

open access: yesAdvanced Science, Volume 13, Issue 61, 3 November 2026.
This work reports the in situ fabrication of Escherichia coli@covalent organic frameworks (E. coli@COFs) in phosphate‐buffered saline. The COFs form an exoskeleton on E. coli, protecting intracellular β‐glucosidase (Ssbgl) while enhancing mass transfer.
Fengmei Liu   +6 more
wiley   +1 more source

Towards Tuneable Retaining Glycosidase-Inhibiting Peptides by Mimicry of a Plant Flavonol Warhead [PDF]

open access: yes, 2017
Retaining glycosidases are an important class of enzymes involved in glycan degradation. To study better the role of specific enzymes in deglycosylation processes, and thereby the importance of particular glycosylation patterns, a set of potent ...
Afd Chemical Biology and Drug Discovery   +7 more
core   +1 more source

Home - About - Disclaimer - Privacy