Results 71 to 80 of about 32,114 (276)

GLYCOSIDASES IN FOWL SEMEN [PDF]

Reproduction, 1974
It seems probable that the glycosidases in spermatozoa and seminal plasma are involved in the fertilization process. In mammals, this possibility may be supported by the presence of several glycosidases, hyaluronidase and neuraminidase (Hartree & Srivastava, 1965; Srivastava, Adams & Hartree, 1965; Srivastava, Zaneveld & Williams, 1970 ...
openaire   +2 more sources

Fluorinated Iminosugar Glycomimetics: Synthesis and Activity as GCase Ligands

European Journal of Organic Chemistry, EarlyView.
DAST‐mediated deoxyfluorination of suitably functionalized piperidines provided regio‐ and stereoselective access to fluorinated piperidine and pyrrolidine glycomimetics, the latter arising from an unusual ring‐contraction process. Fluorination generally enhanced β‐glucocerebrosidase (GCase) inhibitory potency, but lost PC activity toward L444P/L444P ...
Francesca Mangiavacchi, Alessio Morano, Cosimo Margheri, Cristina Faggi, Amelia Morrone, Camilla Matassini, Francesca Clemente, Andrea Goti, Martina Cacciarini, Francesca Cardona   +9 more
wiley   +1 more source

Glycosphingolipids and Infection. Potential New Therapeutic Avenues

Frontiers in Cell and Developmental Biology, 2019
Glycosphingolipids (GSLs), the main topic of this review, are a subclass of sphingolipids. With their glycans exposed to the extracellular space, glycosphingolipids are ubiquitous components of the plasma membrane of cells.
Johannes M. F. G. Aerts, M. Artola, M. van Eijk, M. J. Ferraz, R. G. Boot   +4 more
doaj   +1 more source

Sugar hydrazide imides: a new family of glycosidase inhibitors

, 2017
We present a new type of glycosidase inhibitor including a unique hydrazide imide moiety, which displays inhibition in the low micromolar range.
José G. Fernández-Bolaños, Óscar Lopéz, Emil Lindbäck, Magne O. Sydnes, Ådne Tobiesen   +4 more
core   +1 more source

Antidiabetic and antiparasitic potentials: Inhibition effects of some natural antioxidant compounds on alpha-glycosidase, alpha-amylase and human glutathione S-transferase enzymes [PDF]

, 2018
WOS: 000447682100084PubMed: 30076927The glutathione S-transferase (GST) was purified from fresh blood erythrocytes using affinity column chromatography.
Bastem, E., Şen, F., Taslimi, Parham, Gulcin, Ilhami, Kufrevioglu, Omer Irfan, Turkan, Fikret, Kufrevioglu, Omer Han, Sen, Fatih, Sadeghian, N., Kufrevioglu, O.I., Gulçin, İ., Taslimi, P., Aygun, Aywnur, Bastem, Enes, Aygün, Ayşenur, Aygün, A., Sadeghian, Nastaran   +16 more
core   +1 more source

Correlations Among Glycemia and Glucose Variability, Thyroid Hormones, and Albuminuria in Patients With Type 2 Diabetes Mellitus

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hyperglycemia, glucose fluctuations, and thyroid dysfunction contribute to the progression of diabetic nephropathy. This study aimed to investigate the associations of glycemia, glucose variability, and thyroid hormones with albuminuria in patients with type 2 diabetes mellitus (T2DM). In total, 451 T2DM patients were included.
Na Luo, Shang‐Yong Feng, Hui Chen, Dun‐Min She, Yan Liu, Ying Li, Cai‐Feng Yan, Zhen‐Wen Zhang, Jing Chen, Xiao‐Li Cai, Gao‐Yu Zhao, Hui Yu, Yan Wang   +12 more
wiley   +1 more source

Sialic acid: a sweet swing between mammalian host and Trypanosoma cruzi

Frontiers in Immunology, 2012
Commonly found at the outermost ends of complex carbohydrates in extracellular medium or on outer cell membranes, sialic acids play important roles in a myriad of biological processes.
Leonardo eFreire-de-Lima, Isadora A. Oliveira, Jorge L. Neves, Luciana L. Penha, Frederico eAlisson-Silva, Wagner B. Dias, Adriane Regina Todeschini   +6 more
doaj   +1 more source

Post-print de Current Chemical Biosynthetic Pathways to Glycosidase Inhibitors

, 2020
Glycosidase inhibitors are important compounds that can interfere with ...
Tomás Tejero, Ignacio Delso, Fernando Gomollón-Bel, Pedro Merino   +3 more
core  

Pseudouridine Monophosphate Glycosidase: A New Glycosidase Mechanism

, 2016
Pseudouridine (Ψ), the most abundant modification in RNA, is synthesized in situ using Ψ synthase. Recently, a pathway for the degradation of Ψ was described [Preumont, A., Snoussi, K., Stroobant, V., Collet, J. F., and Van Schaftingen, E. (2008) J. Biol.
Tadhg P. Begley (170128), Nilkamal Mahanta (1898020), Siyu Huang (2024458), Steven E. Ealick (43371)   +3 more
core   +1 more source

Excursions of blood glycosidase activities in the pathogenesis and prognosis of Sepsis

, 2021
Aziz PV, Lewis BJ, Haslund-Gourley BS, et al. Excursions of blood glycosidase activities in the pathogenesis and prognosis of Sepsis. Glycobiology .
Ilse, Mai-Britt, Heithoff, Douglas M., Fried, Jeffrey C., Westman, Julia S., Lübke, Torben ; https://orcid.org/, Restagno, Damien, Marth, Jamey D., Aziz, Peter V., Lewis, Benjamin J., Haslund-Gourley, Benjamin S., Biskup, S., Das, A., Hennig, R., Puk, O., Lesinski-Schiedat, A., Beimdiek, J., Rapp, E., Buettner, F., Burock, R.   +18 more
core   +1 more source